Cytogenomics
Construction of suppressor of cytokine signaling 2 (SOCS2) adenoviral overexpression vector and its impact on growth hormone- induced lipolysis in swine primary adipocytes
Authors: H.L. Yang, J. Yan, M. Feng, X. Tan, G.Y. Yan, L. Gan and C. Sun
We investigated the effect of overexpression suppressor of cytokine signaling 2 (SOCS2) on lipolysis in swine primary adipocytes (pAd) induced by growth hormone (GH). We constructed pAd-SOCS2 adenoviral overexpression vectors to infect HEK293 cells for virus packaging and propagation. Cultured swine primary adipocytes were infected with virus particles; a.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.9.2
- DOI:
- 10.4238/2013.January.9.2
A proposed model for the flowering signaling pathway of sugarcane under photoperiodic control
Authors: C.P. Coelho, A.P. Costa Netto, J. Colasanti and A. Chalfun-Junior
Molecular analysis of floral induction in Arabidopsis has identified several flowering time genes related to 4 response networks defined by the autonomous, gibberellin, photoperiod, and vernalization pathways. Although grass flowering processes include ancestral functions shared by both mono- and dicots, they have developed their own mechanisms to transmi.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.6
- DOI:
- 10.4238/2013.April.25.6
Evaluation of genetic diversity in fig accessions by using microsatellite markers
Authors: A.D.B. do Val, C.S. Souza, E.A. Ferreira, S.M.L. Salgado, M. Pasqual and G.M.A. Can�?§ado
Fig (Ficus carica L.) is a fruit of great importance worldwide. Its propagation is carried out with stem cuttings, a procedure that favors the occurrence of synonymy among specimens. Thus, molecular markers have become an important tool for studies of DNA fingerprinting, germplasm characterization, and genetic diversity evaluation in this plant species. T.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.9
- DOI:
- 10.4238/2013.April.25.9
CTLA-4 and CD86 genetic variants and haplotypes in patients with rheumatoid arthritis in southeastern China
Authors: C.-P. Liu, J.-A. Jiang, T. Wang, X.-M. Liu, L. Gao, R.-R. Zhu, Y. Shen, M. Wu, T. Xu and X.-G. Zhang
The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and costimulatory molecule (CD80/CD86) genes are important susceptibility genes associated with autoimmune diseases. CTLA-4 polymorphisms have been found to be associated with various autoimmune diseases. However, the association data are inconsistent for rheumatoid arthritis (RA). We investigated t.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.8
- DOI:
- 10.4238/2013.April.25.8
Genetic characterization of Fusarium graminearum and F. culmorum isolates from Turkey by using random-amplified polymorphic DNA
Authors: E. Y�?¶r�?¼k and G. Albayrak
Five Fusarium graminearum and 12 F. culmorum isolates, primarily pathogenic species of Fusarium head blight, were obtained from naturally infected wheat from various agro-ecological regions of Turkey. Genotyping of the isolates was carried out using random-amplified polymorphic DNA (RAPD). Sixty-five 10-mer oligonucleotide primers were used to amplify the.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.7
- DOI:
- 10.4238/2013.April.25.7
Karyotype characterization reveals active 45S rDNA sites located on chromosome termini in Smilax rufescens (Smilacaceae)
Authors: D. Pizzaia, V.M. Oliveira, A.R. Martins, B. Appezzato-da-Gl�?³ria, E. Forni-Martins and M.L.R. Aguiar-Perecin
The genus Smilax (Smilacaceae) includes species of medicinal interest; consequently, their identification is important for the control of raw material used in the manufacture of phytotherapeutic products. We investigated the karyotype of Smilax rufescens in order to look for patterns that would be useful for comparative studies of this genus. To accomplis.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.1
- DOI:
- 10.4238/2013.April.25.1
ATP-dependent chromatin remodeling and histone acetyltransferases in 5-FU cytotoxicity in Saccharomyces cerevisiae
Authors: R. Matuo, F.G. Sousa, D. Bonatto, A.A. Mielniczki-Pereira, J. Saffi, D.G. Soares, A.E. Escargueil, A.K. Larsen and J.A.P. Henriques
Chromatin is thought to modulate access of repair proteins to DNA lesions, and may be altered by chromatin remodelers to facilitate repair. We investigated the participation of chromatin remodelers and DNA repair in 5-fluorouracil (5-FU) cytotoxicity in Saccharomyces cerevisiae. 5-FU is an antineoplastic drug commonly used in clinical settings. Among the .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.26.6
- DOI:
- 10.4238/2013.April.26.6
Serotonin receptor 2C gene polymorphism associated with post-stroke depression in Chinese patients
Authors: W.K. Tang, N. Tang, C.D. Liao, H.J. Liang, V.C.T. Mok, G.S. Ungvari and K.S. Wong
The serotonin receptor 2C (HTR2C) gene has been shown to play a pivotal role in major depression. We examined the association between post-stroke depression (PSD) and polymorphism in HTR2C. A cohort of 223 patients with acute lacunar stroke admitted to the stroke unit of a university-affiliated regional hospital in Hong Kong was recruited. Three months af.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.8
- DOI:
- 10.4238/2013.May.13.8
A phytotoxin Solanapyrone-A downregulates calcium-dependent protein kinase activity in potato
Authors: A. Hassan, N. Hatsugai and M.M. Shah
We previously demonstrated that alternaric acid, a host-specific toxin produced by the plant pathogenic fungus Alternaria solani, in the presence of Ca2+ and Mg2+, stimulated in vitro phosphorylation of His-tagged calcium-dependent protein kinase 2 from potato cultivar Rishiri (RiCDPK2). Herein, we report that Solanapyrone-A (SpA), a non-host-specific tox.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.7
- DOI:
- 10.4238/2013.May.13.7
Descriptor selection for banana accessions based on univariate and multivariate analysis
Authors: L.P. Brand�?£o, C.P.F. Souza, V.M. Pereira, S.O. Silva, J.A. Santos-Serejo, C.A.S. Ledo and E.P. Amorim
Our objective was to establish a minimum number of morphological descriptors for the characterization of banana germplasm and evaluate the efficiency of removal of redundant characters, based on univariate and multivariate statistical analyses. Phenotypic characterization was made of 77 accessions from Bahia, Brazil, using 92 descriptors. The selection of.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.14.1
- DOI:
- 10.4238/2013.May.14.1