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Exhaustive search for conservation networks of populations representing genetic diversity
Authors: J.A.F. Diniz-Filho1, J.V.B.P.L. Diniz2 and M.P.C. Telles3
Conservation strategies routinely use optimization methods to identify the smallest number of units required to represent a set of features that need to be conserved, including biomes, species, and populations. In this study, we provide R scripts to facilitate exhaustive search for solutions that represent all of the alleles in networks with the smallest .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017525
- DOI:
- 10.4238/gmr.15017525
Phylogenetic relationships of the Hucul horse from Romania inferred from mitochondrial D-loop variation
Authors: S.E. Georgescu, M.A. Manea, A. Dudu and M. Costache
The existence of the Hucul horse on Romanian territory has been documented from the very distant past; today Hucul is a unique breed that is part of the FAO Program for the Preservation of Animal Genetic Resources. We compared Hucul with several primitive European and Asiatic breeds in order to elucidate the origin of these ho.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.7
- DOI:
- 10.4238/2011.October.31.7
Obese gene polymorphism in Pietrain and large white pigs after a divergent selection
Authors: A.C.P. Silveira, R.C. Antunes, J.F. Almeida, T.F. Braga, P.F.A. Freitas, A.S.M. C�©sar and E.C. Guimar�£es
The aim of the present study was to identify polymorphisms in the leptin gene of 112 pigs and compare the maternal and paternal lineage of Pietrain and Large White breeds that underwent a divergent selection for over 30 years. DNA samples extracted from the blood of these animals were amplified by polymerase chain reaction and genotyped by restriction fra.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr511
- DOI:
- 10.4238/vol7-4gmr511
Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population
Authors: H. Bulut, M. Pehlivan, S. Alper, A.G. Tomatir, H. Onay, S.E. Y�¼ksel, F. ��zkinay and S. Pehlivan
Accumulation of hydrogen peroxide (H2O2) and low catalase (CAT) activity have been demonstrated in the epidermis of vitiligo patients. We investigated a possible association between the CAT exon 9 (Asp-389) gene and vitiligo susceptibility in the Turkish population. Thirty-four patients with vitiligo and 49 gender, age and eth.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.13
- DOI:
- 10.4238/2011.October.31.13
Screening of key genes of unruptured intracranial aneurysms by using DNA microarray data analysis techniques
Authors: L. Chen, Y. Fan and J. Wan
This study aimed to identify differentially expressed genes (DEGs) of unruptured intracranial aneurysms (IAs) and provide beneficial information for early diagnosis and treatment of IAs. The gene expression profile GSE26969 from the Gene Expression Omnibus database was downloaded, which included six human IA samples: three int.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.31.2
- DOI:
- 10.4238/2014.January.31.2
Molecular characterization of an expressed sequence tag representing the cuticle-degrading serine protease gene (PII) from the nematophagous fungus Arthrobotrys oviformis by differential display technology
Authors: A. Nagee, A. Acharya, A. Shete, P.N. Mukhopadhyaya and B.A. Aich
The technology of mRNA-based differential display reverse transcriptase-polymerase chain reaction (DDRT-PCR) was used to detect a 246-bp differentially expressed fragment from the nematophagous fungus Arthrobotrys oviformis when young mycelia were induced with the round worm Haemonchus contortus. The fragment was converted into an expressed sequence tag (.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr487
- DOI:
- 10.4238/vol7-4gmr487
De novo assembly and characterization of Gleditsia sinensis transcriptome and subsequent gene identification and SSR mining
Authors: S. Han, Z. Wu, X. Wang, K. Huang, Y. Jin, W. Yang and H. Shi
Gleditsia sinensis is a Chinese native deciduous tree with a high economic and medicinal value. However, there is limited knowledge on the molecular processes responsible for the medical properties of this species owing to lack of bioinformatic resources such as available whole-genome sequences. In the present study, RNA sequencing data were used to analy.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017740
- DOI:
- 10.4238/gmr.15017740
Genetic variation and balancing selection at MHC class II exon 2 in cultured stocks and wild populations of orange-spotted grouper (Epinephelus coioides)
Authors: Z.N. Meng S. Yang B. Fan L. Wang H.R. Lin
Major histocompatibility complex (MHC) molecules play vital roles in triggering adaptive immune responses and are considered the most variable molecules in vertebrates. Recently, many studies have focused on the polymorphism and evolution mode of MHC in both model and non-model organisms. Here, we analyzed the MHC class II exon 2-encoding Ã?² chain in compa.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.4
- DOI:
- 10.4238/2012.November.12.4
Selection of putative Terra Maranh�£o plantain cultivar mutants obtained by gamma radiation
Authors: R.V. Reis, E.P. Amorim, C.A.S. Ledo, R.K.N. Pestana, Z.S. Gon�§alvesand A. Bor�©m
The aim of this study was to select putative Terra Maranhão plantain cultivar mutants obtained by gamma radiation, with good agronomic traits and short height. A total of 315 buds were irradiated in vitro with gamma rays in doses of 20 Gy and were subcultivated and evaluated in the field over 2 production cycles. The clones were evaluated to select.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.1
- DOI:
- 10.4238/2015.May.11.1
Developmental methylation pattern regulates porcine GPR120 expression
Authors: H.M. Wang*, J.D. Ma*, L. Jin, Y.H. Liu, T.D. Che, M.Z. Li and X.W. Li
DNA methylation is an important component of the epigenetic machinery and plays a critical role in transcriptional regulation. It mostly occurs in CpG abundant regions, known as CpG islands (CGIs). G protein-coupled receptor 120 (GPR120) functions as an omega-3 fatty acid receptor and is involved in multiple-biological processes, including lipogenesis. He.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15014240
- DOI:
- 10.4238/gmr.15014240