Analysis of p53 gene polymorphism (codon 72) in symptomatic patients with atherosclerosis
Authors: M.H. Lagares, K.S.F. Silva, A.M. Barbosa, D.A. Rodrigues, I.R. Costa, J.V.M. Martins, M.P. Morais, F.L. Campedelli and K.K.V.O. Moura
Atherosclerosis is a multifactorial pathological disease that alters the morphology and function of arterial walls. The atheroma growth leads to vessel hardening and lumen narrowing, limiting the blood flow. The atheroma plaque can eventually break, expose highly thrombogenic material and lead to platelet activation and subseq.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039721
- DOI:
- 10.4238/gmr16039721
Correlation study of resistance components in the selection of Capsicum genotypes resistant to the fungus Colletotrichum gloeosporioides
Authors: A.C. Maracahipes, J.W.S. Correa, P.E. Teodoro, K.L. Ara�ºjo, M.A.A. Barelli and L.G. Neves
Anthracnose is among the major diseases of the Capsicum culture. It is caused by different species of the genus Colletotrichum, which may result in major damages to the cultivation of this genus. Studies aiming to search for cultivars resistant to diseases are essential to reduce financial and agricultural losses. The objectiv.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039720
- DOI:
- 10.4238/gmr16039720
Antioxidant activity and chemical composition of oleoresin from leaves and flowers of Brunfelsia uniflora
Authors: L.F. Jorge, A.B. Meniqueti, R.F. Silva, K.A. Santos, E.A. Da Silva, J.E. Gon�§alves, C.M. De Rezende, N.B. Colauto, Z.C. Gazim and G.A. Linde
In this study, the temperature and pressure of supercritical CO2 extraction were evaluated to obtain oleoresin of Brunfelsia uniflora leaves and flowers. The oleoresin compounds were identified by gas chromatography-mass spectrometry. The antioxidant activity was evaluated by three different methods. The highest oleoresin yiel.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039714
- DOI:
- 10.4238/gmr16039714
Analysis of Mendelian inheritance and genetic linkage in microsatellite loci of Eucalyptus urophylla S.T. Blake
Authors: S. Pupin, L.N. Rosse, I.C.G. Souza, J. Cambuim, C.L. Marino, M.L.T. Moraes and A.M. Sebbenn
Eucalyptus urophylla is an important species in the Brazilian forest sector due to its rapid growth rates and resistance to disease. The aim of this study was to verify Mendelian inheritance, genetic linkage, and genotypic disequilibrium for 15 microsatellite loci, with the goal of producing a robust set of genetic markers. Me.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039713
- DOI:
- 10.4238/gmr16039713
Isolation and characterization of polymorphic microsatellite markers for the chub mackerel (Scomber japonicus) and cross-species amplification in the blue mackerel (S. australasicus)
Authors: F.F. Chen, C.Y. Ma, L.P. Yan, H. Zhang, W. Wang, Y. Zhang and L.B. Ma
In this study, 10 polymorphic microsatellite markers were developed in Scomber japonicus and were examined on 30 individuals collected from the North Pacific. The number of alleles per locus ranged from 4 to 17. The observed and expected heterozygosities per locus ranged from 0.2759 to 0.8621 and from 0.43071 to 0.9177, respec.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039712
- DOI:
- 10.4238/gmr16039712
First record of soybean stem fly Melanagromyza sojae (Diptera: Agromyzidae) in Paraguay confirmed by molecular evidence
Authors: J.V.C. Guedes, J.A. Arnemann, L.E. Curioletti, L.M. Burtet, M.L. RamÃ?Ârez-Paredes, D. Noschang, F. Irala de Oliveira and W.T. Tay
We provided the first scientific record of Melanagromyza sojae (Zehntner, 1900), through molecular characterization of partial mtDNA COI gene, that confirms the occurrence of this pest in Paraguay. Previously reported in Brazil, an outbreak of larvae of M. sojae known as the soybean stem fly (SSF) that belongs to the family Ag.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039707
- DOI:
- 10.4238/gmr16039707
First cytotoxic, genotoxic, and antigenotoxic assessment of Euterpe oleracea fruit oil (aÃ?§aÃ?Â) in cultured human cells
Authors: E.S. Marques, M.S.F. Tsuboy, J.C.T. Carvalho, P.C.P. Rosa, F.F. Perazzo, I.O.M. Gaiv�£o and E.L. Maistro
Euterpe oleracea Mart., popularly known as “açaí”, is a tropical fruit from the Amazon region where it has considerable economic importance. Açaí has been used as food and for several medicinal purposes. Despite the widespread use of this fruit, there is a lack of data regarding the safe.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039700
- DOI:
- 10.4238/gmr16039700
Analysis of genetic diversity of Hyptis pectinata (L.) Poit. plants using ISSR markers
Authors: R.B. Feitosa-Alcantara, A.V.C. Silva, A.F. Blank, C.S. Almeida, S.V. Alvares-Carvalho and M.F. Arrigoni-Blank
Hyptis pectinata, popularly known as ‘sambacaitá’ or ‘canudinho’, is a medicinal and aromatic species widely used in the Brazilian Northeast. In Sergipe, the excessive extraction of natural resources may reduce the genetic variability of native plants. Thus, molecular markers have frequently been.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039603
- DOI:
- 10.4238/gmr16039603
Physiological and enzymatic alterations in sesame seeds submitted to different osmotic potentials
Authors: R.M.O. Pires, M.A.B. Ã?Â?vila, D.G. Leite, H.O. Santos, G.A. Souza and E.V.R. Von Pinho
With the imminence of global climate changes that affect the temperature and the rainfall uniformity, it is growing the concern about the adaptation of crops to the water deficit. Thus, the objective of this study was to evaluate alterations in physiological and enzymatic mechanisms during the germination process of sesame see.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039425
- DOI:
- 10.4238/gmr16039425
miR-367 promotes uveal melanoma cell proliferation and migration by regulating PTEN
Authors: J.W. Ling, P.R. Lu, Y.B. Zhang, S. Jiang and Z.C. Zhang
We aimed to investigate the biological role of miR-367 in uveal melanoma cell growth and migration, and the underlying mechanism responsible. Quantitative real-time polymerase chain reaction was performed to evaluate miR-367 expression in uveal melanoma tissue samples and cell lines. A miR-367 mimic, miR-367 inhibitor, and neg.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039067
- DOI:
- 10.4238/gmr16039067