Table of Contents | Genet. Mol. Res.2016(1)
GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population
Authors: M.N. Khabaz1, T. Nedjadi2, M.A. Gari3, J.A. Al-Maghrabi4, H.M. Atta5,M. Bakarman6 and Z.J. Gazzaz7
The enzyme glutathione S-transferase Mu 1 (GSTM1) is encoded by the GSTM1 gene. Polymorphisms in GSTM1 affect the detoxifying function of the enzyme variants. This forms the basis of the debate about the impact of the GSTM1 null/present genotype on colorectal carcinoma risk. We tested the potential influence of GSTM1 polymorphisms on the development of co.. Read More»
Genet. Mol. Res. 15(1): gmr.15017551
DOI: 10.4238/gmr.15017551
Haplotypes of qGL3 and their roles in grain size regulation with GS3 alleles in rice
Authors: Y.D. Zhang1,2, Z. Zhu1, Q.Y. Zhao1,2, T. Chen1, S. Yao1, L.H. Zhou1, L. Zhao1,C.F. Zhao1 and C.L. Wang1,2
Grain size is an important trait that directly influences rice yield. The qGL3 and GS3 genes are two putative regulators that play a role in grain size determination. A single rare nucleotide substitution (C→A) at position 1092 in exon 10 of qGL3 might be responsible for variations in grain size. However, little is known about the haplotype variation.. Read More»
Genet. Mol. Res. 15(1): gmr.15017587
DOI: 10.4238/gmr.15017587
Evaluation of associations between single nucleotide polymorphisms in the FRMD3 and CARS genes and diabetic nephropathy in a Kuwaiti population
Authors: S. Al-waheeb1, M. Alwohhaib2, A. Abdelghani3, S. Al-Sharrah2, E. Al-Shafey4,A. Al-Sahow4, N. Alyatama5, A.A. Dashti2 and N. Hussain3
Diabetic nephropathy is the leading cause of end-stage kidney disease in the world. Many single nucleotide polymorphisms (SNPs) have been associated with diabetic nephropathy. SNPs at the 4.1 protein ezrin, radixin, moesin domain 3 (FRMD3) and cysteinyl t-RNA synthetase (CARS) genes have a well-established relationship with diabetic nephropathy. However, .. Read More»
Genet. Mol. Res. 15(1): gmr.15017619
DOI: 10.4238/gmr.15017619
De novo assembly and characterization of Gleditsia sinensis transcriptome and subsequent gene identification and SSR mining
Authors: S. Han, Z. Wu, X. Wang, K. Huang, Y. Jin, W. Yang and H. Shi
Gleditsia sinensis is a Chinese native deciduous tree with a high economic and medicinal value. However, there is limited knowledge on the molecular processes responsible for the medical properties of this species owing to lack of bioinformatic resources such as available whole-genome sequences. In the present study, RNA sequencing data were used to analy.. Read More»
Genet. Mol. Res. 15(1): gmr.15017740
DOI: 10.4238/gmr.15017740
Developmental methylation pattern regulates porcine GPR120 expression
Authors: H.M. Wang*, J.D. Ma*, L. Jin, Y.H. Liu, T.D. Che, M.Z. Li and X.W. Li
DNA methylation is an important component of the epigenetic machinery and plays a critical role in transcriptional regulation. It mostly occurs in CpG abundant regions, known as CpG islands (CGIs). G protein-coupled receptor 120 (GPR120) functions as an omega-3 fatty acid receptor and is involved in multiple-biological processes, including lipogenesis. He.. Read More»
Genet. Mol. Res. 15(1): gmr.15014240
DOI: 10.4238/gmr.15014240
Overexpression of NaKR3 enhances salt tolerance in Arabidopsis
Authors: Q. Luo1,2, Z. Zhao1, D.K. Li1, Y. Zhang1, L.F. Xie1, M.F. Peng1, S. Yuan3 and Y. Yang1,2
Salinity is a major abiotic stress in agriculture. Here, we report that SODIUM POTASSIUM ROOT DEFECTIVE3 (NaKR3), which encodes a heavy metal-associated domain protein, is involved in salt tolerance in Arabidopsis. The results of quantitative reverse transcription-polymerase chain reaction analysis revealed that NaKR3 was induced by high salinity and osmo.. Read More»
Genet. Mol. Res. 15(1): gmr.15016378
DOI: 10.4238/gmr.15016378
Molecular cloning, tissue expression pattern, and copy number variation of porcine SCUBE3
Authors: X. Liu*, L.G. Wang*, L.C. Zhang, H. Yan, K.B. Zhao, J. Liang, N. Li, L. Pu,T. Zhang and L.X. Wang
The signal peptide CUB EGF-like domain-containing protein 3 (SCUBE3) gene is a member of SCUBE gene family and plays important roles in bone cell biology and the determination of limb bone length. In this study, the full-length transcript of porcine SCUBE3 was cloned using reverse transcription-polymerase chain reaction and rapid amplification of cDNA end.. Read More»
Genet. Mol. Res. 15(1): gmr.15017010
DOI: 10.4238/gmr.15017010
Correlation between adiponectin and hemorrhagic shock in mice
Authors: X. Gong, Y. Liu, S. Yao, J.F. Zheng, F. Wan, X.D. Xiang and X.P. Chai
The aim of this study was to explore the relationship between adiponectin (ADPN) and hemorrhagic shock (HS) and the recovery after HS. This is significant for further understanding of the pathophysiological processes of HS and the development of better treatments. In total, 72 male C57BL/6 mice were assigned randomly to three groups: control, HS, and reco.. Read More»
Genet. Mol. Res. 15(1): gmr.15017037
DOI: 10.4238/gmr.15017037