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Heterotic groups in tropical maize germplasm by test crosses and simple sequence repeat markers
Authors: C.G. Aguiar, I. Schuster, A.T. Amaral J�ºnior, C.A. Scapim and E.S.N. Vieira
The objectives of the present study were to determine heterotic groups of germplasm lines of tropical maize by test crosses and by simple sequence repeat (SSR) markers and to compare five grouping methods of heterogeneous maize. Sixteen lines of nine populations in the S5 generation were evaluated in test crosses with three testers. The results of four ex.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr495
- DOI:
- 10.4238/vol7-4gmr495
Relationship between multiple paternity and reproductive parameters for Podocnemis sextuberculata (Testudines Podocnemididae) in the Trombetas River, Brazil
Authors: F.P. Freda1, V.C.D. Bernardes1, C.C. Eisemberg3, C. Fantin2 and R.C. Vogt1
Genetic studies of multiple paternity are a valuable tool to gain information on the reproductive biology of turtles. We analyzed paternity type in Podocnemis sextuberculata and related number of fathers per nest to nesting period (beginning, middle, or end of nesting season); clutch size (number of eggs); female size; and hatchling success. Females were .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017335
- DOI:
- 10.4238/gmr.15017335
Comprehensive gene expression analysis of the DNA (cytosine-5) methyltransferase family in rice (Oryza sativa L.)
Authors: F. Ahmad, X. Huang, H.X. Lan, T. Huma, Y.M. Bao, J. Huang and H.S. Zhang
Cytosine DNA methylation is a conserved epigenetic regulatory mechanism in both plants and animals. DNA methyltransferases (DNA MTases) not only initiate (de novo) but also maintain the process of DNA methylation. Here, we characterized the genome-wide expression profiles of 10 cytosine DNA MTase genes belonging to 4 .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.7.9
- DOI:
- 10.4238/2014.July.7.9
Mutations in WT1 in boys with sporadic isolated steroid-resistant nephrotic syndrome
Authors: Y. Yang1,2,3*, F. Zhao1,2,3*, X. Tu4 and Z. Yu1,2,3
Mutations in the Wilms’ tumor gene, WT1, can lead to syndromic steroid-resistant nephrotic syndrome and isolated steroid-resistant nephrotic syndrome. WT1 mutations have been identified in the majority of children with Denys-Drash or Frasier syndrome. WT1 mutations have not previously been identified in boys with sporadic isolated steroid-resistant .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017559
- DOI:
- 10.4238/gmr.15017559
E2F, HSF2, and miR-26 in thyroid carcinoma: bioinformatic analysis of RNA-sequencing data
Authors: J.C. Lu and Y.P. Zhang
In this study, we examined the molecular mechanism of thyroid carcinoma (THCA) using bioinformatics. RNA-sequencing data of THCA (N = 498) and normal thyroid tissue (N = 59) were downloaded from The Cancer Genome Atlas. Next, gene expression levels were calculated using the TCC package and differentially expressed genes (DEGs) were identified using the ed.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017576
- DOI:
- 10.4238/gmr.15017576
Effects of hydroxycamptothecin on the expression of matrix metalloproteinase-1 (MMP-1), tissue inhibitor of MMP-1, and type I collagen in rats with pulmonary fibrosis
Authors: G.-X. Hu, S.-T. Yao, L.-H. Zeng, Y.-Z. Peng and J. Zheng
The aim of this study was to investigate the effects of hydroxycamptothecin (HCPT) on the expression of matrix metalloproteinase-1 (MMP-1), tissue inhibitor of MMP-1 (TIMP-1), and type I collagen in the lung tissue of rats with pulmonary fibrosis induced by bleomycin A5. We used hematoxylin eosin staining to observe the degree of pulmonary fibrosis in rat.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.21
- DOI:
- 10.4238/2015.May.4.21
Whole-exome sequencing reveals a novel COL2A1 mutation in a patient with spondyloÃ?Âepiphyseal dysplasia congenita
Authors: Sangsin1,2,3,4, C. Srichomthong3,4, M. Pongpanich5,6, K. Suphapeetiporn3,4 and V. Shotelersuk3,4
Skeletal dysplasia is a group of disorders with more than 450 entities, many of which cannot be differentiated, especially during infancy, but could lead to different clinical courses and prognoses. In this study, we have described a case of a Thai infant with short stature, flat face, pectus carinatum, indirect inguinal hernia, platyspondyly, and general.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017624
- DOI:
- 10.4238/gmr.15017624
Regulation of cotton fiber elongation by xyloglucan endotransglycosylase/hydrolase genes
Authors: M.Y. Shao, X.D. Wang, M. Ni, N. Bibi, S.N. Yuan, W. Malik, H.P. Zhang, Y.X. Liu and S.J. Hua
Ligon lintless mutant (li1li1) with super-short fibers (5-8 mm in length) and its wild type (Li1Li1) with normal fibers (30 mm in length) were used to study the function of xyloglucan endotransglycosylase/hydrolase (XTH) genes during fiber elongation in cotton. Wild-type cotton attained the fiber elongation stage earlier (5 da.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.27.1
- DOI:
- 10.4238/2011.October.27.1
Expression profiles of phosphatidylinositol phosphate kinase genes during normal human in vitro erythropoiesis
Authors: T.R. Zaccariotto C. Lanaro D.M. Albuquerque M.N.N. Santos M.A.C. Bezerra F.G.P. Cunha I. Lorand-Metze A.S. Araujo F.F. Costa M.F. Sonati
Phosphatidylinositol phosphate kinases (PIPKs) are enzymes that participate in diverse intracellular signaling pathways. They are classified into 3 functionally distinct subfamilies - PIPKI (a, b, g), PIPKII (a, b, g), and PIPKIII - located in various subcellular compartments. Recently, the PIPKIIa and b-globin genes were found to be overexpressed in reticul.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.3
- DOI:
- 10.4238/2012.November.12.3
Comparative genomics of grasses tolerant to aluminum
Authors: Jardim SN
The family Poaceae includes over 10,000 species, among which are the most economically important cereals: maize, sorghum, rice, wheat, rye, barley, and oat. These cereals are very important components of human and animal food. Although divergence of the members of this family occurred about 40 million years ago, comparative ge.. Read More»
- Genet. Mol. Res. 6(4):