Bioinformatics
Cloning, identification, and bioinformatics analysis of a putative aquaporin TsAQP from Trichinella spiralis
Authors: J.M. Cui, N.Z. Zhang, W.H. Li, H.B. Yan and B.Q. Fu
Vaccination as a preventative strategy against Trichinella spiralis infection is an ongoing effort, although no ideal vaccine candidates have been identified until now. Identification of more effective antigens that have a role in essential life stages of the parasite and that may be effective vaccine candidates is therefore o.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.14
- DOI:
- 10.4238/2015.October.19.14
Characterization of novel microsatellite markers derived from Korean rose bitterling (Rhodeus uyekii) genomic library
Authors: W.J. Kim1, E.H. Shin1, H.J. Kong1, H.S. Kim1, B.S. Kim1, B.H. Nam1, Y.O. Kim1, C.H. Kim2, H. Jung1 and C.M. An1
Korean rose bitterling (Rhodeus uyekii) is a freshwater fish endemic to Korea. Natural populations of this species have experienced severe declines as a result of habitat fragmentation and water pollution. To conserve and restore R. uyekii, the genetic diversity of this species needs to be assessed at the population level. Eighteen novel polymorphic micro.. Read More»
- Genet. Mol. Res. 13(4):
Genetic diversity and differentiation of the endangered and endemic species Sauvagesia rhodoleuca in China as detected by ISSR analysis
Authors: S.F. Chai1,2, Y.S. Jiang2, X.Y. Zhuang1, Y.C. Shi2, X. Wei2, W.H. Luo2 and Z.Y. Chen2
Sauvagesia rhodoleuca (Ochnaceae) is an endangered plant that is endemic to southern China. The levels of genetic variation and patterns of population structure in S. rhodoleuca were investigated using inter-simple sequence repeat markers. Eleven primers were used to amplify DNA samples from 117 individuals, and a total of 92 loci were detected. Our resul.. Read More»
- Genet. Mol. Res. 13(4):
Study of polymorphic variants of the serotonin 2A receptor gene (5-HT2A) and its possible effects on smoking habits of a population from northeastern Brazil
Authors: E.S. Ramos Neto1,2, J.O. M�¡gulas1,2, J.J.S. Sousa 1, A.C.M. Moura1, G.R. Pinto1,2, F.K.N. Yoshioka1,2, R. Canalle1,2 and F.J.N. Motta1,2
Previous studies have revealed a genetic component, including genetic polymorphisms in the serotonergic pathway, particularly in the serotonin receptor gene (5-HT2A). The aim of this study was to investigate associations of the T102C (rs6313) and A-1438G (rs6311) polymorphisms with tobacco use in a population from northeastern Brazil. We evaluated these p.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.3
- DOI:
- 10.4238/2014.October.20.3
Elevated TrkA receptor expression is associated with all-trans retinoic acid-induced neuroblastoma differentiation
Authors: Q. Gao, C.F. Chen, Q. Dong, L. Hou, X. Chen, Y.L. Zhi, X. Li, H.T. Lu and H.Y. Zhang
Neuroblastoma is the most common and one of the deadliest among pediatric tumors; however, a subset of infants with neuroblastoma display spontaneous regression. The mechanism of spontaneous regression remains to be elucidated. TrkA plays an essential role in the differentiation and functionality of neurons; abundant TrkA expression is associated with fav.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.15
- DOI:
- 10.4238/2015.October.26.15
Bioinformatics: an overview and its applications
Authors: W.J.S. Diniz and F. Canduri
Technological advancements in recent years have promoted a marked progress in understanding the genetic basis of phenotypes. In line with these advances, genomics has changed the paradigm of biological questions in full genome-wide scale (genome-wide), revealing an explosion of data and opening up many possibilities. On the ot.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019645
- DOI:
- 10.4238/gmr16019645
First isolation and characterization of genomic SSR markers for the giant red shrimp Aristaeomorpha foliacea (Risso, 1827)
Authors: R. Cannas S. Marcias F. Sacco A. Cau A.M. Deiana
Fourteen microsatellite markers were isolated from the giant red shrimp Aristaeomorpha foliacea (Risso, 1827) using the FIASCO protocol (fast isolation by AFLP of sequences containing repeats). Polymorphism was assessed in 30 individuals from two localities of the western Mediterranean basin (N = 20 from Sardinia and N = 10 from Sicily); nine loci showed .. Read More»
- Genet. Mol. Res. 3(4):
- 2012.August.17.1
- DOI:
- 10.4238/2012.August.17.1
Genotyping of urinary samples stored with EDTA for forensic applications
Authors: S.H. Zhang S.M. Zhao Z.M. Zhao C.T. Li
Individual identification of urinary samples is necessary when sample switching or handling are suspected during a judicial process. To improve the rate of successful genotyping of urinary samples, we examined the stability of DNA in urinary samples stored for up to 30 days. Urinary samples from 20 healthy individuals (10 males and 10 females) were stored.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.10.5
- DOI:
- 10.4238/2012.May.10.5
A novel strategy for identification of 47 pomegranate (Punica granatum) cultivars using RAPD markers
Authors: Y.P. Zhang H.H. Tan S.Y. Cao X.C. Wang G. Yang J.G. Fang
DNA marker can be used for precise plant cultivar identification. However, DNA markers have often not been used effectively for the identification of plant cultivars due to a lack of an effective analysis strategy. We used a novel strategy for effective identification of plant individuals based on a new way of recording DNA fingerprints of the genotyped plan.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.30.1
- DOI:
- 10.4238/2012.May.30.1
Genetic relationships among five varieties of Curcuma alismatifolia (Zingiberaceae) based on ISSR markers
Authors: S. Taheri T.L. Abdullah N.A.P. Abdullah Z. Ahmad
The genus Curcuma is a member of the ginger family (Zingiberaceae) that has recently become popular for use as flowering pot plants, both indoors and as patio and landscape plants. We used PCR-based molecular markers (ISSRs) to assess genetic variation and relationships between five varieties of curcuma (Curcuma alismatifolia) cultivated in Malaysia. Sixteen.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.31.4
- DOI:
- 10.4238/2012.August.31.4