Human Genetics
Meta-analysis of epidemiological studies demonstrates significant association of PTGS2 polymorphism rs689470 and no significant association of rs20417 with prostate cancer
Authors: H.-T. Zhang, Y. Xu, Z.-H. Zhang and L. Li
Evidence is accumulating that chronic inflammation has an important role in prostate cancer. Two common polymorphisms in the prostaglandin-endoperoxide synthase 2 (PTGS2) gene, rs20417 and rs689470, have been found to alter the risk for prostate cancer, but the various studies are not in agreement. To derive a more precise est.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.13
- DOI:
- 10.4238/2012.June.15.13
Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population
Authors: S.G. Liu, L. Ma, Q.H. Cen, J.S. Huang, J.X. Zhang and J.J. Zhang
Genome-wide association studies in several ethnic groups have reported that polymorphisms of the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, located on 5p15.33, are associated with susceptibility to lung cancer. However, whether genetic variants of TERT-CLPTM1L are associated with an increased ris.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.4
- DOI:
- 10.4238/2015.May.4.4
Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer
Authors: M.S. Monteiro, D.B. Vilas Boas, C.B. Gigliotti and D.M.F. Salvadori
Endometriosis is a complex disease that has both benign and malignant characteristics. It affects 5-10% of women of reproductive age. Studies have demonstrated the existence of common genetic changes in endometriosis and ovarian cancer, suggesting a possible association between these 2 diseases. However, the mechanisms that le.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.28.9
- DOI:
- 10.4238/2014.January.28.9
RETRACTION of "ZNF797 plays an oncogenic role in gastric cancer"
Authors: D. Momenzadeh, S. Rahman Zadeh, M. Rezaei-Tavirani, A. Baradaran-Rafii, F. Ghasemvand and S. Heidari-Keshel
The article “ZNF797 plays an oncogenic role in gastric cancer” by D. Momenzadeh, S. Rahman Zadeh, M. Rezaei-Tavirani, A. Baradaran-Rafii, F. Ghasemvand and S. Heidari-Keshel published in Genetics and Molecular Research vol. 13 (4), pp. 8421-8427 in 2014, DOI: http://dx.doi.org/10.4238/2014.October.20.18, has been found to be substantially equa.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.2retraction
- DOI:
- 10.4238/2015.February.2.2retraction
Structural chromosomal abnormalities in couples in cases of recurrent spontaneous abortions in Jilin Province, China
Authors: H.-T. Fan, M. Zhang, P. Zhan, X. Yang, W.-J. Tian and R.-W. Li
Recurrent spontaneous abortions (RSAs) occur in approximately 15 to 20% of all clinically recognizable pregnancies. Structural chromosome abnormalities result in increased risk of pregnancy loss. Parental chromosomal abnormalities are an important genetic cause of RSAs. Some cytogenetic investigations have been performed in various countries and regions t.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017443
- DOI:
- 10.4238/gmr.15017443
RETRACTION of "Absolute quantification of free tumor cells in the peripheral blood of gastric cancer patients"
Authors: N. Bayat, M.M. Mokhtari, M. Rezaei-Tavirani, A. Baradaran-Rafii, S. Rahman Zadeh, S. Heidari-Keshel and F. Ghasemvand
The article â??Absolute quantification of free tumor cells in the peripheral blood of gastric cancer patientsâ? by N. Bayat, M.M. Mokhtari, M. Rezaei-Tavirani, A. Baradaran-Rafii, S. Rahman Zadeh, S. Heidari-Keshel and F. Ghasemvand published in Genetics and Molecular Research vol. 13 (2), pp. 4425-4432 in 2014, DOI: http://dx.doi.org/10.4238/2014.Jun.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.2retraction
- DOI:
- 10.4238/2015.February.2.2retraction
Genet. Mol. Res. 3 (2): 264-272 (2004) Standardization of conditions for the metabolic activation of N-nitrosodiethylamine in mutagenicity tests
Authors: Cl?¡udia Alessandra Fortes Aiub Luis Felipe Ribeiro Pinto Israel Felzenszwalb
-.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2correction0080
- DOI:
- 10.4238/vol8-2correction0080
Expression of EpCAM and Wnt/ ?²-catenin in human colon cancer
Authors: F.Q. Zhou, Y.M. Qi, H. Xu, Q.Y. Wang, X.S. Gao and H.G. Guo
The aims of this study were to explore the correlation between the expression of EpCAM and the Wnt/β-catenin pathway in human colon cancer and its clinical significance for the evaluation of cancer prognosis. Samples from colon cancer, para-carcinoma, or benign intestinal tissue from individual patients (50) and from normal intestinal mucosal tissues.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.6
- DOI:
- 10.4238/2015.May.4.6
Analysis of prognostic factors for infantile rotavirus infection
Authors: R. Zhou, J.L. Xu, D. Wu and J.L. Tang
In this study, we investigated the prognostic factors of infantile rotavirus (RV) infection. A total of 102 infants with RV enteritis were divided into 2 groups according to the standards of improvement and cure at the time of discharge from the hospital: improvement group (N = 58; 47 males and 11 females with an average age of 15.19 ± 5.03 months).. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.3
- DOI:
- 10.4238/2015.February.2.3
Lack of association of CYP1A1-MspI SNP and GSTM1 null genotypes with cancer in a Brazilian family with unusually high cancer incidence
Authors: L.N. Moraes, M.F. Borges, P.A.C. Sousa, P.C. Venere and I.L. Souza
Research has shown that genetic polymorphisms in biotransformation enzymes, such as CYP1A1 and GSTM1, are related to a greater or lesser susceptibility to various cancers. We made an analysis of CYP1A1m1 SNP and GSTM1 null genotypes in a family group (71 members) related by consanguinity who had an unusually high incidence of .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.10
- DOI:
- 10.4238/2012.June.15.10