Human Genetics

Novel transcripts of human cytomegalovirus clinical strain found by cDNA library screening

Authors: Y.P. Ma, Q. Ruan, Y.H. Ji, N. Wang, M.L. Li, Y. Qi, R. He, Z.R. Sun and G.W. Ren

Human cytomegalovirus (HCMV) is a double-stranded DNA virus with the largest genome (~235 kb) of the known human herpes viruses. The coding potential and transcript structures of most HCMV predicted genes have not been identified. New or unknown genes could exist in clinical strains. The SMART (switching mechanism at 5ê�.. Read More»

Genet. Mol. Res. 10(2):

vol10-2gmr1059

DOI:

10.4238/vol10-2gmr1059

A possible role of a cerebral energy gene in alcoholism

Authors: A.F. Ribeiro, D. Correia, R. Boerngen-Lacerda and A.L. Brunialti-Godard

We examined a possible relationship between genes responsible for energy metabolism of the brain and addictive behavior in an animal model. We used non-inbred, Swiss mice exposed to a three-bottle free-choice model [water, 5% (v/v) ethanol, and 10% (v/v) ethanol] over a 16-week period, consisting of four phases: acquisition, w.. Read More»

Genet. Mol. Res. 11(1):

2012.February.17.2

DOI:

10.4238/2012.February.17.2

HPV genotype analysis for women in Shaanxi Province of China

Authors: J. Li, Y.Y. Wang, X.F. Tian, X. Nan, T. Yan, P. Wang, Y.L. Fu and G.Q. Wang

The aim of this study was to examine the subtype distribution of human papilloma virus (HPV) in women in the Shaanxi Province of China. A DNA chip, along with polymerase chain reaction amplification and reverse dot blot technology, was adopted to analyze the HPV genotypes of 22,937 cases of cervical cell specimens. The HPV inf.. Read More»

Genet. Mol. Res. 15(4):

gmr15047178

DOI:

10.4238/gmr15047178

Genetic algorithm-based efficient feature selection for classification of pre-miRNAs

Authors: P. Xuan, M.Z. Guo, J. Wang, C.Y. Wang, X.Y. Liu and Y. Liu

In order to classify the real/pseudo human precursor microRNA (pre-miRNAs) hairpins with ab initio methods, numerous features are extracted from the primary sequence and second structure of pre-miRNAs. However, they include some redundant and useless features. It is essential to select the most representative feature subset; t.. Read More»

Genet. Mol. Res. 10(2):

vol10-2gmr969

DOI:

10.4238/vol10-2gmr969

�?²-casein gene expression by in vitro cultured bovine mammary epithelial cells derived from developing mammary glands

Authors: P.S. Monzani, F.F. Bressan, L.G. Mesquita, J.R. Sangalli and F.V. Meirelles

Epithelial cells from mammary gland tissue that are cultured in vitro are able to maintain specific functions of this gland, such as cellular differentiation and milk protein synthesis. These characteristics make these cells a useful model to study mammary gland physiology, development and differentiation; they can also be use.. Read More»

Genet. Mol. Res. 10(2):

vol10-2gmr1034

DOI:

10.4238/vol10-2gmr1034

Prolactin-releasing peptide mRNA expression in mouse medulla remains relatively stable during pregnancy and lactation

Authors: H.S. Zhu, J.X. Du, Y.Y. Wang, L.F. Wang, L.Q. Hang, G.Y. Yang and Y.L. Wang

We compared levels of prolactin-releasing peptide (PrRP) mRNA expression in mouse medulla at different stages of pregnancy and lactation. Mouse medulla samples were collected on days 6, 12 and 18 of pregnancy and lactation, respectively (six per group), for mRNA. Expression levels of PrRP mRNA in the medulla were measured by s.. Read More»

Genet. Mol. Res. 10(2):

vol10-2gmr1086

DOI:

10.4238/vol10-2gmr1086

Serum ferritin and transferrin saturation levels in �?²0 and �?²+ thalassemia patients

Authors: I.F. Estev�?£o, P. Peitl Junior and C.R. Bonini-Domingos

There have been few studies on the mutations that cause heterozygous beta-thalassemia and how they affect the iron profile. One hundred and thirty-eight individuals were analyzed, 90 thalasemic β0 and 48 thalasemic β+, identified by classical and molecular methods. Mutations in the hemochromatosis (HFE) gene, detecte.. Read More»

Genet. Mol. Res. 10(2):

vol10-2gmr1016

DOI:

10.4238/vol10-2gmr1016

RETRACTION of â�?�?Correlation analysis between an IL-6 genetic polymorphism and non-small cell lung cancer prognosisâ�?, by Zhao K, Xu J, Tian H published in Genetics and Molecular Research 15 (1): 15017021 (2016) DOI: 10.4238/gmr.15017021

Authors: Zhao K, Xu J and Tian H

Genet. Mol. Res. 15(4):

gmr150470211

DOI:

10.4238/gmr150470211

Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma

Authors: X.F. Chen, S. Cai, Q.G. Chen, Z.H. Ni, J.H. Tang, D.W. Xu and X.B. Wang

Recent studies have shown that 5p15.33 is one of the chromosomal regions that is most consistently altered in lung cancer; common variants that are located in this region have been genotyped in various populations. However, the genetic contribution of these variants to carcinogenesis is relatively unknown. A clinic-based case-.. Read More»

Genet. Mol. Res. 11(1):

2012.February.16.2

DOI:

10.4238/2012.February.16.2

Interleukin-8 -251A/T polymorphism and periodontitis susceptibility: a meta-analysis

Authors: Z.J. Yang, X.P. Tang, Q.G. Lai, J.B. Ci and K.F. Yuan

The -251A/T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene has been implicated in susceptibility to periodontitis; however, this correlation has not been elucidated. In this meta-analysis, we investigated the association between the IL-8 -251A/T polymorphism and the risk of periodontitis. All eligible.. Read More»

Genet. Mol. Res. 15(4):

gmr15047379

DOI:

10.4238/gmr15047379