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Medical Genetics

Medical Genetics   Research Article

Correlation between natriuretic peptide receptor C (NPR3) gene polymorphisms and hypertension in the Dai people of China

Authors: H. Sun, Z.Q. Yang, S.Y. Liu, L. Yu, K. Huang, K.Q. Lin, J.Y. Chu and X.Q. Huang

Hypertension affects one-fifth of the world population. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that correlated with hypertension in large samples. However, the genetic mutations leading to hypertension might differ among various populations, as they have different origins and are subjected to .. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.2
DOI:
10.4238/2015.August.3.2
Medical Genetics   Research Article

Feasibility of comfortable and secure intubation achieved with the Disposcope endoscope or Macintosh laryngoscope for patients in whom glottis viewing is difficult

Authors: X.-H. Li,Z. Sun and L.-L. He

We aimed to study the feasibility of a comfortable and secure intubation achieved with the Disposcope endoscope or Macintosh laryngoscope when glottis viewing is difficult. Forty adults scheduled for elective surgery under general anesthesia, in whom glottis viewing was difficult with the Macintosh laryngoscope (classified as Cormack-Lehane Grade III or I.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.19
DOI:
http://dx.doi.org/10.4238/2015.April.17.19
Medical Genetics   Research Article

Effect of HIF-1a/VEGF signaling pathway on plasma progesterone and ovarian prostaglandin F2a secretion during luteal development of pseudopregnant rats

Authors: X.Y. Pan, Z.H. Zhang, L.X. Wu and Z.C. Wang

The corpus luteum is a temporary endocrine structure in mammals that plays an important role in the female reproductive cycle and is formed from a ruptured and ovulated follicle with rapid angiogenesis. Vascular endothelial growth factor (VEGF) is thought to be vital in normal and abnormal angiogenesis in the ovary, but the molecular regulation of luteal .. Read More»

Genet. Mol. Res. 14(3):
2015.August.3.3
DOI:
10.4238/2015.August.3.3
Medical Genetics   Research Article

Investigating the prevention of hospital-acquired infection through standardized teaching ward rounds in clinical nursing

Authors: R. Zhang

This study aimed to explore the effect of standardized teaching ward rounds in clinical nursing on preventing hospital-acquired infection. The experimental group comprised 120 nursing students from our hospital selected between June 2010 and June 2012. The control group consisted of 120 nursing students selected from May 2008 to May 2010. Traditional teac.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.3
DOI:
http://dx.doi.org/10.4238/2015.April.22.3
Medical Genetics   Research Article

Transthoracic closure of atrial septal defect and ventricular septal defect without cardiopulmonary bypass

Authors: L. Wan,B.-T. Yu,Q.-C. Wu,L. Zeng,Q. Wang,J. Tang,Q.-R. Xu,H. Xu,W.-J. Wang,Y.-P. Cao and J.-C. Liu

The minimally invasive surgical transthoracic occlusion of an atrial septal defect (ASD) or a ventricular septal defect (VSD) is an increasingly widespread alternative treatment for congenital heart disease. The aim of this study is to summarize our clinical experience with minimally invasive surgical transthoracic occlusion of ASD and VSD without cardiop.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.4
DOI:
http://dx.doi.org/10.4238/2015.April.22.4
Medical Genetics   Research Article

T174M polymorphism in the angiotensinogen gene and risk of myocardial infarction: ameta-analysis

Authors: P.Y. Hu,Y.W. Wang,X.H. Pang and H.W. Wang

Numerous studies have evaluated the association between the T174M polymorphism in the angiotensinogen (AGT) gene and myocardial infarction (MI) risk. However, the specific association remains controversial because of small sample sizes and varied study designs among different studies. We performed a meta-analysis to assess this correlation. A comprehensiv.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.5
DOI:
http://dx.doi.org/10.4238/2015.April.22.5
Medical Genetics   Research Article

Clinical value of ultrasound-guided percutaneous biopsy of pulmonary lesions

Authors: R.J. Yang,Y.L. Yang,L.T. Ruan,L.J. Yuan,L.J. Chao,S. Chen and Y.Y. Duan

The purpose of this study was to evaluate the applicability of ultrasound-guided percutaneous biopsy for the diagnosis and differentiation of various pulmonary lesions in a Chinese population. A total of 338 pulmonary lesions were biopsied with 18-gauge cutting needles, guided by ultrasound, and sent for histopathological analysis. The ultrasonographic ch.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.7
DOI:
http://dx.doi.org/10.4238/2015.April.22.7
Medical Genetics   Research Article

microRNAs in avian influenza virus H9N2-infected and non-infected chicken embryo fibroblasts

Authors: X. Peng, Q.S. Gao, L. Zhou, Z.H. Chen, S. Lu, H.J. Huang, C.Y. Zhan and M. Xiang

There is limited information about microRNAs (miRNAs) in H9N2 subtype influenza virus-infected chicken cells or tissues. In this study, 10,487,469 and 13,119,795 reads were obtained from infected and non-infected chicken embryo fibroblasts, respectively. Seven hundred and thirty-six and 1004 miRNAs, including mature miRNAs and precursors, were obtained fr.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.17
DOI:
10.4238/2015.August.7.17
Medical Genetics   Research Article

Preoperative computed tomography-guided hook-wire positioning of pulmonary nodules

Authors: W. Li,C.B. Zhai,Y.J. Guan,L.J. Jing,Z.L. Zhang and X.H. Zhao

This study aimed to analyze the clinical application value of computed tomography (CT)-guided hook-wire positioning before thoracoscopic surgery. Eighty-four patients who had received a thoracoscopic wedge resection of pulmonary nodules between January and December 2013 were selected. Group A consisted of 38 cases where the hook-wire positioning technique.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.9
DOI:
http://dx.doi.org/10.4238/2015.April.22.9
Medical Genetics   Research Article

Application of DNA barcoding markers to the identification of Hopea species

Authors: Nguyen T.P. Trang, N.M. Duc, N.V. Sinh and L. Triest

Hopea chinensis (synonym: H. hongayensis) (Dipterocarpaceae) is a threatened species found so far in only two locations: Quang Ninh (Vietnam) and Guangxi (China). The species shares many morphological characteristics with H. mollissima and the two species are often confused. To overcome this problem of identification and to investigate the genetic relatio.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.28
DOI:
10.4238/2015.August.7.28