Human Genetics
Genetic diversity of the Arctic fox using SRAP markers
Authors: M. Zhang1 and X.J. Bai2
Sequence-related amplified polymorphism (SRAP) is a recently developed molecular marker technique that is stable, simple, reliable, and achieves moderate to high numbers of codominant markers. This study is the first to apply SRAP markers in a mammal, namely the Arctic fox. In order to investigate the genetic diversity of the .. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.4.4
- DOI:
- 10.4238/2013.December.4.4
Determination of the genetic diversity among accessions of Senna spectabilis (canafÃ?Âstula) by using RAPD markers
Authors: M.F. Santos1, R.B. Ara�ºjo Neto2, M.P.S.B.C. Nascimento2 and P.S.C. Lima2
Senna spectabilis (DC.) H.S. Irwin & Barneby (Fabaceae; Caesalpinioideae), commonly known as “canafístula” or “cassia”, is widely used in the semi-arid region of northeastern Brazil as a source of forage and timber. The plant presents a high nutritional content in comparison with other forage species that are native to t.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.2.12
- DOI:
- 10.4238/2013.December.2.12
Association of the CYP1A1 MspI and TNF�±-308 polymorphisms with chronic obstructive pulmonary disease in Inner Mongolia
Authors: L. Yang, F. Li2*, M. Yan and X. Su
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by persistent airflow limitation. Smoking, occupational exposures, air pollution, and genetics are all risk factors. In the present study, we detected the cytochrome P4501A1 gene (CYP1A1) MspI polymorphism and the tumor necrosis factor alp.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.25.6
- DOI:
- 10.4238/2014.April.25.6
Expression profiles of variation integration genes in bladder urothelial carcinoma
Authors: J.M. Wang, Y.Q. Wang, Z.L. Gao, J.T. Wu, B.K. Shi and C.C. Yu
Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.9
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.9
Proteins differentially expressed by Shiga toxin-producing Escherichia coli strain M03 due to the biliar salt sodium deoxycholate
Authors: C.B.A. Ribeiro1, M.G. Sobral1, C.L. Tanaka1, C.B. Dallagassa1, G. Picheth1, F.G.M. Rego1, D. Alberton1, L.F. Huergo2, F.O. Pedrosa2, E.M. Souza2 and C.M.T. Fadel-Picheth1
Shiga toxin-producing Escherichia coli (STEC) can cause conditions ranging from diarrhea to potentially fatal hemolytic uremic syndrome. Enteropathogen adaptation to the intestinal environment is necessary for the development of infection, and response to bile is an essential characteristic. We evaluated the response of STEC strain M03 to the bile salt so.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.1
- DOI:
- 10.4238/2013.October.24.1
Geographical genetics of Pseudoplatystoma punctifer (Castelnau, 1855) (Siluriformes, Pimelodidae) in the Amazon Basin
Authors: M.P.C. Telles, R.G. Collevatti, R.S. Braga, L.B.S. Guedes, T.G. Castro, M.C. Costa, N.J. Silva-J�ºnior, R.B. Barthem and J.A.F. Diniz-Filho
Geographical genetics allows the evaluation of evolutionary processes underlying genetic variation within and among local populations and forms the basis for establishing more effective strategies for biodiversity conservation at the population level. In this study, we used explicit spatial analyses to investigate molecular ge.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.8
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.8
Genetic association of catechol-O-methyltransferase val(158)met polymorphism in Saudi schizophrenia patients
Authors: S. Al-Asmary, S. Kadasah, M. Arfin, M. Tariq and A. Al-Asmari
Schizophrenia is a complex neuropsychiatric disorder strongly associated with dopamine dysregulation. Catechol-O-methyl-transferase (COMT) is a candidate gene for schizophrenia that encodes an enzyme involved in the metabolic inactivation of dopamine. The COMT Val158Met polymorphism has been associated with schizophrenia and h.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.4
- DOI:
- 10.4238/2014.April.17.4
Optimum conditions for inducing laccase production in Lentinus crinitus
Authors: J.S. Valle1,2, L.P.S. Vandenberghe2, T.T. Santana1, P.H. Almeida1, A.M. Pereira1, G.A. Linde1, N.B. Colauto1 and C.R. Soccol2
Laccases are environmentally friendly alternatives in many important applications such as in bioremediation, biopulping, textile, and the food industry. They have wide substrate specificity, can oxidize a broad range of compounds, and show potential for use in various industrial processes. Therefore, developing methods to increase laccase production is im.. Read More»
- Genet. Mol. Res. 13(4):
Role of XRCC1 and ERCC5 polymorphisms on clinical outcomes in advanced non-small cell lung cancer
Authors: D. Liu, J. Wu, G.Y. Shi, H.F. Zhou and Y. Yu
We aimed to assess the role of polymorphisms of the XRCC1 Arg194Trp, XRCC1 Arg399Gln, ERCC5 His1104Asp, and ERCC5 His46His genes on clinical outcomes of advanced non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy regimens. A total of 378 NSCLC patients were asked to participate within 1 month aft.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.6
- DOI:
- 10.4238/2014.April.17.6
Registries of cases with neural tube defects in Denizli, Turkey, 2004-2010
Authors: A.G. Tomatir1, B. Kiray Vural2, I. Acikbas1 and B. Akdag3
Neural tube defects (NTD) are among the most common congenital abnormalities, with an incidence of 3 per 1000 live births in Turkey. In a study of major congenital abnormalities in the city of Denizli, Turkey, abnormalities of the central nervous system are particularly common (31.1%). The objective of this study was to develop a registry of cases with NT.. Read More»
- Genet. Mol. Res. 13(4):