Cytogenomics
Association of bovine Toll-like receptor 4 with tick infestation rates and blood histamine concentration
Authors: G. Zhao1,2, M. Yu, Q.-W. Cui, X. Zhou, J.-C. Zhang, H.-X. Li, K.-X. Qu, G.-L. Wang and B.-Z. Huang
We investigated a possible association between bovine Toll-like receptor 4 (TLR4) and resistance to tick infestation in 103 cattle, including BMY cattle (1/2 Brahman, 1/4 Murray Grey, and 1/4 Yunnan Yellow cattle), Brahman, and Red Angus grazing on improved pasture. The tick infestation weight and number of Rhipicephalus microplus and the blood histamine .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.21
- DOI:
- 10.4238/2013.February.28.21
Gene expression in the lignin biosynthesis pathway during soybean seed development
Authors: A. Baldoni, E.V.R. Von Pinho, J.S. Fernandes, V.M. Abreu and M.L.M. Carvalho
The study of gene expression in plants is fundamental, and understanding the molecular mechanisms involved in important biological processes, such as biochemical pathways or signaling that are used or manipulated in improvement programs, are key for the production of high-quality soybean seeds. Reports related to gene expression of lignin in seeds are sca.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.2
- DOI:
- 10.4238/2013.February.28.2
Genetic variation in the parasympathetic signaling pathway in patients with reflex syncope
Authors: H.N. Holmegard, M. Benn, J. Mehlsen and S. Hauns�¸
Reflex syncope is defined by a self-terminating transient loss of consciousness associated with an exaggerated response of the vagal reflexes upon orthostatic challenges. A hereditary component has previously been suggested. We hypothesized that variations in genes encoding proteins mediating the vagal signaling in the heart may be involved in reflex sync.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.30.6
- DOI:
- 10.4238/2013.January.30.6
Multiplex ligation-dependent probe amplification detection of an unknown large deletion of the CREB-binding protein gene in a patient with Rubinstein-Taybi syndrome
Authors: F. Cal�¬, P. Failla, V. Chiavetta, A. Ragalmuto, G. Ruggeri, P. Schinocca, C. Schepis, V. Romano and C. Romano
Rubinstein-Taybi syndrome is a rare autosomal dominant congenital disorder characterized by postnatal growth retardation, psychomotor developmental delay, skeletal anomalies, peculiar facial morphology, and tumorigenesis. Mutations in the gene encoding the cAMP response element-binding protein (CREB, also known as CREBBP or CBP) on chromosome 16p13.3 have.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.7.2
- DOI:
- 10.4238/2013.January.7.2
Effects of polymorphisms in the bovine growth differentiation factor 9 gene on sperm quality in Holstein bulls
Authors: K.Q. Tang, W.C. Yang, X.X. Zhang and L.G. Yang
Members of the transforming growth factor-β (TGFβ) superfamily are critical regulators of germ cell development that act as extracellular ligands of the signal transduction pathways regulating proliferation, differentiation, apoptosis, and other aspects of cell behavior. Growth differentiation factor 9 (GDF9) is a member of the TGFβ superfa.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.4.1
- DOI:
- 10.4238/2013.July.4.1
Genetic diversity of stem cells and their functional impact on the development of neural tube defects in Eastern population of India
Authors: A.K. Saxena, S. Pandey and L.K. Pandey
Anencephaly and myelomeningocele are the 2 most common forms of neural tube defects (NTDs). During embryogenesis large numbers of extrinsic and intrinsic factors are responsible for the closing of the neural tube. “Stem cells” maintain the pluripotency during differentiation of 3 germ layers, including the neural ectoderm. We examined the role.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.15.1
- DOI:
- 10.4238/2013.July.15.1
Isolation and characterization of new polymorphic microsatellite markers from the cuttlefish Sepiella maindroni (Cephalopoda; Sepiidae)
Authors: B.-Y. Guo, P.Z. Qi, A.Y. Zhu, Z.M. Lv, W.C. Wang and C.W. Wu
Fifteen new polymorphic microsatellite loci were developed for the cuttlefish Sepiella maindroni. In 32 individuals from a wild population of coastal Ningde, Fujian Province, China, the number of alleles at these loci varied between 2 and 12, with an average of 5.86. The mean observed and expected heterozygosities were 0.6917 and 0.5993, respectively. Amo.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.11.1
- DOI:
- 10.4238/2013.July.11.1
Mapping codon usage in sequence regions flanking cleavage positions in the hepatitis A virus polyprotein
Authors: X.-X. Ma, Y.-P. Feng, L. Chen, Y.-Q. Zhao, J.-L. Liu, J.-Z. Guo, P.-H. Guo, J.-T. Yang, J.-X. Lu, S.-E. Chen and Z.-R. Ma
To analyze the synonymous codon usage patterns of sequence regions flanking cleavage sites in the hepatitis A virus (HAV) polyprotein, the codon usage bias at codon positions and the synonymous codon usage in the target contexts of 30 virus strains were estimated by two simple methods that were based on the values for relative synonymous codon usage. In a.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.8.11
- DOI:
- 10.4238/2013.July.8.11
Recycling of superfine resolution agarose gel
Authors: T.-Y. Seng, R. Singh, Q.Z. Faridah, S.-G. Tan and S.S.R.S. Alwee
Genetic markers are now routinely used in a wide range of applications, from forensic DNA analysis to marker-assisted plant and animal breeding. The usual practice in such work is to extract the DNA, prime the markers of interest, and sift them out by electrically driving them through an appropriate matrix, usually a gel. The gels, made from polyacrylamid.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.11.1
- DOI:
- 10.4238/2013.March.11.1
Genetic diversity and selection gain in the physic nut (Jatropha curcas)
Authors: B.P. Brasileiro, S.A. Silva, D.R. Souza, P.A. Santos, R.S. Oliveira and D.H. Lyra
The use of efficient breeding methods depends on knowledge of genetic control of traits to be improved. We estimated genetic parameters, selection gain, and genetic diversity in physic nut half-sib families, in order to provide information for breeding programs of this important biofuel species. The progeny test included 20 half-sib families in 4 blocks a.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.12
- DOI:
- 10.4238/2013.January.4.12