Bioinformatics
Bayesian network structure learning based on the chaotic particle swarm optimization algorithm
Authors: Q. Zhang, Z. Li, C.J. Zhou and X.P. Wei
The Bayesian network (BN) is a knowledge representation form, which has been proven to be valuable in the gene regulatory network reconstruction because of its capability of capturing causal relationships between genes. Learning BN structures from a database is a nondeterministic polynomial time (NP)-hard problem that remains one of the most exciting chal.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.12
- DOI:
- 10.4238/2013.October.10.12
Phylogenetic analysis of substrate-binding subunits in an osmoprotectant system
Authors: T.J.D. Coutinho, N.F. Rodrigues and S.T. Farias
Substrate-binding subunits are important components of the solute importation system, known as the osmoprotectant system, which consists of a membrane protein belonging to the ABC superfamily... Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.1
- DOI:
- 10.4238/2013.November.22.1
FastJoin, an improved neighbor-joining algorithm
Authors: J. Wang, M.-Z. Guo and L.L. Xing
Reconstructing the evolutionary history of a set of species is an elementary problem in biology, and methods for solving this problem are evaluated based on two characteristics: accuracy and efficiency. Neighbor-joining reconstructs phylogenetic trees by iteratively picking a pair of nodes to merge as a new node until only one.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.19.10
- DOI:
- 10.4238/2012.July.19.10
DNA barcoding based on plastid matK and RNA polymerase for assessing the genetic identity of date (Phoenix dactylifera L.) cultivars
Authors: M.R. Enan and A. Ahmed
The cultivated date palm is the most agriculturally important species of the Arecaceae family. The standard chloroplast DNA barcode for land plants recommended by the Consortium for the Barcode of Life plant working group needs to be evaluated for a wide range of plant species. Therefore, we assessed the potential of the matK .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.February.14.2
- DOI:
- 10.4238/2014.February.14.2
Alteration of Phascolosoma esculenta heat shock protein 90 expression under heavy metal exposure and thermal stress
Authors: C.H. Li, X.R. Su, M.Q. Wang, Y.Y. Li, Y. Li, J. Zhou and T.W. Li
The full-length complementary DNA (cDNA) of heat shock protein 90 was cloned from Phascolosoma esculenta (PeHSP90) using expressed sequence tag and rapid amplification of cDNA end approaches. The cDNA of PeHSP90 was 2521 bp including a 5'-untranslated region of 110 bp, a 3'-untranslated region of 230 bp, and an open reading frame of 2181 bp. All of the ch.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.14
- DOI:
- 10.4238/2012.July.10.14
Genetic diversity and population structure of Chinese pony breeds using microsatellite markers
Authors: L.X. Xu, S.L. Yang, R.Y. Lin, H.B. Yang, A.P. Li and Q.S. Wan
China is one of the principal origins of ponies in the world. We made a comprehensive analysis of genetic diversity and population structure of Chinese ponies based on 174 animals of five indigenous Chinese pony breeds from five provinces using 13 microsatellite markers. One hundred and forty-four alleles were detected; the mean number of effective allele.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.25.4
- DOI:
- 10.4238/2012.June.25.4
Effects of lipopolysaccharide on the stearoyl-coenzyme A desaturase mRNA level in bovine primary hepatic cells
Authors: Q.D. Jiang, H.P. Li, F.J. Liu, X.J. Wang, Y.J. Guo, L.F. Wang, W.F. Lu, H.J. Li, X.P. Li and Y.Y. Wang
This study aimed to compare the effects of lipopolysaccharide (LPS) on stearoyl-coenzyme A desaturase (SCD) gene expression in mouse primary hepatic cells. To obtain sufficient total RNA, primary hepatic cells were plated on 6-cm diameter-type collagen 1-coated dishes (1 x 106 cells per dish). The test was divided into 6 group.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.12
- DOI:
- 10.4238/2014.January.24.12
Urinary nerve growth factor levels could be a biomarker for overactive bladder symptom: a meta-analysis
Authors: H.C. Qu, S. Yan, X.L. Zhang, X.W. Zhu, Y.L. Liu and P. Wang
To examine whether urinary tract nerve growth factor (uNGF) could be a biomarker for overactive bladder (OAB) symptom, we conducted a comprehensive meta-analysis of 8 case-control studies. In all the studies considered, patients with OAB symptom had a higher uNGF level compared to healthy people. In addition, patients had a significantly lower uNGF level .. Read More»
- Genet. Mol. Res. 13(4):
Monocyte/macrophage �²2-AR as a target of antisympathetic excitation-induced atherosclerotic progression
Authors: Y.L. Guo, J.Q. Zhou, C.Q. Xiang, W.H. Yang, B. Zhang, W.J. Dai, J.H. Liu and S.J. Zheng
The aim of this study was to determine whether monocyte/macrophage β2-AR could act as the therapeutic target of antisympathetic excitation-induced atherosclerotic progression. Cultivated human THP-1 cells were divided into different groups and incubated with isoprenaline, metoprolol, propranolol or β2-AR blocker for 24 h, together with oxidized .. Read More»
- Genet. Mol. Res. 13(4):
Is there a cryptic species of the golden snapper (Lutjanus johnii)?
Authors: A.B. Adibah and M.N. Darlina
For centuries, morphology-based fish identification has been applied without molecular evaluation. Many studies showed that specimens with a similar morphology are frequently found to be quite genetically distinct. One of the fish species that still remains taxonomically problematic is a commercial snapper species, Lutjanus johnii. Because of morphologica.. Read More»
- Genet. Mol. Res. 13(4):