Human Genetics
Effects of modified Shoutaiwai recipe on integrin �²3 and leukemia-inhibitory factor in endometrium of controlled ovarian hyperstimulation mice during the implantation window
Authors: X.Y. Chen, J. Chen, Z.Y. Wang, X.H. Yu, B.X. Wei and X.H. Wu
We investigated the effects of a modified Shoutaiwai recipe on integrin b3 and leukemia-inhibitory factor (LIF) in the endometrium of controlled ovarian hyperstimulation (COH) mice during the implantation window. Seventy non-pregnant mice were randomly divided into 3 groups: a traditional medicine (TCM) treatment group (N = 30), an aspirin treatment (N = .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.6
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.6
Sexual recombination in Colletotrichum lindemuthianum occurs on a fine scale
Authors: E.A. Souza, O.A. Camargo Jr. and J.M.A. Pinto
Glomerella cingulata f. sp phaseoli is the sexual phase of the fungus Colletotrichum lindemuthianum, the causal agent of common bean anthracnose. This fungus is of great concern, because it causes large economic losses in common bean crops. RAPD markers of five populations of G. cingulata f. sp phaseoli from two Brazilian stat.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr863
- DOI:
- 10.4238/vol9-3gmr863
EGFR gene polymorphisms -216G>T and -191C>A are risk markers for gastric cancer in Mexican population
Authors: J.H. Torres-Jasso, M.E. MarÃ?Ân, E. Santiago-Luna, J.C. Leoner,J. Torres, M.T. MagaÃ?±a-Torres, F.J. Perea, B. Ibarra and J.Y. SÃ?¡nchez-LÃ?³pez
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine-kinase activity that plays an important role in multiple cellular functions. EGFR overexpression has been observed in several types of tumors and it is significantly associated with disease stage, survival, prognosis, and progression of cancer. The polymorphisms -216G>.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.8
- DOI:
- 10.4238/2015.March.13.8
Association between PARK16 gene polymorphisms and susceptibility of Parkinson�s disease in a Chinese population
Authors: H. Xia, Q. Luo, X.X. Li and X.L. Yang
Recent genome-wide association studies identified 11 risk loci in different populations of familial and sporadic Parkinson’s disease (PD) patients. Few loci have been verified in different European and Asian populations. We also validated 2 new single-nucleotide polymorphisms, rs947211 and rs823144, in PARK16 to explore their association with suscep.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.7
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.7
Associations between INSR and MTOR polymorphisms in type 2 diabetes mellitus and diabetic nephropathy in a Northeast Chinese Han population
Authors: A.N. Zhu, X.X. Yang, M.Y. Sun, Z.X. Zhang and M. Li1,
We explored the associations of INSR and mTOR, 2 key genes in the insulin signaling pathway, and the susceptibility to type 2 diabetes mellitus and diabetic nephropathy. Three single-nucleotide polymorphisms (SNPs) (rs1799817, rs1051690, and rs2059806) in INSR and 3 SNPs (rs7211818, rs7212142, and rs9674559) in mTOR were genotyped using the Sequenom MassA.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.9
- DOI:
- 10.4238/2015.March.13.9
Clinical significance of lymphatic vessel invasion in stage I non-small cell lung cancer patients
Authors: K.F. Ma, X.Y. Chu and Y. Liu
The aim of this retrospective study was to evaluate the prognostic influence of lymphatic vessel invasion (LVI) in stage I non-small cell lung cancer (NSCLC) patients. From January 2004 to December 2007, LVI was detected in 57 patients with T1N0M0 NSCLC; therefore, 114 patients with the same pathology, T stage, and surgery method, but without LVI, were se.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.10
- DOI:
- 10.4238/2015.March.13.10
Effects of bisphenol A on decreasing the percentage and promoting the growth of stem cell-like cells from SK-N-SH human neuroblastoma cells
Authors: J.C. Zheng, S.Q. Qi, L. Yang, Y.Y. Ma, K.R. Dong, H.T. Zhu, S.B. Yang, T. Xu, S. Zheng and X.M. Xiao
Bisphenol A (BPA) is an industrial contaminant and is reported to be a risk factor associated with the development of tumors. In our previous studies, we have shown that BPA promoted the growth of SK-N-SH human neuroblastoma cells and increased their invasion and metastasis. In this study, we further investigated the effects of BPA and 17b-estradiol (E2) .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.8
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.8
A new strategy for complete identification of sea buckthorn cultivars by using random amplified polymorphic DNA markers
Authors: G. Yang, J. Ding, L.R. Wu, Y.D. Duan, A.Y. Li, J.Y. Shan and Y.X. Wu
DNA fingerprinting is both a popular and important technique with several advantages in plant cultivar identification. However, this technique has not been used widely and efficiently in practical plant identification because the analysis and recording of data generated from fingerprinting and genotyping are tedious and difficult. We developed a novel app.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.12
- DOI:
- 10.4238/2015.March.13.12
Postpartum pelvic floor function performance after two different modes of delivery
Authors: H. Li, R.F. Wu, F. Qi, A.M. Xiao, Z. Ma, Y. Hu, W.Y. Zhang, W. Li and Z.C. Wang
This study investigated the incidences of urinary incontinence and pelvic organ prolapse as well as pelvic floor muscle strength after cesarean section and vaginal delivery. From June 2010 to July 2011, 149 puerpera in Shenzhen Hospital, Peking University, were divided into the cesarean section group (N = 66) and the vaginal delivery group (N = 83). Postp.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.9
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.9
The L55M polymorphism of paraoxonase-1 is a risk factor for rheumatoid arthritis
Authors: M. Hashemi, A.K. Moazeni-Roodi, A. Fazaeli, M. Sandoughi, M. Taheri, G.R. Bardestani, Z. Zakeri, D.M. Kordi-Tamandani and S. Ghavami
Paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme that exhibits antioxidant and antiatherogenic activities. We examined a possible association between T172A (L55M) and T(-107)C polymorphisms and rheumatoid arthritis. These polymorphisms were determined in 88 rheumatoid arthritis patients and 78 healthy subje.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr893
- DOI:
- 10.4238/vol9-3gmr893