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Gastric Cancer

Human Genetics   Research Article

IL-17 rs2275913 genetic variation contributes to the development of gastric cancer in a Chinese population

Authors: B.L. Xu, Y.T. Li, S.X. Dong, J. Qi, H.M. Feng, L. Zi and D.Y. Yang

The purpose of this hospital-based case-control study was to assess whether the interleukin (IL)-17 rs2275913 genetic variation can influence susceptibility to gastric cancer. Samples from a total of 202 gastric cancer patients and 237 controls were collected from the Linyi People’s Hospital between March 2013 and March .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027756
DOI:
10.4238/gmr.15027756
Human Genetics   Research Article

Association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population

Authors: R.J. Li, M. Li, G.J. Liu, Y.W. Guo, H. Bai, P. Xiao and J.Z. Mei

We conducted a hospital-based case-control study to investigate the association between 3 common SNPs in the ERCC5 gene (rs1047768, rs751402, and rs17655) and the risk of developing gastric cancer. Between January 2013 and December 2014, samples were collected from 216 gastric cancer patients and 216 control subjects. ERCC5 rs1047768, rs751402, and rs1765.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017510
DOI:
10.4238/gmr.15017510
Human Genetics   Research Article

Genetic variability of DNA repair mechanisms in chemotherapy treatment outcome of gastric cancer patients

Authors: G. Zhong, H.K. Li, T. Shan and N. Zhang

We investigate whether three common polymorphisms in ERCC1 and ERCC2 are predictor factors for the chemotherapy response, as well as the clinic outcome of patients with gastric cancer. Between May 2011 and May 2013, 263 patients with gastric cancer who were newly diagnosed by histopathology were enrolled in our study. Genotyping of the ERCC1 rs11615 and r.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.22
DOI:
10.4238/2015.December.16.22
Medical Genetics   Research Article

Prognostic value of miR-141 downregulation in gastric cancer

Authors: Y.B. Lu, J.J. Hu, W.J. Sun, X.H. Duan and X. Chen

Previous research has shown that microRNA-141 (miR-141) expression levels are associated with survival in several types of cancer. In the present study, we investigated the clinical significance and prognostic value of miR-141 in gastric cancer. Paired tissue specimens (tumor and adjacent normal mucosa) from 95 patients with gastric cancer were obtained a.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.31
DOI:
10.4238/2015.December.16.31
Human Genetics   Research Article

Lack of association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population

Authors: J.J. Lu, H.Q. Zhang, P. Mai, X. Ma, X. Chen, Y.X. Yang and L.P. Zhang

We conducted a case-control study to assess the association between single nucleotide polymorphisms in the ERCC5 promoter (rs2094258 and rs751402) and development of gastric cancer in a Chinese population. This investigation included 184 patients with pathologically diagnosed gastric cancer and 206 healthy subjects recruited b.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027779
DOI:
10.4238/gmr.15027779
Human Genetics   Research Article

Association between XPG gene polymorphisms and development of gastric cancer risk in a Chinese population

Authors: Y.B. Feng, D.Q. Fan, J. Yu and Y.K. Bie

We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms (SNPs) in the xeroderma pigmentosum complementation group G (XPG) gene (rs2094258, rs751402 and rs17655) in the development of gastric cancer in a Chinese population. Between January 2012 and December 2014, samples from a .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027877
DOI:
10.4238/gmr.15027877
Human Genetics   Research Article

Association between ERCC5 gene polymorphisms and gastric cancer risk

Authors: B.W. Guo, L. Yang, R. Zhao and S.Z. Hao

We investigate the role of ERCC5 gene polymorphisms (rs17655 and rs751402) in the development of gastric cancer in a Chinese population. A total of 142 gastric cancer patients whose diagnoses were confirmed by pathology, and 274 control subjects were recruited from Tangshan Gongren Hospital between March 2013 and March 2015. G.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027828
DOI:
10.4238/gmr.15027828
Medical Genetics   Research Article

Impact of early enteral and parenteral nutrition on prealbumin and high-sensitivity C-reactive protein after gastric surgery

Authors: B. Li, H.-Y. Liu, S.-H. Guo, P. Sun, F.-M. Gong and B.-Q. Jia

We investigated the impact of early enteral nutrition (EEN) and parenteral nutrition (PN) on prealbumin (PA) and highsensitivity C-reactive protein (hs-CRP) in patients after gastric cancer surgery. Sixty-eight selected patients undergoing gastric cancer surgery were randomly divided into the EEN (N = 34) and PN (N = 34) groups. Body weight (BW), serum al.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.6
DOI:
10.4238/2015.June.29.6
Medical Genetics   Research Article

Impact of early postoperative enteral nutrition on clinical outcomes in patients with gastric cancer

Authors: B. Li, H.Y. Liu, S.H. Guo, P. Sun, F.M. Gong and B.Q. Jia

The impact of early enteral nutrition (EEN) on clinical outcomes of gastric cancer patients was investigated. Three hundred patients undergoing gastric cancer surgery from July 2010 to May 2014 were randomly divided into experimental and control groups (n = 150/ group). Experimental group patients received enteral nutrition in water during the early posto.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.7
DOI:
10.4238/2015.June.29.7
Human Genetics   Research Article

Genetic variability of ERCC1 and ERCC2 influences treatment outcomes in gastric cancer

Authors: W.H. Yu, Y.X. Wang, J.Q. Guo, Y.L. Wang, J.S. Zheng and K.X. Zhu

We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer. A total of 346 patients with gastric cancer were recruited between May 2009 and May 2012. Single nucleotide polymorphism genotyping was performed using the Sequenom MassARR.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.25
DOI:
10.4238/2015.December.21.25