Human Genetics
Expression and clinical significance of CD4+ CD45+ peripheral blood T cells in patients with ulcerative colitis
Authors: L.Y. Guo, Y.R. Li and X.P. Jin
The objectives of this study were to explore the expression of peripheral blood CD4+CD45+ T cells in patients with ulcerative colitis (UC) and determine its clinical value. We selected 80 patients with UC from the First Affiliated Hospital of Liaoning Medical University from March 2012 to December 2013. Of these, 27 had mildly active, 28 moderately active.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.August.28.20
- DOI:
- http://dx.doi.org/10.4238/2015.August.28.20
Genetic diversity of yacon accessions using ISSR markers
Authors: R.M. Lorenzoni, F. Menine, E. Marques J�ºnior, F.L. Oliveira and T.C.B. Soares
Yacon cultivation has been intensified and the investigations of this crop have increased at the scientific, agricultural, and social levels because the roots of yacon show beneficial properties for human health, such as reducing cholesterol and glucose blood levels. Since the investigations involving yacon are very recent, th.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029576
- DOI:
- 10.4238/gmr16029576
Selection of morphoagronomic descriptors for the characterization of accessions of cassava of the Eastern Brazilian Amazon
Authors: R.S. Silva, E.F. Moura, J.T. Farias-Neto, C.A.S. Ledo and J.E. Sampaio
The aim of this study was to select morphoagronomic descriptors to characterize cassava accessions representative of Eastern Brazilian Amazonia. It was characterized 262 accessions using 21 qualitative descriptors. The multiple-correspondence analysis (MCA) technique was applied using the criteria: contribution of the descript.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029595
- DOI:
- 10.4238/gmr16029595
Biotools: an R function to predict spatial gene diversity via an individual-based approach
Authors: A.R. da Silva, G. Malafaia and I.P.P. Menezes
The gene diversity or expected heterozygosity (HE) is based on the allele frequency and is often used as a measure of genetic variability of populations. Knowing the pattern of spatial distribution of HE can be useful for determining strategies of conservation and sampling of collections of individuals. In addition, it can all.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029655
- DOI:
- 10.4238/gmr16029655
Roles of the AIB1 protein in the proliferation and transformation of human esophageal squamous cell carcinoma
Authors: L. Li, P. Wei, M.-H. Zhang, W. Zhang, Y. Ma, X. Fang, C.-L. Hao and Z.-H. Zhang
The aim of this study was to investigate the expression of AIB1 in human esophageal squamous cell carcinoma and its correlation with Ki67 expression. The immunohistochemical method streptavidin-perosidase was used to analyze the expression of AIB1 and Ki67 in specimens from 60 patients with esophageal squamous cell carcinoma and in 20 control individuals .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.4
Molecular analysis of genetic diversity among vine accessions using DNA markers
Authors: A.F. da Costa, P.E. Teodoro, L.L. Bhering, F.D. Tardin, R.F. Daher, W.F. Campos, A.P. Viana and M.G. Pereira
Viticulture presents a number of economic and social advantages, such as increasing employment levels and fixing the labor force in rural areas. With the aim of initiating a program of genetic improvement in grapevine from the State University of the state of Rio de Janeiro North Darcy Ribeiro, genetic diversity between 40 gen.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029586
- DOI:
- 10.4238/gmr16029586
The G1138A mutation rate in the fibroblast growth factor receptor 3 (FGFR3) gene is increased in cells carrying the t (4; 14) translocation
Authors: P.L. Reddy and R.P. Grewal
Spontaneous mutations are a common phenomenon, occurring in both germ-line and somatic genomes. They may have deleterious consequences including the development of genetic disorders or, when occurring in somatic tissues, may participate in the process of carcinogenesis. Similar to many mutational hotspots, the G1138A mutation .. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2gmr564
- DOI:
- 10.4238/vol8-2gmr564
Characterization of the nucleolar cycle and chromatoid body formation in the spermatogenesis of some vertebrate species
Authors: R.L. Peruquetti
-.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2TA017
- DOI:
- 10.4238/vol8-2TA017
XPG polymorphisms are associated with prognosis of advanced non-small cell lung cancer treated with platinum-based doublet chemotherapy
Authors: H.Z. Zou and Y.Q. Zhao
We conducted a cohort study to investigate whether 3 potential single nucleotide polymorphisms (SNPs) in the xeroderma pigmentosum complementation group G (XPG) gene could predict the survival of advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based doublet chemotherapy. We enrolled 262 patients with histologically confirmed NSC.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.26.3
- DOI:
- 10.4238/2015.January.26.3
A proposed selection index for feedlot profitability based on estimated breeding values
Authors: R.R. van der Westhuizen and J. van der Westhuizen
It is generally accepted that feed intake and growth (gain) are the most important economic components when calculating profitability in a growth test or feedlot. We developed a single post-weaning growth (feedlot) index based on the economic values of different components. Variance components, heritabilities and genetic corre.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2gmr599
- DOI:
- 10.4238/vol8-2gmr599