Microbial Genetics
Macrophage proinflammatory response to the titanium alloy equipment in dental implantation
Authors: X. Chen, H.S. Li, Y. Yin, Y. Feng and X.W. Tan
Titanium alloy and stainless steel (SS) had been widely used as dental implant materials because of their affinity with epithelial tissue and connective tissue, and good physical, chemical, biological, mechanical properties and processability. We compared the effects of titanium alloy and SS on macrophage cytokine expression as well as their biocompatibil.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.25
- DOI:
- 10.4238/2015.August.7.25
Polymorphisms in the bovine CIDEC gene are associated with body measurement traits and meat quality traits in Qinchuan cattle
Authors: C.G. Mei, L.S. Gui, C.Z. Fu, H.C. Wang, J.L. Wang, G. Cheng and L.S. Zan
Previous studies have shown that the cell death-inducing DFF45-like effector-C (CIDEC) gene is involved in lipid storage and energy metabolism, suggesting that it is a potential candidate gene that affects body measurement traits (BMTs) and meat quality traits (MQTs). The aim of this study was to identify polymorphisms of the bovine CIDEC gene and analyze.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.10
- DOI:
- 10.4238/2015.August.7.10
Local expression and role of BMP-2/4 in injured spinal cord
Authors: Z.S. Cui, P. Zhao, C.X. Jia, H.J. Liu, R. Qi, J.W. Cui, J.H. Cui, Q. Peng, B. Lin and Y.J. Rao
We investigated local changes in BMP-2/4 expression in rat spinal cords 1 week following injury to study the damage effects of BMP-2/4 in spinal cord injury (SCI). Sprague Dawley rats (45, 4 months old) were randomized into three groups comprising 15 rats each: a SHAM group, an SCI without noggin group (SCIO), and an SCI with noggin group (SCID). The SCIO.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.20
- DOI:
- 10.4238/2015.August.7.20
Effects of different anesthetic approaches on postoperative complications in HIV-infected patients
Authors: W.W. Zhang, Y.P. Wang, Y.Q. Wang, X.M. Ji and M.Y. Zhang
The aim of this study was to investigate the effects of three different methods of anesthesia on patients with human immunodeficiency virus (HIV) infection, which could lead to an improvement in postoperative outcomes in these patients. A total of 90 patients undergoing an operation while being treated for an HIV infection were included in this study. Pat.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.22
- DOI:
- 10.4238/2015.August.7.22
Associations of single nucleotide polymorphisms in the Pygo2 coding sequence with idiopathic oligospermia and azoospermia
Authors: S.-Q. Ge, J. Grifin, L.-H. Liu, K.I. Aston, L. Simon, T.G. Jenkins, B.R. Emery and D.T. Carrell
Male infertility is often associated with a decreased sperm count. The Pygo2 gene is expressed in the elongating spermatid during chromatin remodeling; thus impairment in PYGO2 function might lead to spermatogenic arrest, sperm count reduction, and subsequent infertility. The aim of this study was to identify mutations in Pygo2 that might lead to idiopath.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.14
- DOI:
- 10.4238/2015.August.7.14
Diadenylate cyclase evaluation of ssDacA (SSU98_1483) in Streptococcus suis serotype 2
Authors: B. Du and J.H. Sun
Cyclic diadenosine monophosphate is a recently identified signaling molecule. It has been shown to play important roles in bacterial pathogenesis. SSU98_1483 (ssDacA), which is an ortholog of Listeria monocytogenes DacA, is a putative diadenylate cyclase in Streptococcus suis serotype 2. In this study, we determined the enzymatic activity of ssDacA in vit.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.34
- DOI:
- 10.4238/2015.June.18.34
Development of novel polymorphic microsatellite markers for the blood clam Tegillarca granosa by pyrosequencing
Authors: Y.H. Dong, H.H. Yao, S.F. Shi, Y.B. Bao and Z.H. Lin
Large amounts of expressed sequence tags (ESTs) generated using next-generation sequencing technologies provide a cost-effective and valuable genomic resource for the development of microsatellite markers. In this study, we isolated 115 novel polymorphic microsatellite markers for the blood clam Tegillarca granosa from ESTs in 454 sequencing data. All the.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.6
- DOI:
- 10.4238/2015.August.7.6
Role of inflammatory responses in the pathogenesis of human cerebral aneurysm
Authors: X.J. Fan, H.D. Zhao, G. Yu, X.L. Zhong, H. Yao and Q.D. Yang
We aimed to detect expressional profiles of intracellular cell adhesion molecule-1 (ICAM-1), nuclear factor-kappa B (NF-κB), and monocyte chemoattractant protein-1 (MCP-1) in human cerebral aneurysm, in order to investigate the effect of chronic inflammation on the pathogenesis of cerebral aneurysm. Samples from 40 cases of human cerebral aneurysms .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.15
- DOI:
- 10.4238/2015.August.7.15
Association between 1p13.3 genomic markers and coronary artery disease: a meta-analysis involving patients and controls
Authors: J. Guo, Y.X. Luo, L.X. Tao1 and X.H. Guo
Recently, genome-wide association studies on cardiovascular disease identified a series of associated single nucleotide polymorphisms in an intergenic region of chromosome 1p13.3. We investigated the association of this locus with cardiovascular disease in 13 case-control studies and undertook a meta-analysis for effect size, heterogeneity, publ.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.18
- DOI:
- 10.4238/2015.August.7.18
Regulation of CD4+FOXP3+ T cells by CCL20/CCR6 axis in early unexplained recurrent miscarriage patients
Authors: X.X. Zhang, X.M. Kang and A.M. Zhao
Expression and function of CCR6/CCL20 in CD4+FOXP3+ regulatory T cells (Tregs) was investigated in unexplained recurrent miscarriage (URM) patients. Flow cytometry, reverse transcription-polymerase chain reaction, enzyme-linked immunosorbent assay, western blots, and Transwell migration assays were used to analyze the expression and function of regulatory.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.24
- DOI:
- 10.4238/2015.August.7.24