Microbial Genetics

KIR gene polymorphism study in the Uygur population in Xinjiang, China

Authors: G.-Y. Lin and Y.-B. Wang

We analyzed killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and genotype and haplotype characteristics in the Uygur population, a non-nomadic ethnic group found in Xinjiang, China, to provide a basis for studies on relationships between KIRs and diseases in this group. Sequence-specific primer PCR was used to detect the KIR gene in 84 Uy.. Read More»

Genet. Mol. Res. 13(1):

http://dx.doi.org/2014.March.17.9

DOI:

http://dx.doi.org/10.4238/2014.March.17.9

From unicellularity to multicellularity - molecular speculations about early animal evolution

Authors: H.F. Hoenigsberg, M.H. T�­jaro and C. Sanabria

A morphological, physiological, developmental, and genetic organization of great complexity ineluctably unfolded from relatively simple phenomena invested with enormous potential. Sometime long ago in the Protererozoic times, parasitic invasions caused lower evolutionary levels to integrate into higher-level selection. Therefore, we have a multi-level sel.. Read More»

Genet. Mol. Res. 7(1):

vol7-1gmr375

DOI:

10.4238/vol7-1gmr375

On the absence of mutations in nucleotide excision repair genes in sporadic solid tumors

Authors: J.C.M. Mombach, M.A.A. Castro, J.C.F. Moreira and R.M.C. de Almeida

In general, stochastic tumors show genomic instability associated with the proliferation of DNA point mutations, that is, a mutator phenotype. This feature cannot be explained by a dysfunctional mismatch repair alone, and indicates that nucleotide excision repair (NER) and/or base excision repair should be suppressed. However, mutations in NER genes are n.. Read More»

Genet. Mol. Res. 7(1):

vol7-1gmr393

DOI:

10.4238/vol7-1gmr393

DNA repair by polymerase �´ in Saccharomyces cerevisiae is not controlled by the proliferating cell nuclear antigen-like Rad17/Mec3/Ddc1 complex

Authors: J.M. Cardone, M. Brendel and J.A.P. Henriques

DNA damage activates several mechanisms such as DNA repair and cell cycle checkpoints. The Saccharomyces cerevisiae heterotrimeric checkpoint clamp consisting of the Rad17, Mec3 and Ddc1 subunits is an early response factor to DNA damage and activates checkpoints. This complex is structurally similar to the proliferating cell nuclear antigen (PCNA), which.. Read More»

Genet. Mol. Res. 7(1):

vol7-1gmr405

DOI:

10.4238/vol7-1gmr405

Detection by denaturing gradient gel electrophoresis of ammonia-oxidizing bacteria in microcosms of crude oil-contaminated mangrove sediments

Authors: A.C.F. dos Santos, E.L.S. Marques, E. Gross, S.S. Souza, J.C.T. Dias, M. Brendel and R.P. Rezende

Currently, the effect of crude oil on ammonia-oxidizing bacterium communities from mangrove sediments is little understood. We studied the diversity of ammonia-oxidizing bacteria in mangrove microcosm experiments using mangrove sediments contaminated with 0.1, 0.5, 1, 2, and 5% crude oil as well as non-contaminated control and.. Read More»

Genet. Mol. Res. 11(1):

http://dx.doi.org/2012.January.27.6

DOI:

http://dx.doi.org/10.4238/2012.January.27.6

Molecular variability in Brycon cf. pesu M�¼ller and Troschel, 1845 (Characiformes: Characidae) from the Araguaia-Tocantins basin

Authors: R.S. Panarari-Antunes, A.J. Prioli, S.M.A.P. Prioli, H.F. J�ºlio Jr. C.S. Agostinho and L.M. Prioli

Brycon pesu is a small-sized fish distributed throughout the Amazon and Orinoco Basins and other coastal basins of northeastern South America. Brycon cf. pesu specimens from the Araguaia-Tocantins Basin are currently separated into two morphotypes, Brycon sp1 and Brycon sp2, owing to different coloration of their anal fin. Brycon sp2 has a reddish margin .. Read More»

Genet. Mol. Res. 7(1):

vol7-1gmr365

DOI:

10.4238/vol7-1gmr365

A simple boiling-based DNA extraction for RAPD profiling of landfarm soil to provide representative metagenomic content

Authors: J.H. Amorim, R.O. Vidal, G.V. Lacerda-Junior, J.C.T. Dias, M. Brendel, R.P. Rezende and J.C.M. Cascardo

Landfarm soils are employed in industrial and petrochemical residue bioremediation. This process induces selective pressure directed towards microorganisms capable of degrading toxic compounds. Detailed description of taxa in these environments is difficult due to a lack of knowledge of culture conditions required for unknown .. Read More»

Genet. Mol. Res. 11(1):

http://dx.doi.org/2012.January.27.5

DOI:

http://dx.doi.org/10.4238/2012.January.27.5

Contribution to the study of molecular defects of hemoglobin in the Brazilian population

Authors: Paula Juliana Antoniazzo Zamaro

The hemoglobinopathies belong to a diverse group of inherited disorders characterized by the reduced synthesis of one or more globin chains (thalassemia) or the synthesis of a structurally abnormal hemoglobin (Hb). Approximately 900 different hemoglobin variants characterized by mutations involving alpha, beta, gamma, and delta globin chains have been des.. Read More»

Genet. Mol. Res. 7(1):

vol7-1ta012

DOI:

10.4238/vol7-1ta012

Improved thermostable �±-amylase activity of Bacillus amyloliquefaciens by low-energy ion implantation

Authors: X.Y. Li, J.L. Zhang and S.W. Zhu

Thermostable α-amylase is of great importance in the starch fermentation industry; it is extensively used in the manufacture of beverages, baby foods, medicines, and pharmaceuticals. Bacillus amyloliquefaciens produces thermostable α-amylase; however, production of thermostable α-amylase is limited. Ion-beam .. Read More»

Genet. Mol. Res. 10(3):

vol10-3gmr1081

DOI:

10.4238/vol10-3gmr1081

Preliminary study regarding microbial diversity in landfarm soil by PCR-DGGE and prospection of surfactant and dibenzothiophene degradation activities

Authors: R.A. Nink

Genet. Mol. Res. 11(1):

http://dx.doi.org/2012.February.10.1

DOI:

http://dx.doi.org/10.4238/2012.February.10.1