Cytogenomics
Role of a homozygous A(TA)7TAA promoter polymorphism and an exon 1 heterozygous frameshift mutation UGT1A1 in Crigler-Najjar syndrome type II in a Thai neonate
Authors: P. Nilyanimit, A. Krasaelap, M. Foonoi, V. Chongsrisawat and Y. Poovorawan
Crigler-Najjar syndrome is a rare autosomal recessive disease caused by mutations in the UGT1A1 gene. These mutations result in the deficiency of UGT1A1, a hepatic enzyme essential for bilirubin conjugation. This report describes the case of a 4-month-old boy with the cardinal symptoms of Crigler-Najjar syndrome type II. Molecular genetic analysis showed .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.5
- DOI:
- 10.4238/2013.September.4.5
Effect of muscle-fiber type on glycogenin-1 gene expression and its relationship with the glycolytic potential and pH of pork
Authors: S.-H. Zhang, L. Zhu, Z.-H. Wu, Y. Zhang, G.-Q. Tang, Y.-Z. Jiang, M.-Z. Li, L. Bai and X.-W. Li
This study analyzed the effect of muscle-fiber type composition on glycogenin-1 (GYG) gene expression and its impact on pH. The longissimus dorsi (LD) muscle contains more type IIB fibers (75.10%) than does the psoas major (PM) muscle (41.58%), while the PM has more type I (3.65 vs 0.94%), type IIA (34.15 vs 10.63%), and type IIX (20.62 vs 13.33%) fibers... Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.4
- DOI:
- 10.4238/2013.September.4.4
Association between a polymorphism of the �±-lactalbumin gene and milk production traits in Chinese Holstein cows
Authors: J.P. Zhou and C.H. Dong
The traits particularly important for milk production include milk yield, protein percentage, fat percentage, and the somatic cell score. Alpha-lactalbumin (α-LA) is an important whey protein of cow milk, and is also present in the milk of many other mammalian species. In this study, we analyzed the genetic polymorphisms of the α-LA gene and t.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.3
- DOI:
- 10.4238/2013.September.4.3
Lignocellulolytic enzymes and bacteria associated with the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae
Authors: R. Koroiva, C.W.O. Souza, D. Toyama, F. Henrique-Silva and A.A. Fonseca-Gessner
We analyzed the digestive activity of the enzymes that digest cellulose and hemicellulose and the bacterial community that is capable of hydrolyzing wood compounds in the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae, which are miners of decomposing submerged tree and bush branches. Based on quantification of reducing sugars, these la.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.April.2.2
- DOI:
- 10.4238/2013.April.2.2
Gene expression patterns of invertase gene families and modulation of the inhibitor gene in tomato sucrose metabolism
Authors: Y.L. Zhang, A.H. Zhang and J. Jiang
Patterns of gene expression in the different types of sucrose metabolism in the tomato are highly variable and heritable. This genetic variation causes considerable functional differences. We examined the patterns of expression of invertase (Inv) gene families and an invertase inhibitor (INH) gene involved in elongating roots, hypocotyls, and fruit of the.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.24.1
- DOI:
- 10.4238/2013.January.24.1
Effect of atorvastatin on left atrial function of patients with paroxysmal atrial fibrillation
Authors: Y.D. Li, B.P. Tang, F. Guo, J.X. Li, W. Han, Q. Tang and Y.Y. Zhang
The aim of this study was to evaluate the effects of atorvastatin on left atrial (LA) function in paroxysmal atrial fibrillation patients. Fifty-eight paroxysmal atrial fibrillation patients were divided into two groups (treatment and control groups). The echocardiography parameters, including LA active emptying volume (LAAEV), LA active emptying fraction.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.10.5
- DOI:
- 10.4238/2013.September.10.5
Odorant receptor genes are expressed in olfactory neuroblastoma
Authors: D.C. Gonzalez-Kristeller, L.M. Gutiyama, A.H. Campos, F.A. Soares, H. Brentani and B. Malnic
Olfactory neuroblastoma (ONB) is a malignant tumor found in the human nasal cavity. These tumors are rare and poorly characterized at the molecular level. In this study, we asked whether olfactory-specific genes are expressed in ONBs by using reverse-transcriptase-polymerase chain reaction. We found that the olfactory marker protein and the RIC-8B genes, .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.10.4
- DOI:
- 10.4238/2013.September.10.4
Fourteen years after the Shahid-Rajaei dam construction: an evaluation of morphometric and genetic differentiation between isolated up- and downstream populations of Capoeta capoeta gracilis (Pisces: Cyprinidae) in the Tajan River of Iran
Authors: Hossein AnvariFar, H. Farahmand, D.M. Silva, R.P. Bastos, A. Khyabani and Hassan AnvariFar
We evaluated the effects of the Shahid-Rajaei dam, 14 years after its construction, on morphometric and genetic divergence between up- and downstream populations of the Iranian fish Siah-Mahi (Capoeta capoeta gracilis). Sixty-six specimens were analyzed. There were significant differences between the 2 groups in the means of 16 morphometric characters (un.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.10.3
- DOI:
- 10.4238/2013.September.10.3
Genetic variability in Melipona scutellaris from Rec�´ncavo, Bahia, Brazil
Authors: J.L. Viana, A.K. Francisco, C.A.L. Carvalho and A.M. Waldschmidt
Bees play a key role in pollination and thereby help maintain plant diversity. The stingless bee Melipona scutellaris is an important pollinator in northeastern Brazil because it is endemic to this region. Both deforestation and timber harvesting have reduced the nesting sites for this species, thus reducing its population and range. Genetic studies may h.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.10.1
- DOI:
- 10.4238/2013.September.10.1
Genetic diversity of gabiroba based on random amplified polymorphic DNA markers and morphological characteristics
Authors: E.S. de Assis, E.F. dos Reis, J.F.N. Pinto, L.A.S. Contim and L.A.S. Dias
The fragmentation of the original vegetation of the Cerrado biome, caused by the expansion of agricultural areas, mainly in central-west Brazil, calls for an assessment of the native population of this vegetation, especially of the species of interest for domestication and sustainable use. The purpose of this study was to characterize the genetic diversit.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.11.7
- DOI:
- 10.4238/2013.March.11.7