Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil
Authors: J. Coser, T. da Rocha Boeira, D. Simon, A.S. Kazantzi Fonseca, N. Ikuta and V.R. Lunge
Human papillomavirus (HPV) infection is a common viral sexually transmitted infection and the main cause of cervical cancer in women worldwide. Epidemiological data on the prevalence of HPV in a given population is essential for the establishment of effective prevention strategies. The aim of this study was to determine HPV prevalence in women who attende.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.19.3
- DOI:
- 10.4238/2013.February.19.3
Variability and performance evaluation of introgressed Nigerian dura x Deli dura oil palm progenies
Authors: A. Noh, M.Y. Rafii, A. Mohd Din, A. Kushairi, A. Norziha, N. Rajanaidu, M.A. Latif and M.A. Malek
Twelve introgressed oil palm (Elaeis guineensis) progenies of Nigerian dura x Deli dura were evaluated for bunch yield, yield attributes, bunch quality components and vegetative characters at the Malaysian Palm Oil Board Research Station, in Keratong, Pahang, Malaysia. Analysis of variance revealed significant to highly signif.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.15
- DOI:
- 10.4238/2014.April.3.15
Transcriptome network analysis of potential candidate genes for heart failure
Authors: J. Chen, H.Y. Wang and C.Y. Zeng
The purpose of this study was to examine the hypothesis that a transcriptome network can be developed through a set of transcription factors regulated by the expression of various genes induced by dilated cardiomyopathy can be identified and modulated to respond to heart failure. We searched for significant pathways related to dilated cardiomyopathy using.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.7
- DOI:
- 10.4238/2013.October.18.7
Construction of single-chain variable fragment antibodies against MCF-7 breast cancer cells
Authors: A.A. Zuhaida1, A.M. Ali1,2, S. Tamilselvan3, N.B. Alitheen3, M. Hamid1,4, A.M. Noor2 and S.K. Yeap1
A phage display library of single chain variable fragment (scFv) against MCF-7 breast cancer cells was constructed from C3A8 hybridoma cells. RNA from the C3A8 was isolated, cDNA was constructed, and variable heavy and light immunoglobulin chain gene region were amplified using PCR. The variable heavy and light chain gene regions were combined with flexib.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.5
- DOI:
- 10.4238/2013.November.18.5
N-terminal functional region of the invariant chain efficiently targets the binding of a CTL epitope to MHC class I molecules during cross-presentation
Authors: C. Wu, D.G. Zhang, F.F. Chen, X.L. Liu, S.J. Liu and W.Y. Yu
Cross-presentation (CP) is important for priming T cell responses to many viral, bacterial, and tumor antigens. Here, we designed two Ii mutants, based on evidence that the invariant chain (Ii, also named CD74) binds newly synthesized MHC class I molecules with the class II-associated invariant chain peptide (CLIP) region of I.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.16
- DOI:
- 10.4238/2014.April.3.16
Molecular characterization of high performance inbred lines of Brazilian common beans
Authors: P.C.B. Cardoso, M.M. Veiga, I.P.P. de Menezes, P.A.M.R. Valdisser, T.C.O. Borba, L.C. Melo, M.J. Del Peloso, C. Brondani and R.P. Vianello
The identification of germplasm genetic variability in breeding programs of the common bean (Phaseolus vulgaris) is essential for determining the potential of each combination of parent plants to obtain superior genotypes. The present study aimed to estimate the extent of genetic diversity in 172 lines and cultivars of the common bean by integrating five .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.6.4
- DOI:
- 10.4238/2013.February.6.4
Colorectal cancer susceptibility variants alter risk of breast cancer in a Chinese Han population
Authors: W. Wei, M. Jiang, L. Luo, Z. Li, P. Wang and W.Q. Dong
Recent genome wide association studies (GWAS) and candidate gene studies have revealed many novel loci associated with colorectal cancer susceptibility. We evaluated the effect of these colorectal cancer-associated variants on the risk of breast cancer in a Chinese Han population. Seven single nucleotide polymorphisms (SNPs) (rs3856806 in PPARG, rs7014346.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.14
- DOI:
- 10.4238/2013.December.4.14
Universal primers to amplify the complete mitochondrial 12S rRNA gene in marine fish species
Authors: X.X. Jin, S.L. Zhao, R.X. Wang
A pair of new universal 12S mitochondrial rRNA gene primers was designed through multiple alignment analysis of the mitochondrial tRNAPhe and the 5’ region of 16S mitochondrial rRNA genes of different kinds of fishes. The primers were successfully used to amplify an expected product fragment of about 1.2 kb from various marine fish species, and the .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.6
- DOI:
- 10.4238/2013.October.15.6
Interleukin-1�² +3954 polymorphisms and risk of external apical root resorption in orthodontic treatment: A meta-analysis
Authors: F.-L. Wu, L.-Y. Wang, Y.-Q Huang, W.-B. Guo, C.-D. Liu and S.-G. Li
The purpose of this meta-analysis was to determine whether genetic variants of the interleukin-1β[+3954 C>T (rs1143634)] (IL-1β +3954 C>T) gene polymorphisms were associated with orthodontic external apical root resorption (EARR). A meta-analysis was carried out using data entered into the PubMed and Embase electronic databases before Octo.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.6
- DOI:
- 10.4238/2013.October.18.6
Prevalence of diabetes and impaired fasting glucose in Uygur children of Xinjiang, China
Authors: J. Zhang1, Y.T. Ma1, X. Xie1, Y.N. Yang1, F. Liu2, X.M. Li1, Z.Y. Fu1, X. Ma1, B.D. Chen2, Y.Y. Zheng1, Z.X. Yu1 and Y. Chen1
This study was designed to estimate the prevalence of diabetes and impaired fasting glucose (IFG) in Xinjiang children in western China. Data were obtained from the Chun-Miao Project, a community-based, cross-sectional study designed to investigate the prevalence and risk factors of diabetes in children of the Chinese Uygur population in Xinjiang from Feb.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.13
- DOI:
- 10.4238/2013.October.24.13