Human Genetics
Effect of weaning age on cortisol release in piglets
Authors: L.A. Li, J.J. Yang, Y. Li, L. Lv, J.J. Xie, G.M. Du, T.M. Jin, S.Y. Qin and X.L. Jiao
The effect of weaning age on the adrenal cortex, which plays a vital role in the stress response, is currently unknown. Therefore, plasma adrenocorticotropic hormone (ACTH) and cortisol levels, weights and relative weights of adrenal glands, and steroidogenesis-related protein and enzyme expression levels in piglets weaned on .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027693
- DOI:
- 10.4238/gmr.15027693
DNA-based identification of forensically important species of Sarcophagidae (Insecta: Diptera) from Rio de Janeiro, Brazil
Authors: K.S. Napole�£o, C.A. Mello-Patiu, J. Oliveira-Costa, D.M. Takiya,R. Silva and R.S. Moura-Neto
Sarcophagidae, or flesh flies, are of great importance in forensic entomology, but their effective application requires precise taxonomic identification, which relies almost exclusively on characteristics of the male genitalia. Given that female flies and larvae are most abundant in animal carcasses or on corpses, precise morp.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027705
- DOI:
- 10.4238/gmr.15027705
Changes in the PD-1 and PD-L1 expressions of splenic dendritic cells in multiple-organ dysfunction syndrome mice and their significance
Authors: Q. Liu, J.Y. Lu, X.H. Wang, B.J. Qu, S.R. Li and J.R. Kang
The aim of this study was to evaluate the expression of surface molecules in splenic dendritic cells (DC) in multiple-organ dysfunction syndrome (MODS) mice and their effects on the immunosuppression of sepsis and MODS. One hundred thirty C57BL/6 mice were divided into 7 groups: 6, 12, 24, 48 h, 5-7 days, 10-12 days, and the n.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.4
- DOI:
- 10.4238/2014.September.26.4
Evaluation of the semen swim-up method for bovine sperm RNA extraction
Authors: C.M. Han, R. Chen, T. Li, X.L. Chen, Y.F. Zheng, M.T. Ma and Q.H. Gao
Isolation of high-quality RNA is important for assessing sperm gene expression, and semen purification methods may affect the integrity of the isolated RNA. This study evaluated the effectiveness of the sperm swim-up method for seminal RNA isolation. Frozen semen samples in straws from three bulls of proven fertility were puri.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027713
- DOI:
- 10.4238/gmr.15027713
Acrocomia aculeata prevents toxicogenetic damage caused by the antitumor agent cyclophosphamide
Authors: M.F. Magosso, P.C. Carvalho, B.U.C. Shneider, L.R. Pessatto,J.R. Pesarini, P.V.B. Silva, W.A. Correa, C.A.L. Kassuya, R.M. Muzzi and R.J. Oliveira
Acrocomia aculeata is a plant rich in antioxidant compounds. Studies suggest that this plant has anti-inflammatory, antidiabetic, and diuretic potential. We assessed the antigenotoxic, antimutagenic, immunomodulation, and apoptotic potentials of A. aculeata alone and in combination with an antitumor agent, cyclophosphamide. Sw.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027816
- DOI:
- 10.4238/gmr.15027816
Molecular identification and genetic variation of varieties of Styphnolobium japonicum (Fabaceae) using SRAP markers
Authors: R.X. Sun, C.H. Zhang, Y.Q. Zheng, Y.C. Zong, X.D. Yu and P. Huang
Thirty-four Styphnolobium japonicum varieties were analyzed using sequence-related amplified polymorphism (SRAP) markers, to investigate genetic variation and test the effectiveness of SRAP markers in DNA fingerprint establishment. Twelve primer pairs were selected from 120 primer combinations for their reproducibility and hig.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027837
- DOI:
- 10.4238/gmr.15027837
BK polyomavirus association with colorectal cancer development
Authors: M.N. Khabaz, T. Nedjadi, M.A. Gari, J.A. Al-Maghrabi, H.M. Atta, A.A. Basuni and D.A. Elderwi
The development of human neoplasms can be provoked by exposure to one of several viruses. Burkitt lymphoma, cervical carcinoma, and hepatocellular carcinoma are associated with Epstein-Barr, human papilloma, and hepatitis B virus infections, respectively. Over the past three decades, many studies have attempted to establish an.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027841
- DOI:
- 10.4238/gmr.15027841
Clinical and genetic analyses of Chinese patients with Gitelman syndrome
Authors: M. Miao, C.Q. Zhao, X.L. Wang and Z.Y. Shan
To evaluate the genotype-phenotype relationship of Gitelman syndrome in Chinese patients. We selected patients with Gitelman syndrome presenting hypokalemia. Medical history, clinical manifestations, laboratory test results, and imaging data of these patients were collected for analysis. Target gene sequencing was performed to.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027859
- DOI:
- 10.4238/gmr.15027859
Polymorphisms in the vascular endothelial growth factor (VEGF) gene associated with asthma
Authors: H.Y. Lu, G.L. Zhao, M.F. Fu
It has been proven that vascular endothelial growth factor (VEGF) is involved in airway restoration and the development of asthma. We sought to examine the relevance of VEGF gene polymorphisms to asthma in the Chinese Han population. We extracted the whole genomic DNA from the peripheral blood of 471 participants, including 22.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027859
- DOI:
- 10.4238/gmr.15027859
Isolation, identification, and degradation performance of a PFOA-degrading strain
Authors: L.B. Yi, L.Y. Chai, Y. Xie, Q.J. Peng and Q.Z. Peng
The perfluorooctanoic acid (PFOA)-degrading strain YAB1 was isolated from the soil near a perfluorinated compound production plant through acclimation and enrichment culture, using PFOA as the sole carbon source. This strain was preliminarily identified as Pseudomonas parafulva based on colony morphology, physiological and bio.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028043
- DOI:
- 10.4238/gmr.15028043