Cytogenomics
Diploid chromosome set of kissing bug Triatoma baratai (Hemiptera, Triatominae)
Authors: K.C.C. Alevi, Y.V. Reis, A.O. Borgueti, V.J. Mendon�§a, J.A. Rosa and M.T.V. Azeredo-Oliveira
Triatomines are insects that are taxonomically included in the Hemiptera order and Triatominae subfamily. Based on phenotypic similarity, capacity hybridization, and genetic and ecological aspects, the triatomine species can be grouped into specific complexes and subcomplexes. However, these groupings have not been confirmed. Cytogenetic analyses are importa.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.14
- DOI:
- 10.4238/2015.February.6.14
A novel missense mutation in exon 7 of the ECM1 gene in an Iranian lipoid proteinosis patient
Authors: F. Izadi F. Mahjoubi M. Farhadi M.M. Tavakoli S. Samanian
Lipoid proteinosis (LP) is a rare autosomal recessive disorder. Classical clinical features include warty skin infiltration, papules on the eyelids, skin scarring, as well as extracutaneous abnormalities such as hoarseness of the voice, epilepsy, and neuropsychiatric abnormalities. A defect in the ECM1 gene is responsible for this disease. A 21-year-old fema.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.14.2
- DOI:
- 10.4238/2012.November.14.2
Differentially expressed genes implicated in embryo abortion of mango identified by suppression subtractive hybridization
Authors: J.H. He F.W. Ma Y.Y. Chen H.R. Shu
Embryo abortion in mango severely damages mango production worldwide. The mechanisms by which the mango embryos abort have long been an intriguing question. We used subtractive suppression hybridization to investigate the differentially expressed genes involved in this process. We generated 2 cDNA libraries from normal seed and aborted seed embryos of mango .. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.14.4
- DOI:
- 10.4238/2012.November.14.4
Tissue-specific adaptive levels of glucocorticoid receptor alpha mRNA and their relationship with insulin resistance
Authors: R.B. Castro C.A. Longui C.D.C. Faria T.S. Silva F. Richeti M.N. Rocha M.R. Melo W.L. Pereira E.G. Chamlian L.A. Rivetti
Insulin resistance is an underlying cause of metabolic changes associated with cardiovascular diseases. Glucocorticoids are known determinant factors of insulin resistance. We quantified glucocorticoid receptor alpha (GRĂ?±) mRNA and 11 beta-hydroxysteroid dehydrogenase type 1 (11Ă?²-HSD1) mRNA in various tissues of 35 patients with previously established .. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.21.1
- DOI:
- 10.4238/2012.November.21.1
Role of CASP-10 gene polymorphisms in cancer susceptibility: a HuGE review and meta-analysis
Authors: S. Yan Y.Z. Li J.W. Zhu C.L. Liu P. Wang Y.L. Liu
We investigated a possible association between CASP-10 gene polymorphisms and susceptibility to cancer through a meta-analysis. Eight studies with a total of 29,936 cancer cases and 34,041 healthy controls were included. Meta-analysis results showed that the rs13006529*T carrier was significantly associated with increased cancer risk (OR = 1.17, 95%CI = 1.01.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.26.1
- DOI:
- 10.4238/2012.November.26.1
DNA extraction from fixed cytogenetic cell suspensions
Authors: Amorim MR, Vargas FR, Llerena Junior JC and Pombo-de-Oliveira MS
We developed a procedure for DNA extraction from small volumes of fixed cell suspensions previously prepared for conventional cytogenetic analysis. Good quality DNA was isolated with a fast and simple protocol using DNAzol reagent. This provided suitable DNA for various types of molecular analyses, including polymerase chain r.. Read More»
- Genet. Mol. Res. 6(3):
Plasma human mammaglobin mRNA associated with poor outcome in patients with breast cancer
Authors: G.-W. Lee J.-Y. Kim E.-H. Koh D. Kang D.S. Choi K.-Y. Maeng J.-S. Lee
Different treatment outcomes and prognoses in patients with breast cancer can be observed with similar clinical predictors; this is because the biology of breast cancer is complex and heterogenous, involving multiple unknown contributing factors. We looked for plasma human mammaglobin (hMAM) mRNA by RT-PCR in 82 Korean patients with breast cancer to determin.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.28.2
- DOI:
- 10.4238/2012.November.28.2
Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)
Authors: Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)
Mauritia flexuosa L. (Arecaceae) is a palm tree species known as buriti that occurs in the Cerrado biome. It is characteristic of the vereda, a typical ecosystem of central Brazil. In this phytophysiognomy, M. flexuosa and other groups of arboreal-herbaceous species develop in open fields with very humid soils. M. flexuosa can be found in forest borders a.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.17.6
- DOI:
- 10.4238/2012.September.17.6
Updates and perspectives on the utilization of molecular makers of complex traits in rice
Authors: G. Li S.W. Kwon Y.J. Park
After complete sequencing of its genome and annotation of the majority of its ~32,000 genes, rice genome has become the model genome among the cereal genomes, and the focus has shifted from structural to functional genomics and application of genomic-derived information in rice breeding. During the past 2 decades, intensive worldwide efforts have led to s.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.10.4
- DOI:
- 10.4238/2012.September.10.4
Isolation and characterization of 25 microsatellite DNA loci for Anopheles albitarsis sensu lato and inter-specific amplification in 5 congeneric species
Authors: G.M. GuimarĂ?£es-Marques J.S. Batista H.M. GuimarĂ?£es M.V. Naice-Daou M.P. Lima K.M. Formiga J.M.M. Santos C.A.P. Lima M.S. Rafael
The Anopheles albitasis complex includes 6 species, and 3 are considered as malaria vectors in Brazil. Twenty-five polymorphic microsatellite DNA loci were isolated and characterized in 24-36 individuals from the neighborhood of Puraquequara, Manaus, Amazonas State, Brazil. The number of estimated alleles ranged from 2 to 10, the observed heterozygosity rang.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.December.6.3
- DOI:
- 10.4238/2012.December.6.3