Bioinformatics
Identification of long non-coding RNA involved in osteogenic differentiation from mesenchymal stem cells using RNA-Seq data
Authors: W.Q. Song, W.Q. Gu, Y.B. Qian, X. Ma, Y.J. Mao and W.J. Liu
The aim of this study was to identify long non-coding RNA (lncRNA) associated with osteogenic differentiation from mesenchymal stem cells (MSCs) using high-throughput RNA sequencing (RNA-Seq) data. RNA-Seq dataset was obtained from the European Bioinformatics Institute (accession No. PRJEB4496), including two replicates each for immortalized mesenchymal s.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.14
- DOI:
- 10.4238/2015.December.23.14
Comparative proteomic analysis reveals mite (Varroa destructor) resistance-related proteins in Eastern honeybees (Apis cerana)
Authors: T. Ji, F. Shen, Z. Liu, L. Yin, J. Shen, Q. Liang and Y.X. Luo
The mite (Varroa destructor) has become the greatest threat to apiculture worldwide. As the original host of the mite, Apis cerana can effectively resist the mite. An increased understanding of the resistance mechanisms of Eastern honeybees against V. destructor may help researchers to protect other species against these parasites. In this study, the prot.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.21.18
- DOI:
- 10.4238/2015.August.21.18
A wavelet-based feature vector model for DNA clustering
Authors: J.P. Bao and R.Y. Yuan
DNA data are important in the bioinformatic domain. To extract useful information from the enormous collection of DNA sequences, DNA clustering is often adopted to efficiently deal with DNA data. The alignment-free method is a very popular way of creating feature vectors from DNA sequences, which are then used to compare DNA similarities. This paper propo.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.26
- DOI:
- 10.4238/2015.December.29.26
Isolation and characterization of polymorphic EST-SSR and genomic SSR markers in spotted mandarin fish (Siniperca scherzeri Steindachne)
Authors: Y.Q. Dou, X.F. Liang, M. Yang, C.X. Tian, S. He and W.J. Guo
Spotted mandarin fish (Siniperca scherzeri Steindachne) feed solely on live fry of other fish species once the fry start feeding in the wild. In the present study, 26 polymorphic transcriptome-derived simple sequence repeat (SSR) markers and 14 genomic SSR markers were developed and characterized in S. scherzeri Steindachne by combining a biotin-enrichmen.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.41
- DOI:
- 10.4238/2015.December.29.41
Association between the AGTR1 A1166C polymorphism and risk of IgA nephropathy: a meta-analysis
Authors: J.M. Xu, X. Song, F. Gao and R. Wang
Numerous studies have evaluated the association between the A1166C polymorphism in the angiotensin II type 1 receptor (AGTR1) gene and immunoglobulin A nephropathy (IgAN) risk. However, this relationship remains controversial. Our aim was to evaluate the relationship between this polymorphism and IgAN susceptibility by performing a meta-analysis. Articles.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.47
- DOI:
- 10.4238/2015.December.29.47
Public sphere and the sustainability of the bioinformatics promise
Authors: Marcelo Leite
The literature about genomics and bioinformatics achievements in high-impact journals such as Nature and Science has raised disproportionate expectations amongst the general public about fast and revolutionary drugs and breakthroughs in biomedicine. However, the yield obtained by database mining activities has been modest, as .. Read More»
- Genet. Mol. Res. 3(4):
Bioinformatics: perspectives for the future
Authors: Luciano da Fontoura Costa
I give here a very personal perspective of Bioinformatics and its future, starting by discussing the origin of the term (and area) of bioinformatics and proceeding by trying to foresee the development of related issues, including pattern recognition/data mining, the need to reintegrate biology, the potential of complex network.. Read More»
- Genet. Mol. Res. 3(4):
Section for the International Conference on Bioinformatics and Computational Biology
Authors: Jos�© Miguel Ortega
-.. Read More»
- Genet. Mol. Res. 3(4):
Professor Clibas Vieira 1927 - 2004
Authors: N.M.A. Nassar
-.. Read More»
- Genet. Mol. Res. 3(3):
A new set of bioinformatics tools for genome projects
Authors: Luiz G.P. Almeida, Roger Paix�£o, Rangel C. Souza, Gisele C. da Costa, Darcy F. de Almeida, Ana T.R. de Vasconcelos
A new tool called System for Automated Bacterial Integrated Annotation - SABIA (SABIÁ being a very well-known bird in Brazil) was developed for the assembly and annotation of bacterial genomes. This system performs automatic tasks of assembly analysis, ORFs identification/analysis, and extragenic region analyses. Genome.. Read More»
- Genet. Mol. Res. 3(1):