Microbial Genetics
Cloning, molecular characterization, and expression analysis of a nucleoporin gene (rgNUP98-96) from Rehmannia glutinosa
Authors: Y.H. Yang and M.J. Li
Nucleoporin 98 (NUP98) and nucleoporin 96 (NUP96) are essential components of the nuclear pore complex (NPC) in eukaryote cells. However, there is a lack of available information about complete Rehmannia glutinosa NUP98-96 (rgNUP98-96) sequences. Here, the full-length cDNA sequence of rgNUP96-98 was isolated from R. glutinosa using rapid amplification of .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.23
- DOI:
- 10.4238/2015.October.21.23
Association between the interleukin-6 -174 G/C polymorphism and risk of ischemic stroke: a meta-analysis
Authors: X.F. Jin, D.L. Wang2, Y. Zhou and H. Xiong
Numerous studies have evaluated the association between the -174 G/C polymorphism in the interleukin-6 (IL6) gene and ischemic stroke risk. However, the results have been inconsistent. In this study, we performed a meta-analysis to assess the association of the IL6 -174 G/C polymorphism with ischemic stroke. Published literatures from PubMed and Embase da.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.3
- DOI:
- 10.4238/2015.October.26.3
Analysis of upland cotton (Gossypium hirsutum) response to Verticillium dahliae inoculation by transcriptome sequencing
Authors: B.X. Shao, Y.L. Zhao, W. Chen, H.M. Wang, Z.J. Guo, H.Y. Gong, X.H. Sang, Y.L. Cui and C.H. Wang
Verticillium wilt is one of the main diseases in cotton (Gossypium hirsutum), severely reduces yield and fiber quality, and is difficult to be controlled effectively. At present, the molecular mechanism that confers resistance to this disease is unclear. Transcriptome sequencing is an important method to detect resistance genes, explore metabolic pathways.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.8
- DOI:
- 10.4238/2015.October.26.8
Biological activity of cytotoxic dendritic cells cocultured with cytokine-induced killer cells and their effect on acute leukemia cells
Authors: X.Y. Cheng and J.L. Li
We cocultured cytokine-induced killer (CIK) cells with dendritic cells (DCs) in vitro and investigated their proliferation, immunophenotype changes, secretory cytokine levels, and their antitumor effects on acute myeloid leukemia (AML) cells. DCs and CIK cells were acquired from healthy human peripheral blood mononuclear cells and cocultured as an experim.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.17
- DOI:
- 10.4238/2015.October.26.17
Characterization and expression analysis of a cyclin B gene from black tiger shrimp (Penaeus monodon)
Authors: C. Zhao, M.J. Fu, F.L. Zhou, Q.B. Yang, S.G. Jiang and L.H. Qiu
The open reading frame of black tiger shrimp (Penaeus monodon) cyclin B (Pmcyclin B) was identified, based on cDNA sequence registered in GenBank (accession No. EF015590). The target sequence was 1206 bp, corresponding to 401 amino acids. Two conserved signature sequences of the cyclin B gene family were found in the Pmcyclin B deduced aa sequence. Tempor.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.36
- DOI:
- 10.4238/2015.October.26.36
A novel lumazine synthase molecule from Brucella significantly promotes the immune-stimulation effects of antigenic protein
Authors: Z.Q. Du and J.Y. Wang
Brucella, an intracellular parasite that infects some livestock and humans, can damage or destroy the reproductive system of livestock. The syndrome is referred to as brucellosis and often occurs in pastoral areas; it is contagious from livestock to humans. In this study, the intact Brucella suis outer membrane protein 31 (omp31) gene was cloned, recombin.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.4
- DOI:
- 10.4238/2015.October.26.4
MicroRNA expression profile of a Malaysian Bajau family with familial mitochondrial neurogastrointestinal encephalomyopathy
Authors: F.L. Yong, C.W. Wang and K.S. Tan
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare, autosomal recessive disorder associated with mutations in the thymidine phosphorylase (TYMP) gene. The main objective of this study was to characterize the genetic profiles of the deceased proband’s family members (N = 4) using DNA sequencing and to determine miRNA deregulation.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.13
- DOI:
- 10.4238/2015.October.26.13
Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis
Authors: C.C. Guo, W.H. Huang, N. Zhang, F. Dong, L.P. Jing, Y. Liu, X.G. Ye, D. Xiao, M.L. Ou, B.H. Zhang, M. Wang, W.K. Liang, G. Yang and C.X. Jing
Celiac disease (CD) is a common autoimmune disorder characterized by heightened immunological response to ingested gluten. Certain gene polymorphisms of IL2/IL21 (rs6822844 and rs6840978) and SH2B3 (rs3184504) may influence susceptibility to CD, although the effects remain unclear. We performed a meta-analysis of the associations between rs6822844, rs6840.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.19
- DOI:
- 10.4238/2015.October.26.19
Immunohistochemical localization of sex hormone receptors in two Raillietina tapeworms
Authors: L. Chen, Y.M. Sun, L. Mu, Y. Zeng, H.Y. Li and T.H. Yang
Sex hormone receptors play critical roles in development and reproduction. However, it is not known whether they exist in Raillietina tapeworms, and if they do, whether they have a similar function to that in vertebrates. We examined the immunohistochemical distributions of androgen receptors (ARs), estrogen receptors (ERs), a.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019033
- DOI:
- 10.4238/gmr16019033
Comparative fusion expression of maize SINAT5 in two different strains of Escherichia coli
Authors: A. Gholizadeh
SINAT5 is a plant E3 ligase that regulates auxin signaling and root morphogenesis by ubiquitination of the NAC1 protein. Consequently, it may be a putative regulator of aspects of plant development cycles that are controlled by auxin. Efficient production, purification and correctly folded form of this protein are important requirements for functional stu.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.24.1
- DOI:
- 10.4238/2012.August.24.1