Human Genetics
Correlation between the development of calcium oxalate stones and polymorphisms in the fibronectin gene in the Uighur population of the Xinjiang region of China
Authors: M. Murat, A. Aekeper, L.Y. Yuan, T. Alim, G.J. Du, A. Abdusamat,G.W. Wu and Y. Aniwer
Here, we have investigated the correlation between calcium oxalate stone formation and Fn gene polymorphisms in urinary calculi patients among the Uighur population (Xinjiang region). In this case control study, genomic DNA extracted from the peripheral blood of 129 patients with calcium oxalate stones (patient group) and 94 normal people (control group) .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.35
- DOI:
- 10.4238/2015.October.28.35
RETRACTION of â??Immune memory responses to HBV vaccine 13-18 years after primary vaccinationâ? by L. Hou, W. Li, X. Wei, Y. Zhou, Y. Zhuo, H. Wu, B. Shen. Genet. Mol. Res. 14 (3): 8466-8472 (2015)
Authors: .
The article “Immune memory responses to HBV vaccine 13-18 years after primary vaccination” by L. Hou, W. Li, X. Wei, Y. Zhou, Y. Zhuo, H. Wu, B. Shen published in 2015 in Genetics and Molecular Research 14(3): 8466-8472 (http://dx.doi.org/10.4238/2015.July.28.14) has been found to be substantially equal to the article “Immune memory resp.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.150159121
- DOI:
- 10.4238/gmr.150159121
Corrigendum: Association between TAP1 gene polymorphisms and alopecia areata in a Korean population - Genet. Mol. Res. 14 (4): 18820-18827
Authors: H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6
H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. Lee3, S. Lee4, I.H. Cho5, J.T. Kwon1 and H.J. Kim1,6 5Department of Convergence Medical Science, Brain Korea 21 Plus Program, and Institute of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea H.K. Kim1*, H. Lee1*, B.L. Lew2, W.Y. Sim2, Y.O. Kim3, S.W. .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.150170751
- DOI:
- 10.4238/gmr.150170751
Lenalidomide affect expression level of cereblon protein in multiple myeloma cell line RPMI8226
Authors: D.Y. Yang, J.H. Ren, X.N. Guo, X.L. Guo, X.Y. Cai, X.F. Guo and J.N. Zhang
We investigated the mechanisms of action of immunomodulatory drug (lenalidomide) on the protein expression of cereblon (CRBN) and their therapeutic targets in the multiple myeloma cell line RPMI8226. The multiple myeloma cell line RPMI8226 was cultured and treated with different concentrations of lenalidomide and bortezomib to determine the proliferation .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.19
- DOI:
- 10.4238/2015.October.28.19
An alternate method for DNA and RNA extraction from clotted blood
Authors: Z. Zakaria S.H. Umi S.S. Mokhtar U. Mokhtar M.Z. Zaiharina A.T.A. Aziz B.P. Hoh
We developed an alternative method to extract DNA and RNA from clotted blood for genomic and molecular investigations. A combination of the TRIzol method and the QIAamp spin column were used to extract RNA from frozen clotted blood. Clotted blood was sonicated and then the QIAamp DNA Blood Mini Kit was used for DNA extraction. Extracted DNA and RNA were a.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.4.4
- DOI:
- 10.4238/2013.February.4.4
Association analysis of rs2275913G>A and rs763780T>C interleukin 17 polymorphisms in Chinese women with cervical cancer
Authors: L.X. Sun, X.B. Wang and X.J. Huang
We conducted a case-control study with a relatively large sample size, and investigated the association between rs2275913G>A and rs763780T>C and the risk of cervical cancer. Three hundred and six newly diagnosed patients with histologically confirmed cervical cancer and 354 cancer-free control subjects were recruited from the Forestry General Hospit.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.22
- DOI:
- 10.4238/2015.October.28.22
5-Aza-2â??-deoxycytidine may influence the proliferation and apoptosis of cervical cancer cells via demethylation in a dose- and time-dependent manner
Authors: T.T. Yao S.M. Mo L.Y. Liu H.W. Lu M.L. Huang Z.Q. Lin
The methylation of tumor suppressor genes has been shown to be involved in many human cancers. 5-Aza-2’-deoxycytidine (5-Aza-CdR) can reactivate the expression of methylated tumor suppressor genes. In our study, 2 human cervical cancer cell lines, HeLa and SiHa, were treated with different concentrations (20, 10, 5, and 2.5 μM) of 5-Aza-CdR for 2.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.4.5
- DOI:
- 10.4238/2013.February.4.5
Gene silencing during development ofin vitro-produced female bovine embryos
Authors: G.K.F. Merighe, F.H. Biase, W.K.F. Santos-Biase, M.S. Miranda,T.H.C. de Bem, Y.F. Watanabe and F.V. Meirelles
In early development, female embryos (XX) produce twice the transcripts of X-linked genes compared with male embryos (XY). During the course of development, inactivation of the X chromosome equilibrates gene dosage, making the development of female embryos viable. Moreover, the biotechnologies used for producing embr.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr638
- DOI:
- 10.4238/vol8-3gmr638
Somatic copy-neutral loss of heterozygosity and copy number abnormalities in Malaysian sporadic colorectal carcinoma patients
Authors: Y.Y. Yam B.P. Hoh N.H. Othman S. Hassan M.M. Yahya Z. Zakaria R. Ankathil
Colorectal cancer is one of the most common cancers in many countries, including Malaysia. The accumulation of genomic alterations is an important feature of colorectal carcinogenesis. A better understanding of the molecular events underlying the stages of colorectal carcinogenesis might be helpful in the detection and management of the disease. We used a.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.7.1
- DOI:
- 10.4238/2013.February.7.1
RAPD-based study of genetic variation and relationships among wild fig genotypes in Turkey
Authors: M. Akbulut, S. Ercisli and H. Karlidag
The fig tree (Ficus carica L.) is of significant socio-economic importance in Turkey, with 25% of the world’s fig production. Genetic variation and relationships among 14 wild-grown figs sampled from Coruh Valley in Turkey were characterized by random amplified polymorphic DNA (RAPD). Ninety-eight DNA fragments were scor.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr634
- DOI:
- 10.4238/vol8-3gmr634