Medical Genetics
Blue-white screening liquid can eliminate false positives in blue-white colony screening
Authors: Y.S. Zhang
Although blue-white screening based on α-complementation has been widely used in the screening of genetically modified bacteria, only a single blue-white screening is typically not enough to eliminate false positives. Sometimes, a secondary blue-white screening for the target colonies is required. In this study, two meth.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027925
- DOI:
- 10.4238/gmr.15027925
Association between single nucleotide polymorphisms of X-ray repair cross-complementing protein 4 gene and development of pancreatic cancer
Authors: Y. Ding and L.N. Li
We performed a study to evaluate X-ray repair cross-complementing protein 4 (XRCC4) gene polymorphisms and the development of pancreatic cancer. A case-control study including 206 patients with newly diagnosed primary pancreatic cancer and 412 controls was performed between January 2011 and October 2013 in a Chinese population. Genotypes of XRCC4 rs180537.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.25
- DOI:
- 10.4238/2015.August.14.25
Human kallikrein 5 as a novel prognostic biomarker for triple-negative breast cancer: tissue expression analysis and relationship with disease course
Authors: F. Yang, J.Y. Li, Q.N. Yin, K. Yang, S.N. Dong, L.J. Bai, P. Liu and X.W. Tong
The purposes of this study were to analyze the expression and distribution of human kallikrein 5 (hK5) in triple-negative breast cancer (TNBC) tissues, to establish a standard operating procedure (SOP) for its immunohistochemical assay, and to evaluate the possibility of hK5 being a prognostic biomarker for TNBC. Recombinant hK5 protein and specific antib.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.14.28
- DOI:
- 10.4238/2015.August.14.28
Analysis of the genetic diversity of beach plums by simple sequence repeat markers
Authors: X.M. Wang, W.L. Wu, C.H. Zhang, Y.P. Zhang, W.L. Li and T. Huang
The purpose of this study was to measure the genetic diversity of wild beach plum and cultivated species, and to determine the species relationships using SSRs markers. An analysis of genetic diversity from ten beach plum germplasms was carried out using 11 simple sequence repeat (SSR) primers selected from 35 primers to generate distinct PCR products. Fr.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.2
- DOI:
- 10.4238/2015.August.19.2
Expression of genes coding for selected amino acid transporters in small intestine, liver, and skeletal muscle of pigs fed excess branched-chain amino acids
Authors: M. Cervantes, N. Arce, H. Garc�?a, M. Cota, J.K. Htoo and A. Morales
Excess Leu reduces the availability of Ile and Val in pigs likely by reducing absorption of the latter amino acids (AA). Twenty-four crossbred pigs were used to evaluate the effect of excess Leu alone or with surplus Ile and Val on the expression of cationic (b0,+AT and CAT1) and neutral (B0AT1) AA transporters in the small intestine, liver, and skeletal .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.11
- DOI:
- 10.4238/2015.August.19.11
Comments on the article ��?Relative h-index to compare the scientific performance of researchers� by L.A.S. Dias
Authors: L. Egghe
The relative h-index, proposed by L.A.S. Dias, is not useful to compare the scientific performance of researchers. This is shown by examples. More adequate alternatives include the g-index and the R-index... Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.13.8
- DOI:
- 10.4238/2013.June.13.8
Effect of parasitism of Diatraea saccharalis (Lepidoptera: Crambidae) larvae by the wasp Cotesia flavipes (Hymenoptera: Braconidae) in defense reactions against abiotic agents: production and encapsulation reaction
Authors: C.C.C. Nunes and T.L. Silva
This study aimed to determine prophenoloxidase (proPO) activation and nitric oxide (NO) production in the hemolymph of Diatraea saccharalis larvae non-parasitized and parasitized by the wasp Cotesia flavipes and/or inoculated with abiotic agent (Sephadex beads), during parasitism/inoculation, and related to larval age; the ultrastructure of the capsule fo.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.13.7
- DOI:
- 10.4238/2013.June.13.7
Impact of early enteral and parenteral nutrition on prealbumin and high-sensitivity C-reactive protein after gastric surgery
Authors: B. Li, H.-Y. Liu, S.-H. Guo, P. Sun, F.-M. Gong and B.-Q. Jia
We investigated the impact of early enteral nutrition (EEN) and parenteral nutrition (PN) on prealbumin (PA) and highsensitivity C-reactive protein (hs-CRP) in patients after gastric cancer surgery. Sixty-eight selected patients undergoing gastric cancer surgery were randomly divided into the EEN (N = 34) and PN (N = 34) groups. Body weight (BW), serum al.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.6
- DOI:
- 10.4238/2015.June.29.6
Impact of early postoperative enteral nutrition on clinical outcomes in patients with gastric cancer
Authors: B. Li, H.Y. Liu, S.H. Guo, P. Sun, F.M. Gong and B.Q. Jia
The impact of early enteral nutrition (EEN) on clinical outcomes of gastric cancer patients was investigated. Three hundred patients undergoing gastric cancer surgery from July 2010 to May 2014 were randomly divided into experimental and control groups (n = 150/ group). Experimental group patients received enteral nutrition in water during the early posto.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.7
- DOI:
- 10.4238/2015.June.29.7
Analysis of postoperative PSA changes after ultrasound-guided permanent [125I] seed implantation for the treatment of prostate cancer
Authors: X.L. Bian, C.Z. Wang, Y. Wang, Y.N. Li, L.Z. Zhang and L. Liu
The aim of this study was to explore postoperative changes in prostate-specific antigen (PSA) levels and risk factors that influence the clinical effects of ultrasound-guided permanent [125I] seed implantation in the treatment of prostate cancer. From July 2009 to December 2012, 41 prostate cancer patients who underwent transrectal ultrasound-guided [ 125.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.8
- DOI:
- 10.4238/2015.June.29.8