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H.Q. Zhang

Publications of : H.Q. Zhang
Animal Genetics   Research Article

A comparative study on genetic characteristics of two new varieties of Pelodiscus sinensis and their hybrid

Chinese soft-shelled turtle Pelodiscus sinensis has been an important aquaculture species in Southeast Asian countries. To breed a new variety of soft-shelled turtle with excellent properties and to evaluate the effect of hybridization of two turtle strains with a highly different trait phenotype, inheritance, microsatellite loci, and transcriptome analysis were stu.. Read More»

Genet. Mol. Res. 16(3): gmr16039148

DOI: 10.4238/gmr16039148

Plant Genetics   Research Article

Differentiation of four strains of Chinese soft-shelled turtle (Pelodiscus sinensis) based on high-resolution melting analysis of single nucleotide polymorphism sites in mitochondrial DNA

    H.Q. Zhang, C. Zhang, X.J. Xu, J.J. Zhu, Z.Y. He and J.Z. Shao

The Chinese soft-shelled turtle (Pelodiscus sinensis) has been one of the most economically important aquatic animals in China for thousands of years, and several breeding strains have been formed. Since the morphological characteristics of some strains are similar, a rapid and accurate molecular method to differentiate between strains is required. In this study, partial sequences of mitochondr.. Read More»

Genet. Mol. Res. 14(4): 2015.October.26.10

DOI: 10.4238/2015.October.26.10

Medical Genetics   Research Article

Major quality trait analysis and QTL detection in hexaploid wheat in humid rain-fed agriculture

    H.M. Li, Z.X. Tang, H.Q. Zhang, B.J. Yan and Z.L. Ren

Humid rain-fed agriculture is a special environment for wheat (Triticum aestivum) culture that tends to negatively affect wheat yield and quality. To identify quality characters of wheat in a humid environment, we conducted quality analysis and quantitative trait loci (QTL) detection in a recombinant inbred line whose parent had a high level of quality for several years. We found that high-qual.. Read More»

Genet. Mol. Res. 12(2): 2013.May.21.5

DOI: 10.4238/2013.May.21.5

Plant Genetics   Research Article

Separation and identification of Musa acuminate Colla (banana) leaf proteins by two-dimensional gel electrophoresis and mass spectrometry

    Y. Lu, Y.X. Qi, H. Zhang, H.Q. Zhang, J.J. Pu and Y.X. Xie

To establish a proteomic reference map of Musa acuminate Colla (banana) leaf, we separated and identified leaf proteins using two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and mass spectrometry (MS). Tryptic digests of 44 spots were subjected to peptide mass fingerprinting (PMF) by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MS. Three spots that were no.. Read More»

Genet. Mol. Res. 12(4): 2013.December.19.6

DOI: 10.4238/2013.December.19.6

Medical Genetics   Research Article

miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression

    D.S. Wang, H.Q. Zhang, B. Zhang, Z.B. Yuan, Z.K. Yu, T. Yang, S.Q. Zhang, Y. Liu and X.X. Jia

Many studies have shown that microRNA (miR)-133 functions as a tumor suppressor in a variety of metastatic cancers, including breast cancer, gastric cancer, and liver fibrosis. However, the influence of miR-133 on pituitary tumor malignancy has not yet been reported. The purpose of this study was to explore the role of miR-133 in pituitary tumor cell migration and i.. Read More»

Genet. Mol. Res. 15(1): gmr.15017453

DOI: 10.4238/gmr.15017453

Human Genetics   Research Article

Interaction of six candidate genes in essential hypertension

    D.C. Hu, X.L. Zhao, J.C. Shao, W. Wang, J. Qian, A.H. Chen, H.Q. Zhang, H. Guo, J. Jiang and H.Y. Li

We explored the interaction of 6 candidate genetic mutations in essential hypertension (EH). The mutations AGT M235T, ACE I/D, eNOS Glu298Asp, ET-2 A985G, ANP T2238C, and NPRC A-55C were detected using a genechip microarray in 100 patients with EH and 97 controls from the Han population living in the Yunnan Province of China. Risks of EH were evaluated with respect to a combination of these gen.. Read More»

Genet. Mol. Res. 13(4): 2014.October.20.14

DOI: 10.4238/2014.October.20.14

Human Genetics   Research Article

Efficacy of dendritic cell-cytokine-induced killer immunotherapy plus intensity-modulated radiation therapy in treating elderly patients with esophageal carcinoma

    L. Yan, M. Wu, N. Ba, L.J. Wang, H.Q. Zhang, G.Y. Shi, Z.S. Zhang and X.J. Wang

We investigated the clinical efficacy of adoptive cytokine-induced killer (CIK) cell and dendritic cell (DC) therapy plus intensity-modulated radiation therapy (IMRT) for treating elderly patients with esophageal carcinoma (EC). In total, 68 elderly patients with EC were randomized to receive IMRT plus DC-CIK immunotherapy (study group, N = 34) or IMRT only (control group, N = 34). Clinical eff.. Read More»

Genet. Mol. Res. 14(1): 2015.February.2.13

DOI: 10.4238/2015.February.2.13

Medical Genetics   Research Article

Genomic identification, phylogeny, and expression analysis of MLO genes involved in susceptibility to powdery mildew in Fragaria vesca

    L.X. Miao, M. Jiang, Y.C. Zhang, X.F. Yang, H.Q. Zhang, Z.F. Zhang, Y.Z. Wang and G.H. Jiang

The MLO (powdery mildew locus O) gene family is important in resistance to powdery mildew (PM). In this study, all of the members of the MLO family were identified and analyzed in the strawberry (Fragaria vesca) genome. The strawberry contains at least 20 members of the MLO family, and the protein sequence contained between 171 and 1485 amino acids, with 0-34 introns. Chromosomal localization s.. Read More»

Genet. Mol. Res. 15(3): gmr.15038400

DOI: 10.4238/gmr.15038400

Human Genetics   Research Article

Lack of association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population

    J.J. Lu, H.Q. Zhang, P. Mai, X. Ma, X. Chen, Y.X. Yang and L.P. Zhang

We conducted a case-control study to assess the association between single nucleotide polymorphisms in the ERCC5 promoter (rs2094258 and rs751402) and development of gastric cancer in a Chinese population. This investigation included 184 patients with pathologically diagnosed gastric cancer and 206 healthy subjects recruited between October 2012 and December 2014. T.. Read More»

Genet. Mol. Res. 15(2): gmr.15027779

DOI: 10.4238/gmr.15027779