Medical Genetics
Analysis of an â??off-ladderâ? allele at the Penta D short tandem repeat locus
Authors: Y.L. Yang, J.G. Wang, D.X. Wang, W.Y. Zhang, X.J. Liu, J. Cao and S.L. Yang
Kinship testing of a father and his son from Guangxi, China, the location of the Zhuang minority people, was performed using the PowerPlex® 18D System with a short tandem repeat typing kit. The results indicated that both the father and his son had an off-ladder allele at the Penta D locus, with a genetic size larger than .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.18
- DOI:
- 10.4238/2015.November.24.18
Detection of CK19, LUNX, and KS1/4 mRNA expression in the peripheral blood for diagnosis of micrometastases in patients with non-small cell lung cancer and their clinical implications
Authors: L. Yan, Y. Yao, L.H. Wang, M.L. Wang and X.H. Fu
The expression of CK19, LUNX, and KS1/4 mRNA biomarkers was detected in the peripheral blood of non-small cell lung cancer (NSCLC) patients to investigate the feasibility of indicating lung cancer micrometastases. Micrometastases were identified in the peripheral blood of 32 NSCLC patients, 15 benign pulmonar.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.17
- DOI:
- 10.4238/2015.November.24.17
An elevated plasma level of visfatin increases the risk of myocardial infarction
Authors: Y. Yang1, Z. Li2, H.F. Tao1, X.Y. Qi1, W.L. Wang1, L. Yang1, H. Wang1 and P. Xu1
Visfatin, an adipocytokine involved in metabolic and immune disorders, plays an important role in the etiology of cardiovascular disease. Recent evidence has shown that an elevated plasma level of visfatin may increase the risk of myocardial infarction (MI), but individual published studies have shown inconclusive results. This study aimed to obtain a mor.. Read More»
- Genet. Mol. Res. 13(4):
Genetic diversity and phylogeny of rhizobia isolated from Caragana microphylla growing in desert soil in Ningxia, China
Authors: J. Dai, X. Liu and Y. Wang
Rhizobia are soil bacteria with the capacity to induce nitrogen-fixing nodules on the roots or stems of legume plants. A total of 40 bacterial isolates from the root nodules of Caragana microphylla growing in desert soil in Ningxia, China, were analyzed for genetic diversity and phylogenetic position. These isolates were classified into 7 types of 16S rib.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.25.5
- DOI:
- 10.4238/2012.June.25.5
Anatomical information for intercostobrachial nerve preservation in axillary lymph node dissection for breast cancer
Authors: J.J. Zhu1*, X.F. Liu1, P.L. Zhang1, J.Z. Yang1, J. Wang2, Y. Qin1, G.L. Zhang1, D.Q. Ren1, C.L. Cui3 and X.G. Guo1*
This study aimed to provide additional anatomical information for axillary lymph node dissection (ALND) through in vivo anatomy studies of intercostobrachial nerve (ICBN) preservation in order to provide theoretical and practical experience for clinicians. A total of 156 patients with breast cancer underwent ALND at the Department of Gynecology of Baotou Tum.. Read More»
- Genet. Mol. Res. 13(4):
Nerve growth factor regulates the expression of vascular endothelial growth factor in human HaCaT keratinocytes via PI3K/mTOR pathway
Authors: J. Zhang1 and W.Y. Ma2
Decades of research have provided the data to confirm the hypothesis that there is bidirectional communication between the central nervous system and the immune system in psoriasis pathogenesis, but the contribution of the cutaneous neural system remains underexplored. In this study, we evaluated the molecular mechanisms by which nerve growth factor (NGF).. Read More»
- Genet. Mol. Res. 13(4):
Molecular characterization and functional analysis of sheep thyroid transcription factor-1
Authors: L.P. Zhang, B.Y. Ma*, F.X. Han, H.L. Wan, J.P. Wu, L.H. Yu, X.R. Wang and J.Y. Zhu
Thyroid transcription factor-1 (TTF-1), a member of the Nkx2 family of homeodomain-containing proteins, is involved in binding to and in activating the promoters of several important genes in the thyroid, lungs, and brain, and in regulating expression of these tissue-specific genes. We investigated potential roles of sheep (Ovis aries) TTF-1 in regulating.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.18.2
- DOI:
- 10.4238/2012.June.18.2
Impact of methylenetetrahydrofolate reductase polymorphisms and folate intake on the risk of gastric cancer and their association with Helicobacter pylori infection and tumor site
Authors: J. Chen1, L. Yuan1, Y.Q. Duan1, J.Q. Jiang3, R. Zhang1, Z.J. Huang2 and X.R. Xiao1
Folic acid and methylenetetrahydrofolate reductase (MTHFR) may both affect the development of human cancer. We conducted a population-based case-control study in a Chinese population to investigate the potential role of folate intake and MTHFR gene polymorphisms in gastric cancer, and their interaction with infection by Helicobacter pylori and tumor locat.. Read More»
- Genet. Mol. Res. 13(4):
Association of the FTO gene SNP rs17817449 with body fat distribution in Mexican women
Authors: J.J. Zerme?±o-Rivera1, J.P. Astocondor-P?©rez1, Y. Valle2, J.R. Padilla-Guti?©rrez2, R. Orozco-Castellanos3,4, L.E. Figuera5,6 and B.E. Guti?©rrez-Amavizca5,6
Polymorphisms in the FTO gene are associated with obesity, body mass index, hip circumference, and visceral and subcutaneous fat area. The objective of this study was to analyze the association of the FTO rs17817449 genetic variant (T>G polymorphism) with body fat distribution patterns in women. We included 65 women and 71 healthy subjects in this stud.. Read More»
- Genet. Mol. Res. 13(4):
Role of survivin in the pathogenesis of papillary thyroid carcinoma
Authors: J.Y. Li, J. Shi, J.F. Sang, Y.Z. Yao, X.C. Wang and L. Su
The purpose of this study was to assess the correlation between the survivin gene and the occurrence and pathogenesis of papillary thyroid carcinoma (PTC). Sixty patients with PTC and no preoperative chemotherapy were recruited for the study and 30 thyrophyma patients receiving operative treatment in Drum Tower Hospital (Nanji.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.19
- DOI:
- 10.4238/2015.November.24.19