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Relationship between serum creatinine and obesity in children in Xinjiang, China
Authors: X.-M. Li, Y.-T. Ma, X. Xie, Y.-N. Yang, X.-M. Li and Y.-Y. Zheng
This study was designed to analyze the relationship between serum creatinine and body mass index in children in Xinjiang, China. We used a stratified sampling method to select 5222 children aged 6-17 years in 3 areas in Xinjiang and then measured serum creatinine with an enzymatic method. Our analysis showed that the mean seru.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.13
- DOI:
- 10.4238/2014.April.3.13
In vitro effects of Ala16Val manganese superoxide dismutase gene polymorphism on human white blood cells exposed to methylmercury
Authors: T.D. Algarve1, F. Barbisan2, E.E. Ribeiro3, M.M.M.F. Duarte4, M.F. M�¢nica-Cattani1, C.P. Mostardeiro2, A.F. Lenz1 and I.B.M. da Cruz1,2,4
Environmental contamination by methylmercury (MeHg) is an enormous public health problem in world regions such as Amazonia. MeHg toxic effects seem to be influenced by environmental and genetic factors. However, few studies have evaluated the genetic influences of MeHg toxicity in humans. Therefore, the aim of this study was to evaluate the genetic influe.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.7
- DOI:
- 10.4238/2013.October.29.7
Entoepidemiology of Chagas disease in northwest S�£o Paulo and cytogenetic analysis of its main vector, Triatoma sordida (Hemiptera: Triatominae)
Authors: R. Silistino-Souza1, K.C.C. Alevi1, N.F.C. Castro1, M.N. Freitas1, M.D. Papa2, S.A.S. Scandar2, R.R. Bestetti3, J.A. Rosa4 and M.T.V. Azeredo-Oliveira
One century after the discovery of Chagas disease, it is still considered as a major health problem, causing more deaths in the Americas than any other parasitic disease. The northwest region of São Paulo, a macro-region that includes cities with a high-quality of life, has particularly high rates of Chagas disease... Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.8
- DOI:
- 10.4238/2013.November.22.8
Polymorphism of SREBP1 is associated with beef fatty acid composition in Simmental bulls
Authors: L. Xu*, L.P. Zhang*, Z.R. Yuan, L.P. Guo, M. Zhu, X. Gao, H.J. Gao, J.Y. Li and S.Z. Xu
The sterol regulatory element binding factor 1 gene (SREBP1) plays an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. The objective of this study was to investigate the effect of genetic polymorphisms of SREBP1 on the fatty acid composition of muscle and carcass traits in Simmental bulls and Snow Dragon black ca.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.7
- DOI:
- 10.4238/2013.November.22.7
Further evidence for the contribution of the BRCA1-interacting protein-terminal helicase 1 (BRIP1) gene in breast cancer susceptibility
Authors: L.P. Ren, Y.S. Xian, D.M. Diao, Y. Chen, Q. Guo and C.X. Dang
BRCA1-interacting protein C-terminal helicase 1 (BRIP1) is a DNA helicase that influences the DNA repair ability and tumor suppressor function of BRCA1. Truncating BRIP1 mutations have been described as cancer susceptibility alleles. To evaluate BRIP1 polymorphisms as risk factors for breast cancer, we performed a detailed analysis of possible single nucl.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.6
- DOI:
- 10.4238/2013.November.22.6
New insights into the prolactin-RsaI (PRL-RsaI) locus in Chinese Holstein cows and its effect on milk performance traits
Authors: C.H. Dong1, X.M. Song2, L. Zhang2, J.F. Jiang2, J.P. Zhou1 and Y.Q. Jiang2
Prolactin (PRL) plays central roles in mammals’ reproduction, gland development, milk secretion, and the expression of milk protein genes. In dairy cattle, the PRL gene is a potential quantitative trait locus and genetic marker related to milk performance traits. Here, a total of 586 randomly selected Chinese Holstein cows were genotyped for locus P.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.3
- DOI:
- 10.4238/2013.November.22.3
Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts
Authors: Y. Hu, X.-X. Tang and H.-Y. He
The aim of this study was to observe the dynamic expression of osteopontin, type I collagen, and osteocalcin genes during the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts and confirm whether BMSCs can differentiate and mature into osteoblasts. A healthy, 2-month-old Altay tailed sheep was obtained, and 10 mL bone marrow was .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.4
- DOI:
- 10.4238/2013.December.11.4
A new tetra-primer ARMS-PCR for genotyping bovine kappa-casein polymorphisms
Authors: P.A.S. Fonseca, I.C. Rosse, M. DeMiranda, M.A. Machado,R.S. Verneque, M.G.C.D. Peixoto and M.R.S. Carvalho
Kappa-casein (κ-casein) is one of the most abundant milk proteins. Its main function is to avoid the aggregation of casein micelles, keeping them, and therefore calcium phosphate, in pockets in solution. In bovines, a κ-casein functional polymorphism has been associated with fat, calcium, and protein milk contents and faster curd contraction i.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.3
- DOI:
- 10.4238/2013.December.11.3
Random regression models using Legendre orthogonal polynomials to evaluate the milk production of Alpine goats
Authors: F.G. Silva, R.A. Torres, L.F. Brito, R.F. Euclydes, A.L.P. Melo,N.O. Souza1, J.I. Ribeiro Jr. and M.T. Rodrigues
The objective of this study was to identify the best random regression model using Legendre orthogonal polynomials to evaluate Alpine goats genetically and to estimate the parameters for test day milk yield. On the test day, we analyzed 20,710 records of milk yield of 667 goats from the Goat Sector of the Universidade Federal de Viçosa. The evaluat.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.11.1
- DOI:
- 10.4238/2013.December.11.1
Differences in frequencies of UGT1A9, 1A7, and 1A1 genetic polymorphisms in Chinese Tibetan versus Han Chinese populations
Authors: W. Yan, Y.W. Wang, F.F. Yang, M. Wang, X.Q. Zhang, J. Dong,E. Chen and J. Yang
As part of a series of pharmacogenomics studies of the Chinese population, we investigated genetic polymorphisms of some UGT1A regions. The three genes that were analyzed were UGT1A9, 1A7, and 1A1; we sequenced their exons, together with promoters, surrounding introns and 3'-untranslated regions (3êÂ?Â?UTR) in 100 unrelated-healthy Chinese Tibetan individua.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.10.6
- DOI:
- 10.4238/2013.December.10.6