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Publications of : M.G.C. Carvalho
Human Genetics   Case Reports

Glioblastoma in a 20-year-old female patient after Chikungunya infection

We describe the case of a 20-year-old female patient who died 4 months after the diagnosis of a glioblastoma (GBM). The tumor emerged nearly a month after a Chikungunya (CHIKV) infection and displayed positivity to Citomegalovirus (CMV) DNA. The immunohistochemical studies revealed GFAP positivity in rare cells, IDH-1 positive, vimentin positive, ATRX positive, Ki-67 positive in 35% of neoplast.. Read More»

Genet. Mol. Res. 18(1):

Human Genetics   Research Article

Epstein-Barr virus DNA associated with gastric adenocarcinoma and adjacent non-cancerous mucosa in patients from Manaus, Brazil

    P.F. de Aquino P.C. Carvalho J.S. da Gama Fischer A.Q.L. de Souza J.S. Viana S.R.S. Chalub A.D.L. de Souza M.G.C. Carvalho

Gastric cancer is one of most frequent causes of death in Brazil. The city of Manaus has one of the highest incidences of this disease in Brazil. The Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that is classified as a group 1 carcinogen by the International Agency for Research on Cancer. We obtained biopsies from 6 control subjects and 10 patients with gastric carcinomas living in Mana.. Read More»

Genet. Mol. Res. 11(4): 2012.October.15.3

DOI: 10.4238/2012.October.15.3

Bioinformatics   Review Article

Personalized diagnosis by cached solutions with hypertension as a study model

    P.C. Carvalho, S.S. Freitas, A.B. Lima, M. Barros, I. Bittencourt, W. Degrave, I. Cordovil, R. Fonseca, M.G.C. Carvalho, R.S. Moura Neto and P.H. Cabello

Statistical modeling of links between genetic profiles with environmental and clinical data to aid in medical diagnosis is a challenge. Here, we present a computational approach for rapidly selecting important clinical data to assist in medical decisions based on personalized genetic profiles. What could take hours or days of computing is available on-the-fly, makin.. Read More»

Genet. Mol. Res. 5(4):

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