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Z. Ma

Publications of : Z. Ma
Human Genetics   Research Article

Association of endothelin-1 gene polymorphisms with essential hypertension in a Chinese population

Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor and is involved in several vascular disorders such as hypertension. Its strong interaction with other vasoactive hormone systems suggests that the ET-1 gene (EDN1) is a potential candidate molecule that influences the risk of developing hypertension. Recently, two single nucleotide polymorphisms in ED.. Read More»

Genet. Mol. Res. 16(3): gmr16037446

DOI: 10.4238/gmr16037446

Animal Genetics   Research Article

Screening and analyzing genes associated with Amur tiger placental development

    Q. Li, T.F. Lu, D. Liu, P.F. Hu, B. Sun, J.Z. Ma, W.J. Wang, K.F. Wang, W.X. Zhang, J. Chen, W.J. Guan, Y.H. Ma and M.H. Zhang

The Amur tiger is a unique endangered species in the world, and thus, protection of its genetic resources is extremely important. In this study, an Amur tiger placenta cDNA library was constructed using the SMART cDNA Library Construction kit. A total of 508 colonies were sequenced, in which 205 (76%) genes were annotated and mapped to 74 KEGG pathways, including 29.. Read More»

Genet. Mol. Res. 13(3): 2014.September.26.25

DOI: 10.4238/2014.September.26.25

Human Genetics   Research Article

Effects of sodium lactate Ringer’s injection on transfection of human protein kinase C-α antisense oligonucleotide in A549 lung cancer cells

    Z.H. Wang, W.W. Sun, Y.L. Han and Z. Ma

In the present study, we evaluated the effects of four solutions [Dulbecco’s modified Eagle’s medium (DMEM), sodium lactate Ringer’s injection (SLRI), phosphate-buffered saline (PBS), and NaCl] on the transfection of the human protein kinase C-a antisense oligonucleotide (PKC-a ASO) aprinocarsen in human lung carcinoma A549 cells. Specifically, SLRI, DMEM, PBS, or NaCl were us.. Read More»

Genet. Mol. Res. 15(3): gmr.15037650

DOI: 10.4238/gmr.15037650

Human Genetics   Research Article

The genetic variant rs401681C/T is associated with the risk of non-small cell lung cancer in a Chinese mainland population

    H. Wang Y. Zhao J. Ma G. Zhang Y. Mu G. Qi Z. Fang L. Wang Q. Fan Z. Ma

Although lung cancer (LC) is a highly environmentally associated disease, genetic factors are also thought to play a role in this disease. In recent years, genome-wide association studies have identified various susceptible genetic regions for LC. Herein, we used high-resolution melting analysis to genotype 2 significant single nucleotide polymorphisms previously reported in Caucasians, that is.. Read More»

Genet. Mol. Res. 12(1): 2013.January.22.5

DOI: 10.4238/2013.January.22.5

Bioinformatics   Research Article

Psychogenetics of Turner syndrome: an investigation of 28 subjects and respective controls using the Bender test and Piagetian scales

    F.C.F. Ricardi, L.L. Zaia, I. Pellegrino-Rosa, J.T. Rosa, O.Z. Mantovani de Assis and P.H. Saldanha

Piagetian scales and the Bender visual motor gestalt test (BT) were applied to 28 subjects with universal 45,X Turner syndrome (TS), and their respective controls, in order to investigate their cognitive performance. Dermatoglyphics were also analyzed to obtain clues concerning embryological changes that may have appeared during development of the nervous system and.. Read More»

Genet. Mol. Res. 9(3): vol9-3gmr815

DOI: 10.4238/vol9-3gmr815

Medical Genetics   Research Article

Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia

    L.P. Wang, X.Y. Zhang, N. Liu, Z.Z. Ma and D.S. Fang

The aim of this study was to investigate the clinical effect of western medicine therapy assisted by Ginkgo biloba tablets (GBT) in patients with vascular cognitive impairment with no dementia (VCIND). Eighty patients with VCIND were randomly divided into two groups: the conventional treatment group (control group) and the combined treatment group. The conventional treatment group was provided .. Read More»

Genet. Mol. Res. 14(2): 2015.May.11.22

DOI: 10.4238/2015.May.11.22

Human Genetics   Research Article

Genetic diversity in somatic mutants of grape (Vitis vinifera) cultivar Italia based on random amplified polymorphic DNA

    S.H.Z. Maia C.A. Mangolin S.A.O. Collet M.F.P.S. Machado

Random amplified polymorphic DNA (RAPD) markers were used to detect polymorphism and to examine relationships among four table grape clones from northwestern Paraná, in southern Brazil. The 10 primers used for RAPD fingerprints generated 126 reproducible fragments, of which 63, 68, 76, and 72 were polymorphic in cultivars Italia, Rubi, Benitaka, and Brasil, r.. Read More»

Genet. Mol. Res. 8(1): vol8-1gmr536

DOI: 10.4238/vol8-1gmr536

Human Genetics   Research Article

Postpartum pelvic floor function performance after two different modes of delivery

    H. Li, R.F. Wu, F. Qi, A.M. Xiao, Z. Ma, Y. Hu, W.Y. Zhang, W. Li and Z.C. Wang

This study investigated the incidences of urinary incontinence and pelvic organ prolapse as well as pelvic floor muscle strength after cesarean section and vaginal delivery. From June 2010 to July 2011, 149 puerpera in Shenzhen Hospital, Peking University, were divided into the cesarean section group (N = 66) and the vaginal delivery group (N = 83). Postpartum urinary incontinence analysis, pel.. Read More»

Genet. Mol. Res. 14(2):


Human Genetics   Research Article

Selection of reference genes in canine uterine tissues

    M. Du, X. Wang, Y.W. Yue, P.Y. Zhou, W. Yao, X. Li, X.B. Ding,X.F. Liu, H. Guo and W.Z. Ma

Real-time quantitative polymerase chain reaction (RT-qPCR) is usually employed in gene expression studies in veterinary research, including in studies on canine pyometra. Canine pyometra is a common clinical disease in bitches. When using RT-qPCR, internal standards, such as reference genes, are necessary to investigate relative gene expression by quantitative measu.. Read More»

Genet. Mol. Res. 15(2): gmr.15028138

DOI: 10.4238/gmr.15028138

Animal Genetics   Research Article

Investigations on the genomic diversity of OXA from isolated Acinetobacter baumannii

    Z. Ma, L.Q. Zhou, H. Wang and L.P. Luo

We distinguished the four OXA-type carbapenemase subgroup alleles present in 120 strains of Acinetobacter baumannii by using polymerase chain reaction (PCR) and investigated the distributions of the OXA subgroups in clinically isolated samples. Amplification of the OXA genes blaOXA-23, blaOXA-24, blaOXA-51, and blaOXA-58 was performed by multiplex PCR. Antibiotics susceptibility test was conduc.. Read More»

Genet. Mol. Res. 14(4): 2015.November.18.36

DOI: 10.4238/2015.November.18.36