Medical Genetics
Identification of a new locus conferring antixenosis to the brown planthopper in rice cultivar Swarnalata (Oryza sativa L.)
Authors: Y.F. Qiu, L. Cheng, F. Liu and R.B. Li
The brown planthopper [Nilaparvata lugens (Stål); BPH] has caused severe damage to rice production. The identification of resistance genes and the development of BPH-resistant varieties are economical and effective ways to manage this pest. Using an F2 population from a cross between the Indica cultivars 93-11 and Swarnalata, we mapped the Qbph-8 lo.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.29.4
- DOI:
- 10.4238/2013.August.29.4
Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene
Authors: L.J. Duan and X.D. Wang
This study aimed to explore correlations between haplotypes of the angiotensin II receptor type 1 (AGTR1) gene and coronary heart disease (CHD). In total, 204 patients with CHD and 206 healthy controls were genotyped using denaturing high-performance liquid chromatography between 2008 and 2014. Five polymorphic loci were found.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017457
- DOI:
- 10.4238/gmr.15017457
Isolation and characterization of novel microsatellite markers in Mercenaria mercenaria
Authors: Y.F. Ning, Z.B. Li, X.Q. Mao, B.B. Li, Y.S. Huang, Y. Yuan and J.B. Shangguan
Mercenaria mercenaria, also known as the hard clam, is widely distributed in the coastal waters of temperate and tropical areas in the Asian Pacific region. This species is widely popular in the international market, especially in the United States, Europe, and other Western countries, because of its high protein value, taste,.. Read More»
- Genet. Mol. Res. 14(1):
- gmr.15017497
- DOI:
- 10.4238/gmr.15017497
All-trans retinoic acid prevents the development of type 1 diabetes by affecting the levels of interferon gamma and interleukin 4 in streptozotocin-induced murine diabetes model
Authors: Y. Wang, Y.J. Zhong, Y.Y. Wang, J. Xing and Z.M. Wang
The aim of this study was to explore the molecular mechanism by which all-trans retinoic acid (ATRA) prevents type 1 diabetes mellitus (T1DM). Fifty ICR mice were randomly assigned to three groups: prevention group [N = 20; mice received 10 mg/kg ATRA daily for 5 days and then 60 mg/kg streptozotocin (STZ) for 5 days]; diabeti.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017522
- DOI:
- 10.4238/gmr.15017522
A fast and simple method for the polymerase chain reaction-based sexing of livestock embryos
Authors: K.C.S. Tavares, I.S. Carneiro, D.B. Rios, C. Feltrin, A.K.C. Ribeiro, S. Gaud?ªncio-Neto, L.T. Martins, L.H. Aguiar, C.R. Lazzarotto, C.E.M. Calder?³n, F.E.M. Lopes, L.P.R. Teixeira, M. Bertolini and L.R. Bertolini
Embryo sexing is a powerful tool for livestock producers because it allows them to manage their breeding stocks more effectively. However, the cost of supplies and reagents, and the need for trained professionals to biopsy embryos by micromanipulation restrict the worldwide use of the technology to a limited number of speciali.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017476
- DOI:
- 10.4238/gmr.15017476
Assessment of clinical scoring systems for the diagnosis of Williams-Beuren syndrome
Authors: D.E.S. Leme, D.H. Souza, G. Mercado, E. Pastene, A. Dias and D. Moretti-Ferreira
Williams-Beuren syndrome (WBS) is a genetic disorder characterized by physical and intellectual developmental delay, associated with congenital heart disease and facial dysmorphism. WBS is caused by a microdeletion on chromosome 7 (7q11.23), which encompasses the elastin (ELN) gene and about 27 other genes. The gold standard for WBS laboratory diagnosis i.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.7
- DOI:
- 10.4238/2013.September.4.7
Significance of TNF-?± and IL-6 expression in invasive pituitary adenomas
Authors: J.L. Wu, J.Y. Qiao and Q.H. Duan
The aim of this study was to investigate expression of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in invasive pituitary adenomas (IPAs). The streptavidin peroxidase immunohistochemical method was employed to detect their expression in 40 cases of IPA and 40 of non-invasive pituitary adenoma (NIPA). TNF-α and IL-6 were found.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017502
- DOI:
- 10.4238/gmr.15017502
Reply to commentary by G. Sikri and S. Dua on the article â??Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edemaâ? published in Genetics and Molecular Research 14 (3): 11562-11572 to the letter published in Genet. Mol. Res. 14 (4): 15904-15905
Authors: L.J. Wu
The object in this study was a Han Chinese population in Lhasa, with 3658 m in altitude from Chengdu, which has 505 m in altitude by air. Within 24 to 48 h before the subjects arrived in the plateau, they completed a basic situation questionnaire, under the guidance of medical staff. Within 24 to 48 h after they reached the plateau, the subjects completed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016155
- DOI:
- 10.4238/gmr.15016155
Correlation between serum IL-16 and atopic dermatitis
Authors: H.Y. Zheng, L. Zhao, C.X. Li and S.H. Li
This study aims to investigate the correlation between allergic sensitization of atopic dermatitis (AD) patients and their serum interleukin (IL)-16 levels. AD patients, healthy volunteers, and patients with psoriasis (N = 80, 35, 20, respectively) were tested for serum IL-16 and total and specific IgE levels by enzyme-linked .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016556
- DOI:
- 10.4238/gmr.15016556
Spermiotaxonomy of the tribe Rhodniini (Hemiptera, Triatominae)
Authors: A. Ravazi, J. Oliveira, J.A. Rosa, M.T.V. Azeredo-Oliveira and K.C.C. Alevi
The tribe Rhodniini is a monophyletic group composed of 22 species, with 19 in the Rhodnius genus and three in the Psammolestes genus. These insects are morphologically very similar (cryptic species), and new tools are important for investigating the taxonomy of these vectors. Spermiotaxonomy is an important tool in differentiating between related species.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017366
- DOI:
- 10.4238/gmr.15017366