Human Genetics
Angiotensin II type 1 receptor gene A1166C polymorphism and breast cancer susceptibility
Authors: L. Li, F. Wang, P.W. Lv, M.Z. Zhu, J.J. He, G.C. Guo, Y.T. Gu and M.L. Han
Numerous studies have evaluated the association between the angiotensin II type-1 receptor (AGTR1) gene A1166C polymorphism and breast cancer risk. However, the specific association is controversial. The aim of the present study was to derive a more precise estimation of the relationship. A comprehensive research was conducted.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.9
- DOI:
- 10.4238/2015.November.24.9
Drug resistance analysis of bacterial strains isolated from burn patients
Authors: L.F. Wang, J.L. Li, W.H. Ma and J.Y. Li
This study aimed to analyze the spectrum and drug resistance of bacteria isolated from burn patients to provide a reference for rational clinical use of antibiotics. Up to 1914 bacterial strain specimens isolated from burn patients admitted to hospital between 2001 and 2010 were subjected to resistance monitoring by using the K-B paper disk method. Retros.. Read More»
- Genet. Mol. Res. 13(4):
Analysis of the dynamic changes in the soft palate and uvula in obstructive sleep apnea-hypopnea using ultrafast magnetic resonance imaging
Authors: Y.L. Wang1, J.P. Mcdonald2, Y.H. Liu3, K.F. Pan4, X.H. Zhang5 and R.D. Hu1
Apnea and the respiratory cycle are dynamic processes in obstructive sleep apnea-hypopnea (OSAH), which occur only during sleep. Our study aimed to observe the dynamic changes in the soft palate and the uvula during wakefulness and sleep using ultrafast magnetic resonance imaging (UMRI) to provide reference data for the pathogenesis and treatment of OSAH... Read More»
- Genet. Mol. Res. 13(4):
Effects of rehabilitation management on gastric emptying function in older adults with diabetes
Authors: Z.M. Shao1*, J.F. Yao2*, J. Chen2*, Z.W. Yu3, X.F. Yu2, J.J. Zheng3, X. Tang4
The relationship between gastric emptying dysfunction and blood glucose concentration in elderly with type 2 diabetes mellitus was investigated, and the effect of rehabilitation exercise prescription training on gastric emptying in the geriatric diabetic patients was evaluated. A total of 160 older type 2 diabetic adults and 30 cases of non-diabetic patie.. Read More»
- Genet. Mol. Res. 13(4):
Analysis of the BRAF V600E mutation in primary cutaneous melanoma
Authors: J.S.S. Inumaru1, K.I.F. Gordo, A.C. Fraga Junior, A.M.T.C. Silva, C.B.Q.S. Leal, F.M. Ayres, I.J. Wastowski, N.F. Borges and V.A. Saddi
BRAF V600E is the most common mutation in cutaneous melanomas, and has been described in 30-72% of such cases. This mutation results in the substitution of valine for glutamic acid at position 600 of the BRAF protein, which consequently becomes constitutively activated. The present study investigated the BRAF V600E mutation fr.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.22.8
- DOI:
- 10.4238/2014.January.22.8
Comparative study of emergence agitation between isoflurane and propofol anesthesia in adults after closed reduction of distal radius fracture
Authors: G.Y. Liu, Z.Q. Chen and Z.W. Zhang
Distal radius fracture is a common wound. It is reduced by surgery under anesthesia. Emergence agitation can often occur after anesthesia. It is associated with increased morbidity and hospital costs. However, there have been almost no reports in the medical literature on the occurrence of emergence agitation in adults. This study aimed to compare emergen.. Read More»
- Genet. Mol. Res. 13(4):
Boric acid increases the expression levels of human anion exchanger genes SLC4A2 and SLC4A3
Authors: F. Akbas and Z. Aydin
Boron is an important micronutrient in plants and animals. The role of boron in living systems includes coordinated regulation of gene expression, growth and proliferation of higher plants and animals. There are several well-defined genes associated with boron transportation and tolerance in plants and these genes show close h.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.3.6
- DOI:
- 10.4238/2012.April.3.6
Effects of partial tonsillectomy on the immune functions of children with obstructive sleep apnea-hypopnea syndrome at early stage
Authors: Z.Y. Dai, D.Y. Huang and C.Y. Zhou
The purpose of this study was to investigate the changes in the humoral and cellular immunity of children with obstructive sleep apnea-hypopnea syndrome and hypertrophy of tonsils before and after plasma-mediated temperature-controlled radiofrequency ablation treatment. Fifty-seven children suffering from obstructive sleep apn.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.15
- DOI:
- 10.4238/2014.January.24.15
Unruptured saccular aneurysm presenting migraine
Authors: M. Zhao, C.S. Liu, X.Y. Xu, Y.P. Xiao and C. Fang
Headache can be attributed to cranial or cervical vascular disorders including ischemic stroke or transient ischemic attack, non-traumatic intracranial hemorrhage, unruptured vascular malformation, arteritis, carotid-vertebral artery pain, and cerebral venous thrombosis. Here, we present a case report of unruptured saccular an.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.19
- DOI:
- 10.4238/2014.January.24.19
Polymorphisms of DNA repair-related genes with susceptibility and prognosis of prostate cancer
Authors: X.J. Zhang, P. Liu and F. Zhu
We aimed to investigate the association between genetic variants of the DNA repair genes XPG, CSB, XPC, CCNH, and MMS19L in the nucleotide excision repair (NER) pathway and risk of prostate cancer in a population in China. This study included 229 patients with newly diagnosed and histopathologically confirmed primary prostate .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.20
- DOI:
- 10.4238/2014.January.24.20