Human Genetics
Identification of CD14 transcript in blood polymorphonuclear neutrophil leukocytes and functional variation in Holsteins
Authors: J.M. Huang, X.G. Wang, Q. Jiang, Y. Sun, C.H. Yang, Z.H. Ju,H.S. Hao, C.F. Wang, J.F. Zhong and H.B. Zhu
Polymorphonuclear neutrophil (PMN) leukocytes are primary phagocytic cells of the bovine mammary gland and a first line of defense against invading pathogens during bovine mastitis infection. Cluster of differentiation 14 (CD14) is mainly expressed in macrophages and neutrophils and acts as a co-receptor that binds bacterial l.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027932
- DOI:
- 10.4238/gmr.15027932
Effects of silver nanoparticles and gold nanoparticles on IL-2, IL-6, and TNF-�± production via MAPK pathway in leukemic cell lines
Authors: C. Parnsamut and S. Brimson
Silver nanopaticles (AgNPs) and gold nanoparticles (AuNPs) have various applications in medical healthcare and various biological properties such as anti-inflammation, anti-cancer, and anti-angiogenesis. In this study, we investigated the effect of AgNPs and AuNPs on cytokine production via the mitogen-activated protein kinase pathway in leukemic cell lin.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.15
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.15
Rapid sedation induced by fentanyl combined with propofol via an intrathecal chemotherapy injection for leukemia in children
Authors: X. Tian,Y.-H. Yang,H.-Y. Wei,J.-Q. Lao,H.-P. Wang and Y.-Y. Tian
This study explored the sedative and analgesic effects of fentanyl combined with propofol via an intrathecal chemotherapy injection for acute leukemia (acute lymphocytic leukemia or acute myelocytic leukemia) among children, to relieve pain and difficulty during intrathecal injection, improve treatment compliance, increase the success rate of single punct.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.18
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.18
Association between IL-10-G1082A polymorphisms and the development of coronary artery disease in a Chinese population
Authors: K. Liang, S.R. Dong and H. Peng
We conducted a case-control study to investigate the association between IL-10-G1082A (rs1800896) polymorphism and the development of coronary artery disease (CAD) in the Chinese population. We recruited 295 CAD patients and 355 healthy controls from the Fifth Affiliated Hospital of Zhengzhou University between April 2012 and .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027933
- DOI:
- 10.4238/gmr.15027933
Simultaneous selection for cowpea (Vigna unguiculata L.) genotypes with adaptability and yield stability using mixed models
Authors: F.E. Torres, P.E. Teodoro, E.V. Rodrigues, A. Santos, A.M. Corr�ªa, G. Ceccon
The aim of this study was to select erect cowpea (Vigna unguiculata L.) genotypes simultaneously for high adaptability, stability, and yield grain in Mato Grosso do Sul, Brazil using mixed models. We conducted six trials of different cowpea genotypes in 2005 and 2006 in Aquidauana, Chapadão do Sul, Dourados, and Primave.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028272
- DOI:
- 10.4238/gmr.15028272
Expression profiles of the apoptosis signaling pathway mediated by death receptor and endoplasmic reticulum in rat liver regeneration
Authors: X.K. Xing, M.H. Li, X.S. Zhu and C.S. Xu
The death receptor and endoplasmic reticulum (ER) are closely related to cell apoptosis, and it is worth studying whether the apoptosis pathways mediated by them are involved in liver regeneration. To understand the mechanism underlying death receptor- and ER-mediated apoptosis during rat liver regeneration, we used the Rat Ge.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028288
- DOI:
- 10.4238/gmr.15028288
Genetic structure of the threatened Hopea chinensis in the Quang Ninh Province, Vietnam
Authors: N.T.P. Trang and L. Triest
Hopea chinensis Hand-Mazz (synonym H. hongayensis Tardieu), is a wind and insect pollinated species. It is a threatened species known only from two locations: Quang Ninh (Vietnam) and Guangxi (China). As an endemic species, it is worth preserving both for dipterocarp biodiversity, as well as for its medicinal use and economic .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028103
- DOI:
- 10.4238/gmr.15028103
Reference gene selection for gene expression studies in lily using quantitative real-time PCR
Authors: M.F. Zhang, Q. Liu and G.X. Jia
Quantitative real-time polymerase chain reaction (qRT-PCR) is an important technology used to analyze gene-expression levels. Reference genes, which are assumed to be expressed consistently across various developmental stages and in different tissues, were selected for expression level analysis. Using digital gene expression t.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027982
- DOI:
- 10.4238/gmr.15027982
Transcript analysis of a goat mesenteric lymph node by deep next-generation sequencing
Authors: G.X. E, Y.J. Zhao, R.S. Na and Y.F. Huang
Deep RNA sequencing (RNA-seq) provides a practical and inexpensive alternative for exploring genomic data in non-model organisms. The functional annotation of non-model mammalian genomes, such as that of goats, is still poor compared to that of humans and mice. In the current study, we performed a whole transcriptome analysis .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028262
- DOI:
- 10.4238/gmr.15028262
Inhibition of subcutaneously implanted human pituitary tumor cells in nude mice by LRIG1
Authors: X. Wang, X.J. He, H.Q. Xu, Z.W. Chen and H.H. Fan
The aim of this study was to explore the inhibition of subcutaneously implanted human pituitary tumor cells in nude mice by LRIG1 and its mechanism. For this study, athymic nude mice were injected with either normal pituitary tumor RC-4B/C cells or LRIG1-transfected RC-4B/C cells. We then calculated the volume inhibition rate .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027681
- DOI:
- 10.4238/gmr.15027681