Human Genetics
Genetic divergence through joint analysis of morphoagronomic and molecular characters in accessions of Jatropha curcas
Authors: C.N. Pestana-Caldas, S.A. Silva, E.L. Machado, D.R. de Souza,E.C. Cerqueira-Pereira and M.S. Silva
The aim of this study was to investigate the genetic divergence between accessions of Jatropha curcas through joint analysis of morphoagronomic and molecular characters. To this end, we investigated 11 morphoagronomic characters and performed molecular genotyping, using 23 inter-simple sequence repeat (ISSR) primers in 46 acce.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048385
- DOI:
- 10.4238/gmr.15048385
Optimization of solid-state fermentation conditions for Trichoderma harzianum using an orthogonal test
Authors: J.D. Zhang and Q. Yang
The aim of this study was to develop a protocol for the production of fungal bio-pesticides with high efficiency, low cost, and non-polluting fermentation, while also increasing their survival rate under field conditions. This is the first study to develop biocontrol Trichoderma harzianum transformants TS1 that are resistant to benzimidazole fungicides. A.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.4
- DOI:
- 10.4238/2015.March.13.4
Lack of association between MD-2 promoter gene variants and tuberculosis
Authors: Y. Xue, Z.Q. Zhao, D. Hong, M.Y. Zhao, Y.X. Zhang, H.J. Wang, Y. Wang and J.C. Li
Myeloid differentiation-2 (MD-2) is an essential component of the CD14-TLR4/MD-2 receptor complex involved in microbial cell wall component recognition during infection. Genetic variations in the MD-2 gene may influence human susceptibility to infectious diseases. To date, a predisposition of MD-2 gene variants to contract tub.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr771
- DOI:
- 10.4238/vol9-3gmr771
Association between XRCC1 polymorphisms and laryngeal cancer susceptibility in a Chinese sample population
Authors: W.Q. Wu, L.S. Zhang, S.P. Liao, X.L. Lin, J. Zeng and D. Du
Laryngeal cancer is the major malignant tumor affecting the upper respiratory tract. Previous studies have reported on the association between XRCC1 genetic polymorphisms and risk of laryngeal cancer, but with conflicting results. In this study, we attempted to assess the association between XRCC1 Arg194Trp, Arg280His and Arg3.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048525
- DOI:
- 10.4238/gmr.15048525
c-erbB-2 expression and prognosis of gastric cancer: a meta-analysis
Authors: Z.Q. Wang and B.J. Sun
The prognostic role of c-erbB-2 in gastric cancer is controversial. We conducted a meta-analysis to evaluate the relationship between c-erbB-2 expression and the prognosis of gastric cancer. We evaluated 20 published studies assessing the relationship between c-erbB-2 and gastric cancer prognosis. The Revman 5.0 software was used to perform literature ret.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.5
- DOI:
- 10.4238/2015.March.13.5
Genetic diversity in Tunisian populations of faba bean (Vicia faba L.) based on morphological traits and molecular markers
Authors: I.Z. Backouchi, M. Aouida, N. Khemiri and M. Jebara
Genetic diversity within Vicia faba L. is key to the genetic improvement of this important species. In this study, morphological traits and RAPD molecular markers were used to assess the levels of polymorphism across 12 Tunisian populations, three major and nine minor from different locations. Analysis of morphological traits indicated that the three majo.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.13.2
- DOI:
- 10.4238/2015.July.13.2
Preliminary study of the clonal characteristics of the TCR BV subfamilies in T cells in the peripheral blood from patients with uveitis
Authors: H.-Y. Zou, W.-Z. Yu, Q. Zhang, H.-C. Yang, H.-Y. Huang and M. Jiao
The aim of this study was to investigate the characteristics and polymorphisms of the T-cell receptor BV complementarity-determining region 3 (TCR BV CDR3) gene in peripheral blood mononuclear cells (PBMCs) from patients with uveitis to provide an experimental basis for studying the pathogenesis of this disease. RT-PCR amplifi.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.28.1
- DOI:
- http://dx.doi.org/10.4238/2014.February.28.1
Radiofrequency thermocoagulation combined with pulsed radiofrequency helps relieve postoperative complications of trigeminal neuralgia
Authors: W.-X. Zhao, Q. Wang, M.-W. He, L.-Q. Yang, B.-S. Wu and J.-X. Ni
Trigeminal neuralgia is a sudden, severe condition characterized by stabbing and recurrent pain. Radiofrequency thermocoagulation (RFT) and pulsed radiofrequency (PRF) are common surgical interventions used to treat trigeminal neuralgia. This study aimed to investigate the therapeutic effects and associated complications of a combination of RFT and PRF in.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.13.5
- DOI:
- 10.4238/2015.July.13.5
A multiplex panel of short-amplicon insertion-deletion DNA polymorphisms for forensic analysis
Authors: V.R.D. Santos, H.B. Pena and S.D.J. Pena
We have previously developed a panel of 40 insertion-deletion (INDEL) human DNA polymorphisms that was proven to adequately cover the span of global human genetic diversity. The panel was found to have very low matching probabilities with respect to both the global and Brazilian populations. To optimize the panel for application with degraded DNA samples,.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.2
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.2
Association study of c.910A>G and c.1686C>G polymorphisms in XRCC1 gene with risk of hepatocellular carcinoma in the Chinese population
Authors: W.F. Xia, X.P. Ma, X.R. Li, H. Dong and J.L. Yi
XRCC1 (human X-ray repair complementing defective repair in Chinese hamster cell 1) gene is considered a potentially important gene influencing the risk of hepatocellular carcinoma (HCC). Our analyses detected two allelic variants of XRCC1, c.910A>G and c.1686C>G. We aimed to investigate whether these polymorphisms influ.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.28.3
- DOI:
- http://dx.doi.org/10.4238/2014.February.28.3