Microbial Genetics
Meta-analysis of angiotensin-converting enzyme insertion/deletion polymorphism and myocardial infarction in Han Chinese
Authors: W. Zhao, S.T. Ma and L.Q. Cui
It has been suggested that the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism is linked to susceptibility to myocardial infarction (MI). In this study, we performed a meta-analysis to assess the relationship between ACE I/D polymorphism and MI in the Chinese Han population. Eight studies including a total of 1609 subjects w.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.15
- DOI:
- 10.4238/2015.July.17.15
Conservation of glycolytic oscillations in Saccharomyces cerevisiae and human pancreatic �²-cells: a study of metabolic robustness
Authors: A.S. Silva and J.A. Yunes
The present study compares two computer models of the first part of glucose catabolism in different organisms in search of evolutionarily conserved characteristics of the glycolysis cycle and proposes the main parameters that define the stable steady-state or oscillatory behavior of the glycolytic system. It is suggested that .. Read More»
- Genet. Mol. Res. 5(3):
Comparative analyses of the structure of the 1,3-�²-glucan synthase gene in Paracoccidioides brasiliensis isolates
Authors: H.T.S. Okamoto, C.M.A. Soares and M. Pereira
The evolutionary origin and significance of spliceosomal introns have been the subject of many investigations. Two theories, “introns- early” theory and “introns-late” theory, have been proposed to explain the evolution of introns in eukaryotic genes. Intron position is generally conserved in paralogue .. Read More»
- Genet. Mol. Res. 5(2):
Moquiniastrum polymorphum subsp floccosum extract: screening for mutagenic and antimutagenic activity
Authors: R.J. Oliveira, N. de David, J.R. Pesarini, T.D. Nogueira, C.A.L. Kassuya, R.L.B. Strapasson, M.E.A. Stefanello, A.C.D. Monreal, R. Matuo and A.C.M.B. Antoniolli-Silva
Moquiniastrum polymorphum subsp floccosum (Cabrera) G. Sancho is used in traditional Brazilian medicine to treat inflammation and infection, which is supported by scientific data. However, only one study has been conducted on the mutagenic activity of the extract, which has important safety implications. This study evaluated t.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048976
- DOI:
- 10.4238/gmr15048976
Increase in mitochondrial DNA quantity and impairment of oxidative phosphorylation in bovine fibroblast cells treated with ethidium bromide for 15 passages in culture
Authors: Marcos Roberto Chiaratti and Fl�¡vio Vieira Meirelles
Bovine fetal fibroblast cells were treated with ethidium bromide at a low concentration for 15 passages in culture to determine its effect on mitochondrial DNA copy number and on cell metabolism. Mitochondrial membrane potential and lactate production were estimated in order to characterize cell metabolism. In addition, mitoch.. Read More»
- Genet. Mol. Res. 5(1):
GenoMycDB: a database for comparative analysis of mycobacterial genes and genomes
Authors: Marcos Catanho, Daniel Mascarenhas, Wim Degrave and Antonio BasÃ?Âlio de Miranda
Several databases and computational tools have been created with the aim of organizing, integrating and analyzing the wealth of information generated by large-scale sequencing projects of mycobacterial genomes and those of other organisms. However, with very few exceptions, these databases and tools do not allow for massive an.. Read More»
- Genet. Mol. Res. 5(1):
Investigating genetic diversity in sapucaia using inter simple sequence repeat markers
Authors: R.C. Borges, F.M.G. Santos, M.C.C. Maia, P.S.C. Lima and S.E.S. Valente
Sapucaia is a tree species originating from the Brazilian Amazon and is widely distributed in Brazil, especially in the mid-north region (Piauí and Maranhão states). Its seeds are rich in calories and proteins, and possess great potential for commercialization. Little is known about the genetic variability in the germplasm of most Lecythis s.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038565
- DOI:
- 10.4238/gmr.15038565
Characterization and molecular epidemiology of extensively prevalent nosocomial isolates of drug-resistant Acinetobacter spp
Authors: A.A. Carvalho, L.L. Cardoso, H.S. Nogueira, E.V. Menezes, M.A.S. Xavier, N.A.P. Barreto, L.F. Fernandes and A.R.E.O. Xavier
Acinetobacter sp isolates deserve special attention once they have emerged globally in healthcare institutions because they display numerous intrinsic and acquired drug-resistance mechanisms. This study assessed the antibiotic susceptibility profile, the presenceof the genetic marker blaOXA-23, and the clonal relationship among 34 nosocomial isolates of A.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038608
- DOI:
- 10.4238/gmr.15038608
Rhizosphere bacteriome of the medicinal plant Sapindus saponaria L. revealed by pyrosequencing
Authors: A. Garcia, J.C. Polonio, A.D. Polli, C.M. Santos, S.A. Rhoden, M.C. Quecine, J.L. Azevedo and J.A. Pamphile
Sapindus saponaria L. of Sapindaceae family is popularly known as soldier soap and is found in Central and South America. A study of such medicinal plants might reveal a more complex diversity of microorganisms as compared to non-medicinal plants, considering their metabolic potential and the chemical communication between the.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049020
- DOI:
- 10.4238/gmr15049020
Response of Malpighia emarginata active germplasm bank accessions to Meloidogyne enterolobii parasitism
Authors: A.A. Moreira, L.S.S. Martins, R.S. Musser, R.M. Moraes Filho, W.A. Maranh�£o, J.G.A. Rossiter and A.V.V. Montarroyos
Malpighia emarginata is cultivated in almost all Brazil and is considered an important agricultural crop. The root-knot nematode Meloidogyne enterolobii has been described as a major threat to this crop, causing great production losses. Due to the scarcity of information about the severity of this parasite in M. emarginata pla.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048868
- DOI:
- 10.4238/gmr15048868