Human Genetics
Modified Da Chengqi granules improvement in immune function in early severe acute pancreatitis patients
Authors: D.-L. Jiang, J. Yang, S.-Y. Jiang, F.-L. Yuan, Y.-L. Gu, J.-P. Li and Z.-J. Pei
We investigated the role of modified Da Chengqi granules in improving immune function in early severe acute pancreatitis patients. Early severe acute pancreatitis patients who agreed to receive combined treatment of traditional Chinese and Western medicine were randomly assigned to the experimental or control group. All subjec.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028787
- DOI:
- 10.4238/gmr.15028787
Multiple sequence alignment based on combining genetic algorithm with chaotic sequences
Authors: C. Gao, B. Wang, C.J. Zhou and Q. Zhang
In bioinformatics, sequence alignment is one of the most common problems. Multiple sequence alignment is an NP (nondeterministic polynomial time) problem, which requires further study and exploration. The chaos optimization algorithm is a type of chaos theory, and a procedure for combining the genetic algorithm (GA), which use.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028788
- DOI:
- 10.4238/gmr.15028788
Daidzein promotes osteoblast proliferation and differentiation in OCT1 cells through stimulating the activation of BMP-2/Smads pathway
Authors: B. Hu, B. Yu, D. Tang, S. Li and Y. Wu
Daidzein, the most widely studied soy phytoestrogen, is not only a potential antiosteoporosis agent owing to its possible osteogenic activity, but also shows anticancer activity. However, the mechanisms through which daidzein affects osteoblast function have not been investigated thoroughly. Here, we show that daidzein stimula.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028792
- DOI:
- 10.4238/gmr.15028792
Mechanism underlying the bio-effects of an electromagnetic field based on the Huang-Ferrell model
Authors: D.Y. Geng, G. Hu, L. Wang, N. Jia and F.X. Wang
To understand the beneficial and harmful bio-effects of extremely low frequency electromagnetic fields, we studied the MAPK/ERK signaling pathway based on the Huang-Ferrell model. The sensitivity analysis method was used to study the influence of the model parameters on the activity of ERK, and to further investigate the key b.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028796
- DOI:
- 10.4238/gmr.15028796
Genetic characterization of red-colored heartwood genotypes of Chinese fir using simple sequence repeat (SSR) markers
Authors: H.J. Duan, R.Y. Hu, B. Wu, D.X. Chen, K.Y. Huang, J. Dai, Q. Chen, Z.C. Wei, S. Cao, Y.H. Sun and Y. Li
The present study investigated the genetic characterization of red-colored heartwood Chinese fir [Cunninghamia lanceolata (Lamb.) Hook.] in Guangxi using 21 simple sequence repeat (SSR) markers and analyzes of the genetic variation (N = 149) in samples obtained from five sites in Guangxi Province, China. The number of different alleles and the Shannon&rsq.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.2
- DOI:
- 10.4238/2015.December.28.2
Applying the Fisher score to identify Alzheimer�s disease-related genes
Authors: J. Yang, Y.L. Liu, C.S. Feng and G.Q. Zhu
Biologists and scientists can use the data from Alzheimer's disease (AD) gene expression microarrays to mine AD disease-related genes. Because of disadvantages such as small sample sizes, high dimensionality, and a high level of noise, it is difficult to obtain accurate and meaningful biological information from gene expressio.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028798
- DOI:
- 10.4238/gmr.15028798
A simple real-time polymerase chain reaction (PCR)-based assay for authentication of the Chinese Panax ginseng cultivar Damaya from a local ginseng population
Authors: H. Wang, J. Wang2 and G. Li
Panax ginseng is one of the most important medicinal plants in the Orient. Owing to its increasing demand in the world market, cultivated ginseng has become the main source of medicinal material. Among the Chinese ginseng cultivars, Damaya commands higher prices and is grown in significant proportions among the local ginseng p.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028801
- DOI:
- 10.4238/gmr.15028801
Relevance of sampling and DNA extraction techniques for the analysis of salivary evidence from bite marks: a case report
Authors: M.L. ChÃ?¡vez-Briones, R. HernÃ?¡ndez-CortÃ?©s, G. Jaramillo-Rangel and M. Ortega-MartÃ?Ânez
Bite mark evidence has been repeatedly found in criminal cases. Physical comparison of a bite mark to the teeth of available suspects may not always be possible. Experimental studies have shown that the analysis of DNA present in the saliva recovered from bite marks might help in the identification of individuals. However, the application of this approach.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.23
- DOI:
- 10.4238/2015.August.21.23
Levels of mannose-binding lectin in individuals with visceral leishmaniasis in the northeast region of Brazil
Authors: E.L. da Silva, M. Campos J�ºnior, S.G. Monteiro, G.C. Costa, A.L.P. Magalh�£es, M.D.C. Santos, A.J.M. Caldas and M.M.G. Pimentel
Visceral leishmaniasis (VL) is one of the seven priority endemic diseases in the world. The clinical outcome of many infections is not only dependent on the pathogenic organism, but also on the genetic variability of the host susceptibility to infection. Mannose-binding lectin (MBL) is a protein that plays an important role in the innate immune system. Th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.18
- DOI:
- 10.4238/2015.December.29.18
Differential expression of luteinizing hormone receptor, androgen receptor and heat-shock protein 70 in the testis of long-distance transported mice
Authors: L.P. Sun, Y.P. Song, J.J. Liu, X.R. Liu, A.Z. Guo and L.G. Yang
Spermatogenesis, is a complex process of precisely regulated intracellular events, where it is affected by many factors. Long-distance transport of animals is one of the stressors that may influence spermatogenesis and sperm quality. The present study chose luteinizing hormone receptor (LHR), androgen receptor (AR), and heat-shock protein 70 (HSP70) as ou.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.4
- DOI:
- 10.4238/2015.August.21.4