Human Genetics
Frequency distribution of interleukin-10 haplotypes (-1082 A>G, -819 C>T, and-592 C>A) in a Mexican population
Authors: M. V�¡zquez-Villamar, C.A. Palafox-S�¡nchez, J. Hern�¡ndez-Bello,J.F. Mu�±oz-Valle, Y. Valle, A. Cruz, A.I. Alatorre-Meza and E. Oregon-Romero
Interleukin 10 (IL-10) is an immunoregulatory cytokine with multiple roles in the immune system. Three single nucleotide polymorphisms at positions -1082 (A>G), -819 (C>T), and -592 (C>A) in the promoter region of the IL10 gene are believed to be associated with different inflammatory, infectious, and autoimmune disea.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048411
- DOI:
- 10.4238/gmr15048411
Identification of significantly different modules between permanent and deciduous teeth by network and pathway analyses
Authors: J. Kang, R. Bai, K. Liu, X.P. Ji, Y. Li and J.Y. Han
The differences in genetic backgrounds between deciduous and permanent teeth might contribute to the differences in developmental processes, histological characteristics, and tooth life cycles. Here, we attempted to identify significantly different modules between permanent and deciduous teeth via network and pathway analyses... Read More»
- Genet. Mol. Res. 15(4):
- gmr15047959
- DOI:
- 10.4238/gmr15047959
Association between Ser311Cys polymorphism in the dopamine D2 receptor gene and schizophrenia risk: a meta-analysis in Asian populations
Authors: Z.W. Liu, J.L. Liu, Y. An, L. Zhang and Y.M. Wang
Numerous studies have evaluated the association between Ser311Cys (rs1801028, C>G) polymorphism of the dopamine D2 receptor (DRD2) gene and schizophrenia risk. However, the specific association is still controversial. We examined whether DRD2 Ser311Cys polymorphism confers schizophrenia risk in Asian populations. Sixteen st.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.February.8.1
- DOI:
- http://dx.doi.org/10.4238/2012.February.8.1
A case-control study on the risk factors of urinary calculus in Uyghur children in the Kashi region
Authors: H.C. Wang, C. Liu, H.Y. He and M.X. Wang
The incidence of urinary calculus (UC) is very high in Uyghur children in the Kashi region of Xinjiang, China, which seriously affects the growth and life quality of these children. This study was aimed at investigating the risk factors of UC in Uyghur children in Kashi region. One hundred fifteen Uyghur children (age <7 years) with UC who were treated.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.3
- DOI:
- 10.4238/2015.June.1.3
Association between the PPAR�³ Pro12Ala polymorphism and risk of gestational diabetes mellitus: a meta-analysis
Authors: H.L. Shuai, X.Z. Lin, D.L. Chen, P. Li and X. Luo
The relationship between the Pro12Ala polymorphism of PPARγ and the risk of gestational diabetes mellitus remains unresolved. Here, we attempted to resolve this inconsistency. Case-control studies pertaining to the effect of the Pro12Ala polymorphism in the PPARγ protein and risk of gestational diabetes mellitus we.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047682
- DOI:
- 10.4238/gmr15047682
Is there any association between childhood cardiac septal defects and ROCK2 gene polymorphism?
Authors: M. Aksoy, H. Uygun, O. Baspinar, S. Demiryurek, S. Oztuzcu,B. Cengiz, A. Irdem and N.C. Araz
Rho/Rho-kinase pathway plays a critical role in the regulation of cellular functions such as proliferation and migration. One of the possible theories of the development of ventricular septal defects is cell migration disorder. The aim of this study was to analyze the genotype distributions and allele frequencies for the ROCK2 gene Thr431Asn polymorphisms.. Read More»
- Genet. Mol. Res. 13(1):
Human autosomal DNA and X chromosome STR profiles obtained from Chrysomya albiceps (Diptera: Calliphoridae) larvae used as a biological trace
Authors: T.C. Oliveira1,3, A.B.R. Santos2, K.C.N. Rabelo1,3, C.A. Souza3,S.M. Santos3 and S. Crovella1
The use of insects to answer questions in criminal investigations, as well as a combination of forensic genetic techniques to obtain human DNA from the organisms, especially necrophagous dipterians, have gained ground in recent decades among researchers and professionals in this area. The objective of our study was to evaluate.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047622
- DOI:
- 10.4238/gmr15047622
The mutation G298A�Ala100Thr on the coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians
Authors: Angela Cristina Estalote, Rodrigo Proto-Siqueira, Wilson Ara�ºjo Da Silva Jr., Marco Antonio Zago and Marcos Palatnik
Ala100Thr has been suggested to be a Caucasian genetic marker on the FY*B allele. As the Brazilian population has arisen from miscegenation among Portuguese, Africans, and Indians, this mutation could possibly be found in Euro- and Afro-Brazilians, or in Brazilian Indians. Fifty-three related individuals and a random sample of.. Read More»
- Genet. Mol. Res. 4(2):
Outcomes of laryngectomy in elderly patients with laryngeal carcinoma
Authors: R.J. Shi, C.Z. Xu, C.P. Zhang, C.Y. Jiang, Y.Y. Sun, X.J. Yan and P.H. Wang
Laryngeal carcinoma is a common tumor of the head and neck region. This study aimed to examine the outcomes of laryngectomy in elderly patients with laryngeal carcinoma. One-hundred twenty-two patients (male, 117; female, 5) aged 60 years or older (range, 60-94 years) who underwent laryngectomy between 1996 and 2010 were inclu.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.17.23
- DOI:
- 10.4238/2014.March.17.23
Association of eye and neurological diseases
Authors: Sebastiano Bianca, Marco Bianca and Carmela Ingegnosi
-.. Read More»
- Genet. Mol. Res. 4(2):