Microbial Genetics
Adaptability and stability of soybean genotypes in off-season cultivation
Authors: R.O. Batista, R.L. Hamawaki, L.B. Sousa, A.P.O. Nogueira and O.T. Hamawaki
The oil and protein contents of soybean grains are important quantitative traits for use in breeding. However, few breeding programs perform selection based on these traits in different environments. This study assessed the adaptability and stability of 14 elite early soybean breeding lines in off-season cultivation with respect to yield, and oil and prot.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.26
- DOI:
- 10.4238/2015.August.14.26
Characteristics of mature wheat embryos with different resistance to scab cultured in vitro with Fusarium graminearum crude toxin
Authors: S. Wang, M. Wang and C.Y. Zhang
Five wheat varieties with different resistance to scab were used to study the effect of Fusarium graminearum crude toxin on culture characteristics of mature wheat embryos in vitro. The results showed that the rate of induction and differentiation of mature embryo callus differed significantly between varieties, toxin concentration, and concentration x va.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.3
- DOI:
- 10.4238/2015.December.21.3
Investigation into the association between NLRP3 gene polymorphisms and susceptibility to type 2 diabetes mellitus
Authors: S. Wang, F. Fang, W.B. Jin, X. Wang and X.S. Zheng
We conducted a case-control study to investigate the role of three common polymorphisms (rs10754558, rs7512998, and rs12137901) of the gene NLR family, pyrin domain containing 3 (NLRP3) in the development of type 2 diabetes mellitus (T2DM). Between May 2013 and May 2014, 385 patients with T2DM and 401 control subjects were enrolled in our study. Genotypin.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.15
- DOI:
- 10.4238/2015.December.21.15
Silencing FKBP38 gene by siRNA induces activation of mTOR signaling in goat fetal fibroblasts
Authors: Y.T. Fu, X. Zheng, Q. He, X.Y. Jia, Z.X. Guo, R.Y. Yao, Y.F. Wang and Z.G. Wang
FKBP38 (also known as FKBP8) is a unique member of the FK506-binding protein (FKBP) family, and its role is controversial because it acts as an upstream regulator of the mTOR signaling pathway, which controls cell growth, proliferation, and differentiation. This study aimed to explore the role of FKBP38 in the activation of mTOR signaling in Cashmere goat.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.30
- DOI:
- 10.4238/2015.August.14.30
Treating congenital megacolon by transplanting GDNF and GFR�±-1 double genetically modified rat bone marrow mesenchymal stem cells
Authors: C.B. Zhou, C.H. Peng, W.B. Pang, D. Zhang and Y.J. Chen
We studied the survival and gene expression of glial cell line-derived neurotrophic factor (GDNF) and GDNF receptor a-1 (GFRa-1) double-genetically modified rat bone marrow mesenchymal stem cells (BMSCs) transplanted into the intestinal walls of the rat models with congenital megacolon and determine the feasibility of treatment by transplantation of doubl.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.8
- DOI:
- 10.4238/2015.August.14.8
Molecular and chemical characterization of vetiver, Chrysopogon zizanioides (L.) Roberty, germplasm
Authors: R.S. Celestino, M.I. Zucchi, J.B. Pinheiro, J.B. Campos, A.A. Pereira, F.G. Bianchini, R.N. Lima, M.F. Arrigoni-Blank, P.B. Alves and A.F. Blank
Due to the economic interests in vetiver, Chrysopogon zizanioides (L.) Roberty, molecular and chemical studies are essential to generate information for its sustainable exploitation. The aim of this study was to undertake a molecular and chemical characterization of vetiver accessions of the active germplasm bank of the Universidade Federal de Sergipe. Th.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.9
- DOI:
- 10.4238/2015.August.14.9
Overexpression of an endo-1,4-�²-glucanase V gene (EGV) from Trichoderma reesei leads to the accumulation of cellulase activity in transgenic rice
Authors: X.Y. Li, F. Liu, Y.F. Hu, M. Xia, B.J. Cheng, S.W. Zhu and Q. Ma
The ectopic expression of cellulase in biomass can reduce the cost of biofuel conversion. This trait modification technique is highly beneficial for biofuel production. In this study, we isolated an endo-1,4-beta-glucanase gene (EGV) from Trichoderma reesei and inserted this gene downstream of a fragment encoding the signal peptide Apo-SP in a modified pC.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.24
- DOI:
- 10.4238/2015.December.21.24
C/EBP�± gene as a genetic marker for beef quality improvement
Authors: C. Adoligbe, Y.F. Huangfu, L.S. Zan and H. Wang
Intramuscular fat (IMF) or intramuscular triglycerides are interspersed throughout the skeletal muscles. The IMF, also called marbling, imparts meat with flavor and juiciness and is one of the core criteria for judging carcass value. The quantity of IMF is influenced entirely by genetics. Recently, understanding the underlying genetic bases of IMF has bee.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.1
- DOI:
- 10.4238/2015.August.14.1
Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population
Authors: B. Zhang, C.Y. Gao, H.B. Zhang, B. Yang, J.F. Yin, S.G. Wei, Y.S. Zhu, X.N. Jia and S.B. Li
Previous studies have found that the vaccinia related kinase 2 gene (VRK2) polymorphism was associated with schizophrenia (SCZ) in the worldwide population. This association was further supported by VRK2 mRNA expression patterns and brain structure variations. Here, we analyzed four single nucleotide polymorphisms (SNPs) of the VRK2 gene in a total popula.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.4
- DOI:
- 10.4238/2015.August.14.4
In silico characterization of hypothetical proteins from Paracoccidioides lutzii
Authors: P.F.F. Silva, E. Novaes, M. Pereira, C.M.A. Soares, C.L. Borges and S.M. Salem-Izacc
Nearly 60% of Paracoccidioides lutzii genes encode products annotated as hypothetical or predicted proteins (HPs). In this study, we describe the global detection and functional inference of HPs, using computational methods based on sequence similarity, identification of targeting signals, presence of known protein domains, and use of the Gene Ontology fu.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.11
- DOI:
- 10.4238/2015.December.21.11