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Microbial Genetics

Microbial Genetics   Research Article

Microsatellite markers in Paulownia kawakamii (Scrophulariaceae) and cross-amplification in other Paulownia species

Authors: H.W. Wang, J.M. Duan, P. Zhang, Y.Q. Cheng, J.W. Wu and G.Z. Wang

Paulownia kawakamii is a fast-growing timber tree. In this study, 21 primer sets were developed using an enriched genomic library. The genetic diversity was measured in one P. kawakamii population. The number of alleles per locus ranged from 2 to 19. The observed and expected heterozygosities varied from 0.158 to 0.842 (mean = 0.421) and from 0.376 to 0.9.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.6
DOI:
10.4238/2013.September.19.6
Microbial Genetics   Research Article

Influences of species mixture on biomass of Masson pine (Pinus massoniana Lamb) forests

Authors: L.F. Zhang, Y.Y. Huang, L.P. Liu and S.L. Fu

The effect of tree diversity on productivity in subtropical forests in China is poorly understood. We investigated the biomasses of trees, understory vegetation, coarse roots, and fine roots with varying proportions of Pinus massoniana, mixed with other tree species in stands of the same age, to examine the effects of tree diversity. With an increase of P.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.5
DOI:
10.4238/2013.September.19.5
Microbial Genetics   Research Article

Bovine herpesvirus type 5 infection regulates Bax/BCL-2 ratio

Authors: A.F. Garcia, J.B. Novais, T.F. Antello, C. Silva-Frade, M.C. Ferrarezi, E.F. Flores and T.C. Cardoso

Bovine herpesvirus 5 (BoHV-5) is an α-herpesvirus that causes neurological disease in young cattle and is also occasionally involved in reproductive disorders. Although there have been many studies of the apoptotic pathways induced by viruses belonging to the family Herpesviridae, there is little information about the intrinsic programmed cell death.. Read More»

Genet. Mol. Res. 12(3):
2013.September.23.8
DOI:
10.4238/2013.September.23.8
Microbial Genetics   Research Article

Antigenotoxic, and anticytotoxic activities of an ethanolic extract of Lafoensia pacari (Lythraceae) stem bark in bacteria and mice

Authors: D.C.S. Lima, C.R. Silva, B.L. Sampaio, J.R. de Paula and L. Chen-Chen

Lafoensia pacari (Lythraceae), popularly known in Brazil as “pacari”, is a small tree native to the Cerrado that is used in folk medicine to treat cancer and as an anti-inflammatory and cicatrizing agent. We evaluated the genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of an ethanol extract of L. pacari stem bark (EESB) using.. Read More»

Genet. Mol. Res. 12(3):
2013.September.23.7
DOI:
10.4238/2013.September.23.7
Microbial Genetics   Research Article

An A/G polymorphism rs3746444 in miR-499 is associated with increased cancer risk: a meta-analysis

Authors: N. Wang, ZQ Tian, Y. Li, R.M. Zhou and G.Y. Wang

An A/G polymorphism (rs3746444) has been identified in the miR-499 gene that can change the conformation of the secondary gene structure and thereby directly affect binding to target mRNAs and the microRNA (miRNA) maturation process, thus altering protein expression and potentially contributing to cancer susceptibility. Numerous studies investigating the .. Read More»

Genet. Mol. Res. 12(3):
2013.September.23.14
DOI:
10.4238/2013.September.23.14
Microbial Genetics   Research Article

Molecular evolution and adaptation of the mitochondrial cytochrome b gene in the subgenus Martes

Authors: B. Li, B. Malyarchuk, X.B. He and M. Derenko

Martes species represent a typical example of rapid evolutionary radiation and a recent speciation event. To identify regions of the genome that experienced adaptive evolution, which might provide clues to their functional importance and may be informative about the features that make each species unique, we sought evidence of molecular adaptation in the .. Read More»

Genet. Mol. Res. 12(3):
2013.September.23.13
DOI:
10.4238/2013.September.23.13
Microbial Genetics   Research Article

Association of the G403A polymorphism in the RANTES gene with coronary artery disease: a meta-analysis

Authors: K. Cui, X.Y. Ge and H.L. Ma

The G403A polymorphism in the RANTES (regulated on activation normal T cell expressed and secreted) gene has a key role in the expression of RANTES, which has been detected in a range of cells in atherosclerotic plaque. However, the association of this polymorphism with the risk of coronary artery disease (CAD) remains controversial. A meta-analysis was p.. Read More»

Genet. Mol. Res. 12(3):
2013.September.23.10
DOI:
10.4238/2013.September.23.10
Microbial Genetics   Research Article

Conservation genetics of Annamocarya sinensis (Dode) Leroy, an endangered endemic species

Authors: Z.Y. Zhang, X.M. Pang, J.W. Han, Y. Wang and Y.Y. Li

The endangered perennial plant Annamocarya sinensis (Dode) Leroy is a tertiary relict tree restricted to southeastern China and northern Vietnam. To explore endangerment mechanisms, develop protection strategies, and guide reintroduction efforts for this species, we investigated genetic diversity and population structure by surveying 70 individuals from t.. Read More»

Genet. Mol. Res. 12(3):
2013.March.11.9
DOI:
10.4238/2013.March.11.9
Microbial Genetics   Research Article

Association between survivin gene promoter -31G/C and -644C/T polymorphisms and non-small cell lung cancer

Authors: E. Aynaci, E. Coskunpinar, A. Eren, O. Kum, Y.M. Oltulu, N. Akkaya, A. Turna, I. Yaylim and P. Yildiz

Lung cancer is the most common cancer worldwide. Survivin is one of the first reported inhibitors of apoptosis proteins, which is an important family of proteins that regulate apoptosis. The survivin gene is located on human chromosome 17q25, which is composed of 142 amino acids. A common polymorphism of the survivin gene promoter -31G/C has been shown to.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.9
DOI:
10.4238/2013.February.28.9
Microbial Genetics   Research Article

Influence of the 48867A>C (Asp358Ala) IL6R polymorphism on response to a lifestyle modification intervention in individuals with metabolic syndrome

Authors: V.R.A. Vargas, S.L. Bonatto, F.E. Macagnan, A.M.P. Feoli, C.S. Alho, N.D.V. Santos and V.M. Schmitt

We evaluated the response of individuals with metabolic syndrome to lifestyle modification intervention and examined the influence of the 48867A>C (Asp358Ala) IL6R (rs2228145) polymorphism on this response. Participants were randomly divided into two groups: NI, nutritional intervention; NIE, nutritional intervention and exercise practice. Intervention.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.8
DOI:
10.4238/2013.February.28.8