Human Genetics
Interspecific hybridization between Tigridia pavonia and T. augusta through ovary slice culture
Authors: J.-L. PiÃ?±a-Escutia L.-M. VÃ?¡zquez-GarcÃ?Âa A.-M. Arzate-FernÃ?¡ndez
Tigridia pavonia is the most popular species in the Tigridia genus, and is currently marketed in Europe, Asia, and Australia as a landscape plant. Although it is native to Mexico, there are no breeding programs for it. In this study, we attempted to increase its flower color spectrum and growth habit by interspecific hybridization with T. augusta. Intersp.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.4
- DOI:
- 10.4238/2013.January.16.4
Allelic frequencies and statistical data obtained from 15 STR loci in a population of the Goi�¡s State
Authors: T.C. Vieira D.M. Silva M.A.D. Gigonzac V.L. Ferreira M.W. Gon�§alves A.D da Cruz
Due to the miscegenation of the Brazilian population, the central region of Brazil was colonized by internal migration of individuals from different origins, who contributed to the genetic diversity existing in this population. The purpose of this study was to estimate population parameters based on the allele frequencies for 15 polymorphic autosomal short-t.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.5
- DOI:
- 10.4238/2013.January.16.5
Assessment of BCL2/J(H) translocation in healthy individuals exposed to low-level radiation of 137CsCl in Goi�¢nia, Goi�¡s, Brazil
Authors: H.F. Nunes A.B.A. Laranjeira J.A. Yunes E.O.A. Costa C.O. de A. Melo D. de M. e Silva A.D. da Cruz
Healthy radio-exposed individuals who received low levels of Cesium-137 radiation during the accident that occurred in GoiÃ?¢nia in 1987, their families and controls were tested for the detection of t(14;18)-rearranged B cells in peripheral blood by using a highly sensitive, real-time quantitative PCR method. The chromosomal translocation t(14;18)(q32;q21) .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.16.6
- DOI:
- 10.4238/2013.January.16.6
Association study between Y-chromosome haplogroups and susceptibility to spermatogenic impairment in Han People from southwest China
Authors: J. Ran T.T. Han X.P. Ding X. Wei L.Y. Zhang Y.P. Zhang T.J. Li S.S. Nie L. Chen
The non-recombining portion of the Y-chromosome contains numerous polymorphisms; therefore, it is now the most informative haplotyping system with wide-ranging applications. Idiopathic azoospermia and oligospermia are among the most important causes of male infertility. Different haplogroups may have different genetic backgrounds, which may be either suscept.. Read More»
- Genet. Mol. Res. 12(1):
- 2012.January.22.4
- DOI:
- 10.4238/2012.January.22.4
Carbon source-induced changes in the physiology of the cacao pathogen Moniliophthora perniciosa (Basidiomycetes) affect mycelial morphology and secretion of necrosis-inducing proteins
Authors: F.C. Alvim1, E.M. Mattos1, C.P. Pirovani1, K. Gramacho2, C. Pungartnik1, M. Brendel1, J.C.M. Cascardo1 and M. Vincentz3
Quantitative and qualitative relationships were found between secreted proteins and their activity, and the hyphal morphology of Moniliophthora perniciosa, the causal agent of witches’ broom disease in Theobroma cacao. This fungus was grown on fermentable and non-fermentable carbon sources; significant differences in mycelial morphology we.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr619
- DOI:
- 10.4238/vol8-3gmr619
The genetic variant rs401681C/T is associated with the risk of non-small cell lung cancer in a Chinese mainland population
Authors: H. Wang Y. Zhao J. Ma G. Zhang Y. Mu G. Qi Z. Fang L. Wang Q. Fan Z. Ma
Although lung cancer (LC) is a highly environmentally associated disease, genetic factors are also thought to play a role in this disease. In recent years, genome-wide association studies have identified various susceptible genetic regions for LC. Herein, we used high-resolution melting analysis to genotype 2 significant single nucleotide polymorphisms pr.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.22.5
- DOI:
- 10.4238/2013.January.22.5
RIG-I detects HIV-1 infection and mediates type I interferon response in human macrophages from patients with HIV-1-associated neurocognitive disorders
Authors: M.Q. Wang, Y.L. Huang, J. Huang, J.L. Zheng and G.X. Qian
The aim of this study was to explore the precise role of retinoic acid-inducible gene-I (RIG-I) signaling in human immunodeficiency virus type 1 (HIV-1)-infected macrophages from patients with HIV-1-associated neurocognitive disorders (HAND). Postmortem brain tissues were collected from patients with HIV-1-associated dementia and were compared to samples .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.42
- DOI:
- 10.4238/2015.October.28.42
Regularized quantile regression applied to genome-enabled prediction of quantitative traits
Authors: M. Nascimento, F.F. e Silva, M.D.V. de Resende, C.D. Cruz,A.C.C. Nascimento, J.M.S. Viana, C.F. Azevedo, L.M.A. Barroso
Genomic selection (GS) is a variant of marker-assisted selection, in which genetic markers covering the whole genome predict individual genetic merits for breeding. GS increases the accuracy of breeding values (BV) prediction. Although a variety of statistical models have been proposed to estimate BV in GS, few methodologies h.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019538
- DOI:
- 10.4238/gmr16019538
Demographic characterization of Brazilian patients enrolled in the Fabry Registry
Authors: A.M. Martins S.O. Kyosen J. Garrote F.M.V. Marques J.G. Guilhem E. Macedo J. Sobral Neto S. Ura
Fabry disease (FD) is an X-linked inborn error of metabolism caused by alpha-galactosidase A deficiency. The Fabry Registry is an ongoing observational database that compiles clinical data on patients with FD. We analyzed the Fabry Registry data of patients enrolled in Brazil to characterize the demographic and baseline clinical characteristics of this pa.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.5
- DOI:
- 10.4238/2013.January.24.5
Cross-species amplification of selected zebrafish, central stoneroller, and finescale dace microsatellites in lake minnow populations
Authors: D. Kaczmarczyk
Fifteen sets of PCR primers designed for the amplification of microsatellite loci from Danio rerio and Phoxinus neogaeus Campostoma DNA that have been proven applicable for molecular studies of several species of cyprinids were tested for amplification of microsatellites from lake minnow DNA. The samples were taken from 298 fish inhabiting 6 distinct popu.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.7
- DOI:
- 10.4238/2013.January.24.7