Microbial Genetics
Expression of Pink1 with �±-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan
Authors: A.M. Todd and B.E. Staveley
Overexpression of the gene coding for α-synuclein has been shown to be an inherited cause of Parkinson disease. Our laboratory has previously co-expressed the parkin and Pink1 genes to rescue α-synuclein-induced phenotypes within a Drosophila model. To further investigate the effect of Pink1 in this model, we perfo.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.21.6
- DOI:
- 10.4238/2012.May.21.6
SYBR safeTM efficiently replaces ethidium bromide in Aspergillus fumigatus gene disruption
Authors: H.M.S. Canela, L.A. Takami and M.E.S. Ferreira
Invasive aspergillosis is a disease responsible for high mortality rates, caused mainly by Aspergillus fumigatus. The available drugs are limited and this disease continues to occur at an unacceptable frequency. Gene disruption is essential in the search for new drug targets. An efficient protocol for A. fumigatus gene disrupt.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019583
- DOI:
- 10.4238/gmr16019583
Microbiological quality and bacterial diversity of the tropical oyster Crassostrea rhizophorae in a monitored farming system and from natural stocks
Authors: M.T. Silva Neta, B.M. Maciel, A.T.S. Lopes, E.L.S. Marques,R.P. Rezende, G. Boehs
Microbiological evaluation is one of the most important parameters for analyzing the viability of an oyster farming system, which addresses public health and ecological concerns. Here, the microbiological quality of the oyster Crassostrea rhizophorae cultivated in a monitored environment and from natural beds in Bahia, northea.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.27
- DOI:
- 10.4238/2015.December.1.27
Multivariate approach in popcorn genotypes using the Ward-MLM strategy: morpho-agronomic analysis and incidence of Fusarium spp
Authors: R.N.F. Kurosawa, A.T. do Amaral Junior, F.H.L. Silva, A. dos Santos,M. Vivas, S.H. Kamphorst and G.F. Pena
The multivariate analyses are useful tools to estimate the genetic variability between accessions. In the breeding programs, the Ward-Modified Location Model (MLM) multivariate method has been a powerful strategy to quantify variability using quantitative and qualitative variables simultaneously. The present study was proposed.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019528
- DOI:
- 10.4238/gmr16019528
Genetic diversity and mating system of Copaifera langsdorffii (Leguminosae/Caesalpinioideae)
Authors: A. Gonela A.M. Sebbenn H.H. Soriani M.A. Mestriner C.A. Martinez A.L. Alzate-Marin
Copaifera langsdorffii, locally known as copaÃ?Âba, is a valuable tropical tree with medicinal properties of its oil. We studied the genetic variation, genetic structure, and the mating system of trees in stands of C. langsdorffii (Leguminosae/Caesalpinioideae) located in an extensive area between the Pardo and Mogi-GuaÃ?§u basins in SÃ?£o Paulo State, Br.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.27.6
- DOI:
- 10.4238/2013.February.27.6
Synonymous codon usage patterns in different parasitic platyhelminth mitochondrial genomes
Authors: L. Chen D.Y. Yang T.F. Liu X. Nong X. Huang Y. Xie Y. Fu W.P. Zheng R.H. Zhang X.H. Wu X.B. Gu S.X. Wang X.R. Peng G.Y. Yang
We analyzed synonymous codon usage patterns of the mitochondrial genomes of 43 parasitic platyhelminth species. The relative synonymous codon usage, the effective number of codons (NC) and the frequency of G+C at the third synonymously variable coding position were calculated. Correspondence analysis was used to determine the major variation trends shapin.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.27.8
- DOI:
- 10.4238/2013.February.27.8
Isolation and characterization of novel microsatellite markers for molecular genetic diversity in Siganus fuscescens
Authors: Y.F. Ning, Z.B. Li, Q.H. Li, G. Dai, J.B. Shangguan, Y. Yuan and Y.S. Huang
The rabbitfish Siganus fuscescens is an economically valuable species that is widely distributed throughout the estuaries, intertidal, and offshore coasts of the Indo-Pacific and eastern Mediterranean. Ten novel microsatellite loci from the genome of S. fuscescens were developed using the fast isolation protocol with amplified fragment length polymorphism.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.11
- DOI:
- 10.4238/2015.January.15.11
Characterization of chicken natural resistance-associated macrophage protein encoding genes (Nramp1 and Nramp2) and association with salmonellosis resistance
Authors: X.M. He M.X. Fang Z.T. Zhang Y.S. Hu X.Z. Jia D.L. He S.D. Liang Q.H. Nie X.Q. Zhang
Natural resistance-associated macrophage protein 1 and 2 encoding genes (Nramp1 and Nramp2) are related to many diseases. We cloned the cDNA of chicken Nramp1 and Nramp2 genes, characterized their expression and polymorphisms, and investigated the association of some SNPs with resistance to salmonellosis. The Nramp1 cDNA was 1746 bp long and the Nramp2 cD.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.30.5
- DOI:
- 10.4238/2013.January.30.5
Molecular analysis and frequency of Staphylococcus aureus virulence genes isolated from bloodstream infections in a teaching hospital in Tianjin, China
Authors: L.X. Wang Z.D. Hu Y.M. Hu B. Tian Jing Li F.X. Wang H. Yang H.R. Xu Y.C. Li J. Li
Staphylococcus aureus is an important cause of bloodstream infections worldwide. We examined the prevalence of genes that encode erythromycin ribosome methylase and bacterial toxins in S. aureus collected from bloodstream infections. Sixty different S. aureus isolates were obtained from blood cultures of patients who were admitted to a Teaching Hospital i.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.11.12
- DOI:
- 10.4238/2013.March.11.12
Genetic diversity of Burkholderia (Proteobacteria) species from the Caatinga and Atlantic rainforest biomes in Bahia, Brazil
Authors: A.C. Santini H.R.M. Santos E. Gross R.X. Corr�ªa
The genus Burkholderia (Ã?²-Proteobacteria) currently comprises more than 60 species, including parasites, symbionts and free-living organisms. Several new species of Burkholderia have recently been described showing a great diversity of phenotypes. We examined the diversity of Burkholderia spp in environmental samples collected from Caatinga and Atlantic r.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.11.13
- DOI:
- 10.4238/2013.March.11.13