Human Genetics
Phenotypic and RAPD diversity among 80 germplasm accessions of the medicinal plant isabgol (Plantago ovata, Plantaginaceae)
Authors: N. Singh, R.K. Lal and A.K. Shasany
Plantago ovata, popularly known as isabgol, has great commercial and medicinal importance due to thin rosy white membranous seed husk. Isabgol seeds and husks have emollient, demulcent and laxative properties. We used both biometric and molecular techniques to assess the genetic variability and relatedness of 80 germplasm acce.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr583
- DOI:
- 10.4238/vol8-4gmr583
SSR analysis demonstrates that olive production in the southern Marmara region in Turkey uses a single genotype
Authors: A. Ipek, E. Barut, H. Gulen, A.T. Oz, N.A. Tangu and M. Ipek
The southern Marmara region in Turkey was surveyed to determine the olive cultivars that are used for olive production. Genetic diversity analysis using simple sequence repeat (SSR) markers indicated that the cultivar Gemlik is the major olive cultivar grown in this region, while other olive cultivars are grown only for use as.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr659
- DOI:
- 10.4238/vol8-4gmr659
Concurrent sequence variation of TP53 and TP73 genes in anaplastic astrocytoma
Authors: N.P. Anselmo, J.A. Rey, L.O. Almeida, A.C. Cust�³dio,J.R.W. Almeida, C.A. Clara, M.J. Santos and C. Casartelli
Disruption or loss of tumor suppressor gene TP53 is implicated in the development or progression of almost all different types of human malignancies. Other members of the p53 family have been identified. One member, p73, not only shares a high degree of similarity with p53 in its primary sequence, but also has similar function.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr631
- DOI:
- 10.4238/vol8-4gmr631
Salt stress causes a shift in the localization pattern of germin gene expression
Authors: M. Caliskan
The response of plants to biotic and abiotic stress factors involves biochemical, physiological, morphological, and developmental changes. Salt stress has been the subject of extensive studies due to the low salt tolerance of many crop plants. Germin and germin-like gene products are known to be involved in various aspects of .. Read More»
- Genet. Mol. Res. 8(4):
An assessment of genetic variability and relationships among wild-grown blackthorn (Prunus spinosa L.) plants based on RAPD markers
Authors: Y. Erturk, S. Ercisli, D. Maghradze, E. Orhan and G. Agar
Prunus spinosa, blackthorn, exists as wild populations that inhabit uncultivated uplands of Coruh Valley in the northeastern part of Turkey; the fruit is used to make preserves. We examined genetic diversity in wild-grown Prunus spinosa; 16 individual plants from wild populations of Coruh Valley were sampled and subjected to R.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr641
- DOI:
- 10.4238/vol8-4gmr641
Buccal micronucleus frequency is associated with age in Down syndrome
Authors: F.L.S. Ferreira, D. Pr�¡, M.G. Martino-Roth and G.L. Garcias
Down syndrome has been linked to premature aging and genomic instability. We examined the frequency of micronucleus (MN) and binucleated cells in the oral mucosa of Down syndrome patients and healthy controls matched by age and gender, addressing the effect of age and family income. Down syndrome individuals had an increased n.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr636
- DOI:
- 10.4238/vol8-4gmr636
FISH analysis and cytogenetic characterization of male meiotic prophase I in Acricotopus lucidus (Diptera, Chironomidae)
Authors: W. Staiber
In the chironomid Acricotopus lucidus, two cells with quite different chromosome complements arise from the last unequal spermatogonial mitosis, as a consequence of monopolar migration of the so-called germ line limited chromosomes (Ks). The cell receiving all the Ks, in addition to two sets of the regularly segregating somati.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr664
- DOI:
- 10.4238/vol8-4gmr664
Cytogenetic findings in an epithelioid sarcoma with angiomatoid features. A case report
Authors: M.S. Brassesco, E.T. Valera, A.M. Castro-Gamero, D.A. Moreno,T.P. Silveira, B.M. Mori, E.E. Engel4, C.A. Scrideli and L.G. Tone
Epithelioid sarcoma is a rare, aggressive soft tissue tumor of unknown histogenesis showing predominantly epithelioid cytomorphology. We conducted a conventional and molecular cytogenetic study of a 27-year-old male with epithelioid sarcoma with angiomatoid features. Cytogenetic analysis of epithelioid sarcoma metaphase spread.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr656
- DOI:
- 10.4238/vol8-4gmr656
Evaluation of the effects of androgen receptor gene trinucleotide repeats and prostate-specific antigen gene polymorphisms on prostate cancer
Authors: D. Alptekin, M. Izmirli, Y. Bayazit, H.U. Luleyap, M.B. Yilmaz, B. Soyupak, M.A. Erkoc and Z. Tansug
The number of trinucleotide repeats [CAG (coding for polyglutamine), GGC (coding for polyglycine)] in the first exon of the androgen receptor (AR) gene and prostate-specific antigen (PSA) gene androgen response element I A/G polymorphism are both related to prostate cancer prognosis. We investigated whether these genomic chang.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.1
- DOI:
- 10.4238/2012.May.18.1
Association of TP53 gene codon 72 polymorphism with endometriosis in Mexican women
Authors: M.P. Gallegos-Arreola, L.E. Figuera-Villanueva, A.M. Puebla-P�©rez, H. Montoya-Fuentes, A.E. Suarez-Rincon and G.M. Z�º�±iga-Gonz�¡lez
The TP53 tumor suppressor gene plays an important role in cell cycle regulation; polymorphisms of this gene have been associated with endometriosis. We examined the role of TP53 codon 72 polymorphism by comparing genotypes of 235 healthy Mexican women (controls with surgically excluded endometriosis) with the genotypes of 151 .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.15.10
- DOI:
- 10.4238/2012.May.15.10