Cytogenomics
Identification of naturalized goat breeds under conservation from northeastern Brazil using chromosomal markers
Authors: R.P. Santos, P.R.A.M. Affonso, D. Diniz, A.S. Medrado, K.M. Silva and P.L.S. Carneiro
In order to provide the first cytogenetic data of naturalized and threatened goat breeds from northeastern Brazil, cytogenetic analyses were carried out in individuals of Repartida and Moxotó breeds raised in Bahia and Ceará States. Males and females of both breeds had 2n = 60, with 29 autosomal acrocentric pairs plus the sex chromosome pair.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.29.3
- DOI:
- 10.4238/2013.August.29.3
Detection and expression of bovine papillomavirus in blood of healthy and papillomatosis-affected cattle
Authors: M.A.R. Silva, B.M.F. De Albuquerque, N.E. Pontes, L.C.A. Coutinho, M.C.G. Leit�£o, M.C. Reis, R.S. Castro and A.C. Freitas
Papillomaviruses (PV) are double-stranded DNA viruses that can cause benignant and malignant tumors in amniotes. There are 13 types of bovine papillomavirus (BPV-1 to -13); they have been found in reproductive tissues and body fluids. Normally these viruses are detected in epithelial tissue. We looked for BPV in the blood of healthy cattle and cattle with.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.31
- DOI:
- 10.4238/2013.February.28.31
Loop-tail phenotype in heterozygous mice and neural tube defects in homozygous mice result from a nonsense mutation in the Vangl2 gene
Authors: B. Chen, H.H. Mao, L. Chen, F.L. Zhang, K. Li and Z.F. Xue
N-ethyl-N-nitrosourea (ENU) is a powerful point mutagen that can generate random mutations. It has been used to generate mouse mutations to produce phenotypic models of human disease. Neural tube defects (NTD) are common birth defects in which the brain and/or spinal cord can be exposed; however, the mechanisms of these defects are poorly understood. Cran.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.22.2
- DOI:
- 10.4238/2013.January.22.2
Genetic diversity of Palestine landraces of faba bean (Vicia faba) based on RAPD markers
Authors: R. Basheer-Salimia, M. Shtaya, M. Awad, J. Abdallah and Y. Hamdan
Until now, neither phenotypic nor molecular approaches have been used to characterize the landraces of Palestine faba beans (Vicia faba). We used PCR-based RAPD markers to determine the genetic diversity and relatedness among 26 Palestinian faba bean landraces (traditional farmers’ varieties) from 8 localities in the West Bank, Palestine. In tests w.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.8
- DOI:
- 10.4238/2013.September.3.8
Cloning and molecular characterization of a cDNA encoding a small GTPase from Hevea brasiliensis
Authors: H.L. Li, D. Guo, W.M. Tian and S.Q. Peng
Small GTPases play a critical role in the regulation of a range of cellular processes including growth, differentiation, and intracellular transportation. The cDNA encoding a small GTPase, designated as HbGTPase1, was isolated from Hevea brasiliensis. HbGTPase1 was 882 bp long containing a 612-bp open reading frame encoding a putative protein of 203 amino.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.7
- DOI:
- 10.4238/2013.September.3.7
Association between single nucleotide polymorphisms of the osteoprotegerin gene and postmenopausal osteoporosis in Chinese women
Authors: J.F. Song, Z.Z. Jing, W. Hu and Y.X. Su
Osteoporosis is an important and common complex health problem, particularly in postmenopausal women. It is characterized by a reduction in bone mineral density (BMD) and a deterioration of bone microarchitecture with a consequent increase of fracture risk. The osteoprotegerin (OPG) gene is considered to play an important role in the pathogenesis of osteo.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.4
- DOI:
- 10.4238/2013.September.3.4
Transcriptome network-based method to identify genes associated with unruptured intracranial aneurysms
Authors: L. Wei, Y.J. Gao, S.P. Wei, Y.F. Zhang, W.F. Zhang, J.X. Jiang, Z.Y. Sun and W. Xu
Intracranial aneurysm is a balloon or sac-like dilatation of blood vessels inside the brain. Despite their importance, the biological mechanisms of intracranial aneurysms are not totally understood. We used public genome-wide gene expression profile data to identify potential genes that are involved in intracranial aneurysm in order to construct a regulat.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.2
- DOI:
- 10.4238/2013.September.3.2
Positional effects of polymorphisms in probe-target sequences on genoplot images of oligonucleotide microarrays
Authors: T.L. Cui, H. Nakaoka, K. Akiyama, H. Kamura, K. Hosomichi, J. Bae, H. Cheong, H. Shin, T. Yada and I. Inoue
Single nucleotide polymorphisms (SNPs) present in probetarget sequences (SPTS) have been shown to be associated with abnormal genoplot images. We explored the effects of SPTS positions on genoplot images using a data set from a genome-wide association study typed on an Illumina Human Hap300 platform. We screened the physical g.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr737
- DOI:
- 10.4238/vol9-1gmr737
Genetic relationships between Lolium (Poaceae) species revealed by RAPD markers
Authors: X. Ma, X.-Y. Gu, T.-T. Chen, S.-Y. Chen, L.-K. Huang and X.-Q. Zhang
The genus Lolium is one of the most important groupings of temperate forage grasses, including about eight recognized species that are native to some temperate and subtropical regions of the northern hemisphere. We examined genetic relationships among 18 accessions representing all Lolium species using RAPD markers. Among 50 random primers that we screene.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.11.4
- DOI:
- 10.4238/2013.March.11.4
Comparative analysis of myostatin gene and promoter sequences of Qinchuan and Red Angus cattle
Authors: Y.L. He, Y.H. Wu, F.S. Quan, Y.G. Liu and Y. Zhang
To better understand the function of the myostatin gene and its promoter region in bovine, we amplified and sequenced the myostatin gene and promoter from the blood of Qinchuan and Red Angus cattle by using polymerase chain reaction. The sequences of Qinchuan and Red Angus cattle were compared with those of other cattle breeds available in GenBank. Exon s.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.6
- DOI:
- 10.4238/2013.September.4.6