Methylation-sensitive amplified polymorphism-based genome-wide analysis of cytosine methylation profiles in Nicotiana tabacum cultivars
Authors: J. Jiao, J. Wu, Z. Lv, C. Sun, L. Gao, X. Yan, L. Cui, Z. Tang, B. Yan and Y. Jia
This study aimed to investigate cytosine methylation profiles in different tobacco (Nicotiana tabacum) cultivars grown in China. Methylation-sensitive amplified polymorphism was used to analyze genome-wide global methylation profiles in four tobacco cultivars (Yunyan 85, NC89, K326, and Yunyan 87). Amplicons with meth.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.6
- DOI:
- 10.4238/2015.November.25.6
Classification of colon cancer based on the expression of randomly selected genes
Authors: X.H. Tan, R. Cheng, H.P. Hu and Y.P. Bai
In order to ascertain the relationship between gene expression and colon cancer localization, a classification method based on random gene selection and a self-organizing map network is proposed. Different numbers of genes were selected randomly from 54,675 genes of 53 colon cancer patients in stage union for international can.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.6
- DOI:
- 10.4238/2015.October.19.6
Thymidylate synthase enhancer region polymorphism not related to susceptibility to acute lymphoblastic leukemia in the Kashmir population
Authors: F.H. Nazki, A. Masood, M.A. Banday, A. Bhat and B.A. Ganai
Thymidylate synthase (TS) is a crucial enzyme in folate metabolism and plays a vital role in DNA synthesis and repair. The most common polymorphism in TS is a unique double (2R) or triple (3R) 28-bp tandem repeat sequence in the enhancer region of the TS gene (TSER). This genetic variation in TSER has been widely investigated .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.6
- DOI:
- 10.4238/2012.April.10.6
Association of adiponectin gene polymorphisms with hypertensive disorder complicating pregnancy and disorders of lipid metabolism
Authors: Y. Wang, R.X. Liu and H. Liu
The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) in APM1 contribute to disorders of lipid metabolism in hypertensive disorder complicating pregnancy (HDCP). The study included 178 pregnant women with HDCP and 243 healthy pregnant controls. Using PCR-restriction fragment length poly.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.9
- DOI:
- 10.4238/2015.November.25.9
Chromosomal evolution in the pallescens group (Hemiptera, Triatominae)
Authors: K.C.C Alevi, A. Ravazi, M.F. Franco-Bernardes, J.A. Rosa and M.T.V. Azeredo-Oliveira
Rhodnius colombiensis, in conjunction with R. pallescens and R. ecuadoriensis, forms the monophyletic pallescens group. Cytogenetic analyses of these closely related species would further our understanding of the taxonomy and evolution of this group. In this study, R. colombiensis was cytogenetically analyzed, and the results .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.9
- DOI:
- 10.4238/2015.October.19.9
Genetic structure and diversity analysis of the primary gene pool of chickpea using SSR markers
Authors: P. Choudhary, S.M. Khanna, P.K. Jain, C. Bharadwaj, J. Kumar, P.C. Lakhera and R. Srinivasan
Members of the primary gene pool of the chickpea, including 38 accessions of Cicer arietinum, six of C. reticulatum and four of C. echinospermum grown in India were investigated using 100 SSR markers to analyze their genetic structure, diversity and relationships. We found considerable diversity, with a mean of 4.8 alleles per.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.5
- DOI:
- 10.4238/2012.April.10.5
Association of the CYP4F2 rs2108622 genetic polymorphism with hypertension: a meta-analysis
Authors: X.-H. Luo, G.-R. Li and H.-Y. Li
Previous case-control studies on the relationship between the CYP4F2 gene rs2108622 polymorphism and hypertension have produced contrasting results. In this study, we aimed to further evaluate the relationship between the CYP4F2 gene rs2108622 polymorphism and hypertension. We selected four case-control studies related to the .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.1
- DOI:
- 10.4238/2015.November.25.1
Characterization of ESTs from black locust for gene discovery and marker development
Authors: J.X. Wang, C. Lu, C.Q. Yuan, B.B. Cui, Q.D. Qiu, P. Sun, R.Y. Hu, D.C. Wu, Y.H. Sun and Y. Li
Black locust (Robinia pseudoacacia L.) is an ecologically and economically important species. However, it has relatively underdeveloped genomic resources, and this limits gene discovery and marker-assisted selective breeding. In the present study, we obtained large-scale transcriptome data using a next-generation sequencing pl.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.12
- DOI:
- 10.4238/2015.October.19.12
Molecular characteristics and cloning of two pepper genes AN2 and UPA20
Authors: H.X. Chen, H. Jiang, J.L. Huo, J.F. Wen, H.S. Zhu, C.H. Ma, H. Zhou, J.H. Lv and M.H. Deng
The complete coding sequences (CDSs) of “Yunnan Purple Pepper No.1” (Capsicum annuum L.) AN2 and UPA20 genes were amplified using the reverse transcriptase polymerase chain reaction on the basis of the conserved sequence information of some Solanaceae plants and known highly homologous pepper expressed sequence tags. The nucleotide sequence an.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.17.6
- DOI:
- 10.4238/2014.January.17.6
Reproductive outcomes in recurrent pregnancy loss associated with a parental carrier of chromosome abnormalities or polymorphisms
Authors: Y. Dong, L.L. Li, R.X. Wang, X.W. Yu, X. Yun and R.Z. Liu
The subsequent reproductive outcomes in couples with a history of recurrent pregnancy loss (RPL) associated with chromosome abnormalities or polymorphisms are generally not reported in China. Many RPL carrier couples have decided not to have children. The present study recorded the subsequent delivery, miscarriage, and unpregn.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.17.4
- DOI:
- 10.4238/2014.January.17.4