Microbial Genetics
MicroRNA-29a promotes apoptosis of monocytes by targeting STAT3 during sepsis
Authors: X. Song, C.T. Wang and X.H. Geng
Sepsis is a major cause of morbidity and mortality in critically ill patients. The sepsis syndrome results from a dysregulated inflammatory response to infection that leads to multiple-organ failure, but the underlying mechanisms remain poorly understood. More and more reports show that microRNAs (miRNAs) play an important role in sepsis. In the progressi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.37
- DOI:
- 10.4238/2015.October.28.37
Genetic diversity of Setipinna taty (Engraulidae) populations from the China Sea based on mitochondrial DNA control region sequences
Authors: H.Y. Li, T.J. Xu, Y.Z. Cheng, D.Q. Sun and R.X. Wang
The genetic diversity of Setipinna taty, which is commercially fished in the China Sea, was studied based on mitochondrial DNA control region sequences. PCR was used to amplify the control region fragment in 100 individuals of S. taty collected from Weihai (WH), Yantai (YT), Zhoushan (ZS), Xiangshan (XS), and Ninghai (NH) in C.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.9.1
- DOI:
- 10.4238/2012.May.9.1
TGF-�²1 and Serpine 1 expression changes in traumatic deep vein thrombosis
Authors: J.W. Mo, D.F. Zhang, G.L. Ji, X.Z. Liu and B. Fan
The objective of this study was to investigate the expression changes of transforming growth factor β1 (TGF-β1) and Serpine 1 in rats with traumatic deep vein thrombosis (DVT). In total, 60 male Sprague Dawley rats were divided into model (N = 50) and control groups (Group A, N = 10). From the model group, 10 rats were randomly selected after mo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.3
- DOI:
- 10.4238/2015.October.29.3
Expression of macrophage migration-inhibitory factor in duodenal ulcer and its relation to Helicobacter pylori infection
Authors: X.H. Yu, Q. Zhang, X.P. Yang, W. Yang, F. Dai, Z. Qian, Z.L. Wang, C.F. Wu, H.Z. Zhao and G.H. Wang
The aim of this study was to examine the expression of macrophage migration-inhibitory factor (MIF) in duodenal ulcer epithelial cells and its relation to Helicobacter pylori (Hp) infection, and to discuss the pathogenic roles of MIF expression and Hp infection in duodenal ulcer. MIF protein and mRNA expression was examined in samples from patients with d.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.6
- DOI:
- 10.4238/2015.October.29.6
Cloning and expression of class I chitinases in Hami melon after Penicillium infection
Authors: F.Y. Jiang, B.B. Shui, F.X. Tang and C.H. Shan
Chitinases are important disease-related proteins that play critical roles in plant defense against disease. To investigate the function of chitinases in the resistance of Hami melon to Penicillium infection, the gene encoding chitinases, HmCHT-2, was cloned and RT-PCR was used to measure expression levels of HmCHT-2. When the.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019085
- DOI:
- 10.4238/gmr16019085
Africanized honey bees more efficiently convert protein diets into hemolymph protein than do Carniolan bees (Apis mellifera carnica)
Authors: F.A. Cappelari, A.P. Turcatto, M.M. Morais and D. De Jong
The superiority of Africanized over European honey bees in tropical and subtropical regions of the New World is both well documented and poorly understood. As part of an effort to try to understand the process by which the displacement of European bees occurred, we examined the ability of these two types of bees and of hybrids.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr628
- DOI:
- 10.4238/vol8-4gmr628
Characterization of microsatellite markers in cassava based on microsatellite-AFLP technique
Authors: S. Whankaew, S. Sraphet, R. Thaikert, D.R. Smith and K. Triwitayakorn
We developed molecular markers for cassava based on the microsatellite-amplified fragment length polymorphism (M-AFLP) technique. Twenty primer pairs were developed and used for the analysis of 48 samples of Manihot species, consisting of M. esculenta (33), M. esculenta ssp flabellifolia (3), M. chlorosticta (3), M. carthagine.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.15.2
- DOI:
- 10.4238/2012.May.15.2
Genetic diversity analysis of isolates of the fungal bean pathogen Pseudocercospora griseola from central and southern Brazil
Authors: A.K.R. Abadio, S.S. Lima, M.F. Santana, T.M.F. Salom�£o, A. Sartorato, E.S.G. Mizubuti, E.F. Ara�ºjo and M.V. de Queiroz
Planting resistant varieties is the most effective control measure against the angular leaf spot of dry beans, a fungal disease caused by Pseudocercospora griseola. However, dry bean varieties with durable resistance are not easily obtained. Knowledge about the genetic variability of the pathogen population is key for the succ.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.14.1
- DOI:
- 10.4238/2012.May.14.1
Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5
Authors: L. Van Nieuwenhove, S. Rog�©, V. Lejon, Y. Guisez and P. B�¼scher
At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement of the native VSGs by recombinant proteins or synthetic peptides, the seq.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.9.5
- DOI:
- 10.4238/2012.May.9.5
Establishment and initial characterization of SOX2-overexpressing NT2/D1 cell clones
Authors: D. Drakulic, A. Krstic and M. Stevanovic
SOX2, a universal marker of pluripotent stem cells, is a transcription factor that helps control embryonic development in vertebrates; its expression persists in neural stem/progenitor cells into adulthood. Considering the critical role of the SOX2 transcription factor in the regulation of genes required for self-renewal and p.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.15.9
- DOI:
- 10.4238/2012.May.15.9