Human Genetics
Sub-lethal doses of neonicotinoid and carbamate insecticides reduce the lifespan and alter the expression of immune health and detoxification related genes of honey bees (Apis mellifera)
Authors: Hassan Tarek, Mollah Md. Hamiduzzaman, Nuria Morfin and Ernesto Guzman-Novoa
Honey bees (Apis mellifera) are exposed to sublethal doses of insecticides, but little is known about insecticide effects on their survivorship associated to health-related gene expression. To test the effect of sublethal doses of clothianidin, imidacloprid and carbaryl on the lifespan and health of honey bees, workers were or.. Read More»
- Genet. Mol. Res. 17(2):
- gmr16039908
- DOI:
- 10.4238/gmr16039908
The effect of acetate Ringer's solution on inflammatory factors and NF-�ºB signal pathway in the liver of hemorrhagic shock rats
Authors: Z. P. Xu�Q. Song�Z. L. Qiu�L. Li�Z. H. Du and Z. J. Wang
Purpose: To investigate the effect of resuscitation with acetated Ringer's solution during hemorrhagic shock (HS) on inflammatory factors and nuclear factor κB (NF-κB) signaling pathway in liver tissue. Methods: In this study, a rat HS model was established. HS rats received acetated Ringer's solution, lactated Ringer's solution and saline for.. Read More»
- Genet. Mol. Res. 17(2):
- gmr16039906
- DOI:
- 10.4238/gmr16039906
Identification of Clematidis radix et Rhizoma and its adulterants by core haplotype based on the ITS sequences
Authors: Yi-Mei Zang, Ya Gao, Ying Liu, Chun-Sheng Liu
To develop a method to identify Clematidis radix et Rhizoma using sequence similarity and sequence-specific genetic polymorphisms based on the ITS sequences. DNA was extracted from leaves of Clematis mandshurica Rupr and C. hexapetala using a DNA extraction kit. ITS sequences were amplified by PCR, and analyzed in Contig Expre.. Read More»
- Genet. Mol. Res. 17(2):
- gmr16039905
- DOI:
- 10.4238/gmr16039905
Patient�s adherence to prescribed home exercises: Barriers and interventions
Authors: Soukayna Mourad, Hassane Kheir Eddine, Hassan Karaki, Khodor Haidar Hassan
Purpose: The purpose of this study is to evaluate patients’ adherence to home exercise programs in physical therapy practice in Lebanon, to learn which factors determine the level of adherence, and the methods used to promote it. Materials and methods: An online questionnaire was sent to a random group of Lebanese physic.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039898
- DOI:
- 10.4238/gmr16039898
New tool application in veterinary forensic science to analyze genetic fingerprinting data
Authors: Reale S, Mascali LG, Bonanno , Lupo, Ferina , Vitale
In the last decades legal and other cases in which forensic veterinary science is required are increasing. The principles of investigation follow those used in human beings, although in animal species familial relationship identification is a hard task, due to high level of inbreeding. Familias 3 software is commonly used in h.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039893
- DOI:
- 10.4238/gmr16039893
Screening and identification of candidate genes essential for cervical lymph node metastasis in nasopharyngeal carcinoma with microarrays
Authors: Ming Fu, Yudong Ye, Chi Zhang, Zhuo Chen, Zhenchao Zhu, Yang Peng, Xiangning Zhang, Qianhui Qiu
The aim of the present study is to identify genes that are crucial for the cervical lymph node metastasis, which predicts poor prognosis of nasopharyngeal carcinoma (NPC), endemic in southern China. Microarrays with probes to determine genomic expression profile and promoter methylation status in tumor specimens were used, to .. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039892
- DOI:
- 10.4238/gmr16039892
Genetic Polymorphism in Endometriosis: Trends in Scientific Production
Authors: Maria Gabriela Machado Junqueira, Amanda Fernandes Costa, Felipe de Ara�ºjo Nascimento, K�¡tia Karina Verolli de Oliveira Moura, Fl�¡via Melo Rodrigues
Endometriosis is characterized by the presence of endometrial tissue located outside the uterine cavity. The prevalence is around 6 to 10%. Regarding etiopathogenesis, several theories are accepted, but alterations in the molecular biology of the endometrium seem to be fundamental for the development of endometriosis. Women wi.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039891
- DOI:
- 10.4238/gmr16039891
Predominance of the A allele but no association of the KCNJ11 rs5219 E23K polymorphism with Type 2 Diabetes in a Nigerian population
Authors: Godwill Azeh Engwa, Friday Nweke Nwalo, Chosen E. Obi, Christie Onyia, Opeolu Oyejide Ojo Wilfred Fon Mbacham, Benjamin Ewa Ubi
Though the rs5219 E23K variant of the KCNJ11 gene is commonly known to be associated with Type 2 diabetes (T2D) in Caucasian and Asian populations, little or none of such findings have been revealed in Nigeria. Hence, this study was aimed to assess the relationship between E23K polymorphic variant of the KCNJ11 gene and T2D in.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039889
- DOI:
- 10.4238/gmr16039889
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells
Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri
Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039888
- DOI:
- 10.4238/gmr16039888
Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit
Authors: Magnus Dencker, Ylva G�¥rdinger, Ola Bj�¶rgell, Joanna Hlebowicz
Objectives: The present study evaluates the effect of food intake on 90 biomarkers for cardiovascular disease (CVD) and inflammation with the Proseek Multiplex CVD II kit. Methods: Twenty-two healthy subjects (11 male and 11 females aged 25.9±4.2 years) were investigated. A total of 90 biomarkers were measured before a .. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039884
- DOI:
- 10.4238/gmr16039884