Human Genetics
Association between interleukin gene polymorphisms and risk of recurrent oral ulceration
Authors: C. Jing and J.-Q. Zhang
We conducted a case-control study to investigate the association between the functional IL-1β+3954 (C/T), IL-6-174 (G/C), IL-10-1082 (G/A), and IL-10-819C/T genetic polymorphisms and risk of recurrent oral ulceration (ROU) in a Chinese population. Polymorphisms of IL-1β+3954C/T, IL-6-174G/C, IL-10-1082A/G and IL-10-819C/T were assessed by polyme.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.26
- DOI:
- 10.4238/2015.June.18.26
Genetic background of Escherichia coli isolates from peritoneal dialysis patients with peritonitis and uninfected control subjects
Authors: Y.F. Li1,, N. Su, S.Y. Chen, W.X. Hu, F.F. Li, Z.P. Jiang and X.Q. Yu
Escherichia coli is the most common cause of Gram-negative peritonitis resulting in peritoneal function deterioration as well as poor clinical outcome in continuous ambulatory peritoneal dialysis (PD) patients. In this study, we analyzed the phylogenetic background and genetic profile of the E. coli isolates and sought to dete.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017341
- DOI:
- 10.4238/gmr.15017341
Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions
Authors: Y. Liu, W.-J. Liao, Z. Zhu, H. Zeng, H.-Q. He, X.-L. Sun, X.-F. Xu, L. Huang, W.-M. Wang, X.-Y. Zhou and Y.-Z. He
The protective effect of procyanidine and its oligomers against high glucose-mediated oxidative stress injury in endothelial progenitor cells (EPCs), and effect of procyanidin on vascular endothelial growth factor receptor-2 (VEGFR-2) expression and downstream signal pathway were analyzed in vitro. Rat bone marrow mononuclear cells were isolated, cultured.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016925
- DOI:
- 10.4238/gmr.15016925
Expression of TNF-�±, VEGF, and MMP-3 mRNAs in synovial tissues and their roles in fibroblast-mediated osteogenesis in ankylosing spondylitis
Authors: K.G. Liu, Q.H. He, J.W. Tan and G.J. Liao
The aim of this study was to explore the mRNA levels of tumor necrosis factor-α (TNF-α), vessel endothelial growth factor (VEGF), and matrix metalloproteinase-3 (MMP-3) in synovial tissues in ankylosing spondylitis (AS), and to analyze the functions of these proteins in the differentiation of AS synovial tissue fibroblasts into osteoblasts (OB.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.28
- DOI:
- 10.4238/2015.June.18.28
Identification of sequence-related amplified polymorphism markers linked to the red leaf trait in ornamental kale (Brassica oleracea L. var. acephala)
Authors: Y.S. Wang, Z.Y. Liu, Y.F. Li, Y. Zhang, X.F. Yang and H. Feng
Artistic diversiform leaf color is an important agronomic trait that affects the market value of ornamental kale. In the present study, genetic analysis showed that a single-dominant gene, Re (red leaf), determines the red leaf trait in ornamental kale. An F2 population consisting of 500 individuals from the cross of a red leaf double-haploid line â.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.3
- DOI:
- 10.4238/2013.April.2.3
Apomixis in cassava: advances and challenges
Authors: D.Y.H. Freitas and N.M.A. Nassar
Cassava is the most important staple crop in the Tropics and Subtropics. Apomixis may revolutionize its production due to various attributes. These potential advantages include production by true seed, maintaining cultivar superiority over generations without segregation, and avoiding contamination by bacteria and viruses. Historically, apomixis was initi.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.14
- DOI:
- 10.4238/2013.April.2.14
BMP6 and BMP4 expression in patients with cancer-related anemia and its relationship with hepcidin and s-HJV
Authors: Y.J. Shi and X.T. Pan
In the present study, we investigated BMP6 and BMP4 expression in patients with cancer-related anemia (CRA) as well as its relationship with hepcidin and s-HJV. The avidin-biotin system enzyme-linked immunosorbent assay was used to test serum levels of BMP6, BMP4, s-HJV, and hepcidin in 53 cancer patients with anemia and 52 control cancer patients without.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017130
- DOI:
- 10.4238/gmr.15017130
Prevalence of human papillomavirus genotypes among women with cervical lesions in the Shaanxi Province of China
Authors: J. Li, Y.Y. Wang, X. Nan, X.F. Tian, T. Yan, P. Wang, Y. Yin, Y. Liu, R. Yuan, G.Q. Wang and Y.L. Fu
This study aimed to investigate human papilloma virus (HPV) genotypes among women with cervical lesions in Shaanxi Province, China, to obtain information regarding cervical lesion prevention and treatment. The study included 4508 HPV-positive subjects; cervical swab specimens were collected and tested for HPV infection status and HPV genotypes using polym.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017181
- DOI:
- 10.4238/gmr.15017181
Complementary DNA cloning, sequence analysis, and tissue transcription profile of a novel U2AF2 gene from the Chinese Banna mini-pig inbred line
Authors: S.Y. Wang, J.L. Huo, Y.W. Miao, W.M. Cheng and Y.Z. Zeng
U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an important gene for pre-messenger RNA splicing in higher eukaryotes. In this study, the Banna mini-pig inbred line (BMI) U2AF2 coding sequence (CDS) was cloned, sequenced, and characterized. The U2AF2 complete CDS was amplified using the reverse transcription-polymerase chain reaction (RT-PCR) technique.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.9
- DOI:
- 10.4238/2013.April.2.9
Population structure of the blood clam (Tegillarca granosa) in China based on microsatellite markers
Authors: Y.J. Wang, Q.G. Zeng and L.N. Xu
The blood clam, Tegillarca granosa, is widely cultivated in China. We isolated 6 microsatellite loci from T. granosa and used them to investigate genetic diversity and population structure of 5 widely distributed populations of blood clam collected from eastern and southeastern China. The allele number per locus varied from 4 to 9, and the polymorphism in.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.6
- DOI:
- 10.4238/2013.April.2.6