Cytogenomics
Cytogenetic and random amplified polymorphic DNA analysis of Leptodactylus species from rural and urban environments (Anura, Amphibia)
Authors: M.P. Arruda and E. Morielle-Versute
Cytogenetic and random amplified polymorphic DNA analyses carried out in the species Leptodactylus podicipinus, L. ocellatus, L. labyrinthicus, and L. fuscus from rural and urban habitats of the northwest region of São Paulo State, Brazil, showed that the karyotypes (2n = 22), constitutive heterochromatin distribution and nucleolus organizer region.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr402
- DOI:
- 10.4238/vol7-1gmr402
Structural evaluation of type 3 dopaminergic receptor gene (DRD3) in chronic anovulatory women
Authors: A.D.S. Santos, R.A.A. Prado, M.B. Melo, M.R. Melo and C.A. Longui
Dopamine receptor type 3 (DRD3) expressed in the limbic system sites involved in the regulation of GnRH seems to play a role in neuroendocrine control. We hypothesized that women with chronic anovulation should show exacerbated secretion of prolactin (PRL) after thyrotropin-releasing hormone (TRH) stimulation test, having more chances for dopamine inhibit.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr397
- DOI:
- 10.4238/vol7-1gmr397
genetic evaluation of the HSP70 protein in the japanese quail (Coturnix japonica)
Authors: H.C.T. Gaviol, E. Gasparino, A.J. Prioli and M.A.M. Soares
Heat stress is one of the main problems in modern aviculture, since it affects birds especially in the final phase of rearing, causing bird mortality and economic losses to the aviculturist. The quail, as most birds, has difficulties in dissipating heat. However, little is known about the mechanism that controls the responses of the organism to stressor a.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr354
- DOI:
- 10.4238/vol7-1gmr354
Production of the refolded oligopeptide-binding protein (OppA) encoded by the citrus pathogen Xanthomonas axonopodis pv. citri
Authors: A. Balan, C.S. Souza, R.C.C. Ferreira, L.C.S. Ferreira
The oligopeptide-binding protein, OppA, binds and ushers oligopeptide substrates to the membrane-associated oligopeptide permease (Opp), a multi-component ABC-type transporter involved in the uptake of oligopeptides expressed by several bacterial species. In the present study, we report the cloning, purification, refolding and conformational analysis of a.. Read More»
- Genet. Mol. Res. 7(1):
- vol7-1gmr392
- DOI:
- 10.4238/vol7-1gmr392
A multi-neighbor-joining approach for phylogenetic tree reconstruction and visualization
Authors: Ana Estela A. da Silva, Wilfredo J.P. Villanueva, Helder Knidel, VinÃ?Âcius Bonato, SÃ?©rgio F. dos Reis and Fernando J. Von Zuben
The computationally challenging problem of reconstructing the phylogeny of a set of contemporary data, such as DNA sequences or morphological attributes, was treated by an extended version of the neighbor-joining (NJ) algorithm. The original NJ algorithm provides a single-tree topology, after a cascade of greedy pairing decisi.. Read More»
- Genet. Mol. Res. 4(3):
Uses and limitations of two molecular cytogenetic techniques for the study of arrested embryos obtained through assisted reproduction technology
Authors: Maria C. Muhlmann, Alejandro O. Laudicina, Claudia Perandones, Maria V. Bertolino, Andrea Marazzi, Carlos J. Quintans, Monica Donaldson, Walter Bozzo and Sergio Pasqualini
We studied chromosomal abnormalities in arrested embryos produced by assisted reproductive technology with fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH) in order to determine the best technique for evaluating chromosomal aneusomies to be implemented in different situations. We examined i.. Read More»
- Genet. Mol. Res. 4(2):
Osteosarcoma arising from osteochondroma of the tibia: case report and cytogenetic findings
Authors: E.E. Engel, M.H. Nogueira-Barbosa, M.S. Brassesco, G.E.B. Silva, E.T. Valera, F.M. Peria, T.C. Motta and L.G. Tone
Osteochondroma is a cartilage capped benign tumor developing mainly at the juxta-epiphyseal region of long bones. The rate of malignant transformation, mainly into chondrosarcoma, is estimated to be less than 1-3%. Transformation into osteosarcoma is very rare and has been reported only thirteen times. There is little informat.. Read More»
- Genet. Mol. Res. 11(1):
- 2012.March.1.1
- DOI:
- 10.4238/2012.March.1.1
Novel SNPs in the growth arrest and DNA damage-inducible protein 45 alpha gene (GADD45A) associated with meat quality traits in Berkshire pigs
Authors: E.S. Cho, K.T. Lee, J.W. Choi, H.J. Jeon, S.W. Lee, Y.M. Cho and T.H. Kim
This study was conducted to evaluate the porcine gene GADD45A (growth arrest and DNA-damage-inducible protein 45 alpha) as a positional candidate controlling quantitative trait loci (QTL) for meat quality traits on chromosome 6 (SSC6). Four exons of the porcine GADD45A gene were defined from cDNA and BAC clone sequences. A total of 4 single nucleotide pol.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.6
- DOI:
- 10.4238/2015.July.31.6
Genomic selection of seed weight based on low-density SCAR markers in soybean
Authors: Y.J. Shu, D.S. Yu, D. Wang, X. Bai, Y.M. Zhu and C.H. Guo
With the development of molecular marker technology, crop breeding has been accelerated by marker-assisted selection for the improvement of quantitative traits. However, due to the traits’ polygenic nature, traditional marker-assisted selection methods are ill-suited for identification of quantitative trait loci. Genomic selection (GS) was introduce.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.3.2
- DOI:
- 10.4238/2013.July.3.2
Assessment of genotoxic, cytotoxic, and protective effects of Salacia crassifolia (Mart. Ex. Schult.) G. Don. stem bark fractions in mice
Authors: C.C. Carneiro, C.R. Silva, A.C.S. Menezes, C.N. P�©rez and L. Chen-Chen
Salacia crassifolia (Mart. Ex. Schult.) G. Don., popularly known in Brazil as “bacupari”, “cascudo”, and “saputá”, is a shrub of the Celastraceae family that is unique to the Brazilian Cerrado region. In folk medicine, this plant has been mainly used to treat skin cancer and gastric ulcers. In the present study, .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.3.1
- DOI:
- 10.4238/2013.July.3.1