Human Genetics
Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells
Authors: Q. Li, C.-F. Chen, D.-Y. Wang, Y.-T. L�¼, Y. Huan, S.-X. Fang,Y. Han, R.-C. Ge and X.-W. Ch
-.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027526
- DOI:
- 10.4238/gmr.15027526
Myoglobin A79G polymorphism association with exercise-induced skeletal muscle damage
Authors: T. Cui and M.S. Jiang
We assessed the role of A79G, a polymorphism of the myoglobin gene (MB), in susceptibility to exercise-induced skeletal muscle damage. Between January 2012 and December 2014, a total of 166 cases with exercise-induced skeletal muscle damage and 166 controls were recruited into our study. Genotyping of MB A79G was carried out u.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027506
- DOI:
- 10.4238/gmr.15027506
ERCC2 rs13181 polymorphism association with glioma susceptibility in a Chinese population
Authors: X. Gao, Y.J. Tang, G.F. Zhang, L. Yu and S.T. Qi
We conducted a case-control study to investigate the role of ERCC2 rs13181 polymorphism in glioma development. A total of 165 patients who were histopathologically diagnosed to have gliomas and 330 controls were collected at Jiujiang First People’s Hospital between July 2012 and June 2014. The ERCC2 rs13181 polymorphism .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027585
- DOI:
- 10.4238/gmr.15027585
Balance between inflammatory and regulatory cytokines in systemic lupus erythematosus
Authors: Y. Yao, J.B. Wang, M.M. Xin, H. Li, B. Liu, L.L. Wang, L.Q. Wang and L. Zhao
To investigate the cytokine profile in serum and cerebrospinal fluid (CSF) from patients with systemic lupus erythematosus (SLE) and central nervous system infection, we measured interferon-g (IFN-g), interleukin-1b (IL-1b), IL-4, IL-6, IL-8, IL-10, and IL-17 levels in serum and CSF from 50 SLE patients and 38 matched controls.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027626
- DOI:
- 10.4238/gmr.15027626
Association of CYP1A1 MspI polymorphism with oral cancer risk in Asian populations: a meta-analysis
Authors: J.L. Xu, R. Xia, L. Sun, X. Min, Z.H. Sun, C. Liu, H. Zhang and Y.M. Zhu
Numerous studies regarding the association between the CYP1A1 MspI polymorphism and oral cancer risk in Asian populations have shown controversial results. To get a more precise estimation of this relationship, we conducted a comprehensive meta-analysis. PubMed, the Cochrane Library, Elsevier Science Direct, Web of Knowledge, .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027688
- DOI:
- 10.4238/gmr.15027688
Decreased miR-452 expression in human colorectal cancer and its tumor suppressive function
Authors: T. Tang, G.C. Zhang, C.F. Li, Y.F. Liu and W.Y. Wang
-.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027730
- DOI:
- 10.4238/gmr.15027730
Nuclear magnetic resonance-based study reveals the metabolomics profile of nasopharyngeal carcinoma
Authors: Y. Wang, X. Luo, G.H. Zhang and S.L. Li
Proton nuclear magnetic resonance ([1H]-NMR) spectroscopy has been used to investigate metabolites in serum and several types of tissue. We used NMR spectroscopy to explore the differential metabolic profiles in serum from nasopharyngeal carcinoma (NPC) patients. Moreover, metabolites with potential as biomarkers for identifyi.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027796
- DOI:
- 10.4238/gmr.15027796
HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes
Authors: Y.L. Hu, D. Zhong, F. Pang, Q.Y. Ning, Y.Y. Zhang, G. Li, J.Z. Wu and Z.N. Mo
Prostate cancer is one of the most commonly diagnosed male malignancies. Genome wide association studies have revealed HNF1b to be a major risk gene for prostate cancer susceptibility. We examined the mechanisms of involvement of HNF1b in prostate cancer development. We integrated data from Gene Expression Omnibus prostate cancer genes from the Dragon Dat.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.4
- DOI:
- 10.4238/2013.April.25.4
Enhancement of recombinant adeno-associated virus mediated transgene expression by targeted echo-contrast agent
Authors: S.L. Yang, Y.M. Mu, K.Q. Tang, X.K. Jiang, W.K. Bai, E. Shen and B. Hu
Ultrasound-targeted microbubble destruction (UTMD) has been recently developed for destroying bubbles carrying drugs or genes, thereby permitting local release of these target molecules. We investigated whether SonoVue®, a new contrast agent that contains phospholipid-stabilized microbubbles filled with sulfur hexafluoride vapor, is effective at deliv.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.25.3
- DOI:
- 10.4238/2013.April.25.3
ERCC1 C118T polymorphism has predictive value for platinum-based chemotherapy in patients with late-stage bladder cancer
Authors: Z.C. Xu, H.Z. Cai, X. Li, W.Z. Xu, T. Xu, B. Yu, Q. Zou and L. Xu
This study aims to investigate the association between ERCC1 codon C118T polymorphism and the response rate of platinum-based chemotherapy in patients with late-stage bladder cancer. A total of 41 eligible patients histologically confirmed as having stage IV muscle-invasive transitional cell carcinoma of the bladder were treat.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027801
- DOI:
- 10.4238/gmr.15027801