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Animal Genetics   Research Article

Evaluation of TFAM and FABP4 gene polymorphisms in three lines of Nellore cattle selected for growth

Authors: D.R. Ayres, F.R.P. Souza, M.E.Z. Mercadante, L.F.S. Fonseca, H. Tonhati, J.N.S.G. Cyrillo, S.F.M. Bonilha and L.G. Albuquerque

We analyzed the polymorphisms TFAM HaeIII, TFAM MboI and FABP4 MspA1I in three Nellore lines selected for growth in order to evaluate how selection affects the frequencies of these polymorphisms and evaluate their association with growth and carcass traits in Zebu cattle. Birth, weaning and yearling weights, rump height, longi.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr850
DOI:
10.4238/vol9-4gmr850
Medical Genetics   Research Article

An interspecific QTL study of Drosophila wing size and shape variation to investigate the genetic basis of morphological differences

Authors: B.P. Matta and B.C. Bitner-Math�©

The Drosophila wing has been used as a model in studies of morphogenesis and evolution; the use of such models can contribute to our understanding of mechanisms that promote morphological divergence among populations and species. We mapped quantitative trait loci (QTL) affecting wing size and shape traits using highly inbred i.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr929
DOI:
10.4238/vol9-4gmr929
Medical Genetics   Research Article

Analysis of glutathione peroxidase 1 gene polymorphism and Keshan disease in Heilongjiang Province, China

Authors: H.L. Wei, J.R. Pei, C.X. Jiang, L.W. Zhou, T. Lan, M. Liu and T. Wang

Keshan disease (KD) is an endemic cardiomyopathy associated with selenium deficiency. Recent studies indicate that glutathione peroxidase 1 (GPx1) mutation decreases GPx activity in myocardial cells and increases the risk of KD. To further clarify the correlation between GPx1 polymorphism and KD, we analyzed GPx1 polymorphism,.. Read More»

Genet. Mol. Res. 10(4):
Animal Genetics   Research Article

Molecular sexing of unusually large numbers of Spheniscus magellanicus (Spheniscidae) washed ashore along the Brazilian coast in 2008

Authors: E.C. Reis, R.M. Aires, J.F. Moura, C.A.R. Matias, M. Tavares, P.H. Ott, S. Siciliano and G. L�´bo-Hajdu

There have been few studies on Magellanic penguins (Spheniscus magellanicus). In 2008, these penguins washed ashore along the Brazilian coast in unusually high numbers, some reaching as far as northeast Brazil. As Magellanic penguins show little sexual dimorphism, sex determination by morphological features is not accurate. He.. Read More»

Genet. Mol. Res. 10(4):
Plant Genetics   Research Article

Isolation of fertility-related genes of multiple-allele-inherited male sterility in Brassica rapa ssp pekinensis by cDNA-AFLP

Authors: R.Q. Ji, Q. Song, X.F. Xin, X. Zhou and H. Feng

To better understand the molecular mechanisms of multiple-allele-inherited male sterility in Chinese cabbage (Brassica rapa ssp pekinensis), differentially expressed genes in fertile and sterile plants must be isolated. We used cDNA-AFLP analysis to isolate differentially expressed genes in fertile and sterile buds of the two-.. Read More»

Genet. Mol. Res. 10(4):
2011.December.5.8
DOI:
10.4238/2011.December.5.8
Human Genetics   Research Article

Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study

Authors: A.L. Miranda-Vilela, A.K. Akimoto, P.C.Z. Alves, L.B. Ferreira, G.S. Lordelo, J.G.M. Melo, C.K. Grisolia, S.F. Oliveira and M.N. Klautau-Guimar�£es

Essential hypertension is a complex and multifactorial trait; genetic and environmental factors interact to produce the final phenotype. Studies have demonstrated association of hypertension with varied gene polymorphisms. However, demonstration of common genetic causes in the general population remains elusive. We investigate.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr973
DOI:
10.4238/vol9-4gmr973
Human Genetics   Research Article

Diversity of platelet function and genetic polymorphism in clopidogrel-treated Chinese patients

Authors: B. Sun, J. Li, M. Dong, L. Yang, C. Wu, L. Zhu and Y.L. Cong

We investigated the correlation between genetic polymorphisms of cytochrome P450 enzyme genes and the outcome of clopidogrel treatment in 118 coronary disease patients after percutaneous coronary intervention at the Chinese PLA General Hospital. Patients were divided into an ischemia event relapse group (IERG) and a non-IERG group (NIERG) based on relapse.. Read More»

Genet. Mol. Res. 14(1):
2015.February.13.22
DOI:
10.4238/2015.February.13.22
Plant Genetics   Research Article

Molecular identification of Fusarium species isolated from transgenic insect-resistant cotton plants in Mexicali valley, Baja California

Authors: T. Gonzalez-Soto, D. Gonz�¡lez-Mendoza, R. Troncoso-Rojas, A. Morales-Trejo, C. Cece�±a-Duran, A. Garcia-Lopez and O. Grimaldo-Juarez

Cotton production in the Mexicali valley is adversely affected by wilt and root rot disease associated with Fusarium species. In the present study, we sought to isolate and identify the Fusarium species in the rhizosphere of transgenic insect-resistant cotton plants grown in the Mexicali valley. Our analyses isolated four nati.. Read More»

Genet. Mol. Res. 14(4):
2015.October.2.7
DOI:
10.4238/2015.October.2.7
Plant Genetics   Research Article

Genetic diversity in wild species of passion fruit (Passiflora trintae) based on molecular markers

Authors: C.B.M. Cerqueira-Silva, C.B. Cardoso-Silva, E.S.L. Santos, L.D.H.C.S. Concei�§�£o, A.S. Pereira, A.C. Oliveira and R.X. Corr�ªa

In spite of the importance of and the considerable variability observed in Passiflora (Passifloraceae), little is known about the genetic diversity of most of the species of this genus. We evaluated the genetic diversity by RAPD markers in 18 genotypes of Passiflora trintae. The 15 primers generated 112 markers, 84% of which w.. Read More»

Genet. Mol. Res. 9(4):
vol9-4gmr875
DOI:
10.4238/vol9-4gmr875
Human Genetics   Research Article

Genetic diversity analysis of Capparis spinosa L. populations by using ISSR markers

Authors: C. Liu, G.P. Xue, B. Cheng, X. Wang, J. He, G.H. Liu and W.J. Yang

Capparis spinosa L. is an important medicinal species in the Xinjiang Province of China. Ten natural populations of C. spinosa from 3 locations in North, Central, and South Xinjiang were studied using morphological trait inter simple sequence repeat (ISSR) molecular markers to assess the genetic diversity and population structure. In this study, the 10 IS.. Read More»

Genet. Mol. Res. 14(4):
2015
DOI:
10.4238/2015